아멘토플라본

아멘토플라본
아멘토플라본 구조식 이미지
카스 번호:
1617-53-4
한글명:
아멘토플라본
동의어(한글):
아멘토플라본
상품명:
Amentoflavone
동의어(영문):
AMENTOFLAVONE;AMENTOFLACONE;amenthoflavone;I3,II8 BIAPIGENIN;3',8''-BIAPIGENIN;AMENTOFLAVONE(SH);Amentoflavone >AMENTOFLAVONE hplc;DIDEMETHYL-GINKGETIN;AMentotaxus biflavone
CBNumber:
CB3744024
분자식:
C30H18O10
포뮬러 무게:
538.46
MOL 파일:
1617-53-4.mol
MSDS 파일:
SDS

아멘토플라본 속성

녹는점
>300°C (dec.)
끓는 점
910.5±65.0 °C(Predicted)
밀도
1.656±0.06 g/cm3(Predicted)
저장 조건
Inert atmosphere,2-8°C
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨, 가열), 피리딘(약간 용해됨)
산도 계수 (pKa)
6.01±0.40(Predicted)
색상
노란색
BRN
380244
InChIKey
YUSWMAULDXZHPY-UHFFFAOYSA-N
LogP
3.492 (est)
CAS 데이터베이스
1617-53-4(CAS DataBase Reference)

안전

안전지침서 22-24/25
WGK 독일 3
F 고인화성물질 10
HS 번호 29329990

아멘토플라본 C화학적 특성, 용도, 생산

개요

Amentoflavone is a biflavonoid originally isolated from Selaginella. It has a wide variety of biological effects including antibacterial, antioxidant, antiviral, antidiabetic, and neuroprotective activities. Amentoflavone has antiviral activity against the influenza A subtypes H1N1 and H3N2, influenza B, and herpes simplex virus 1 (EC50s = 3.1 and 4.3, 0.56, and 17.9 μg/ml, respectively). It has antidiabetic effects such that it dose-dependently increases insulin receptor phosphorylation and activation and inhibits hydrolysis of p-nitrophenyl phosphate (p-NPP) catalyzed by protein tyrosine phosphatase 1B (PTP1B; IC50 = 7.3 μM). Amentoflavone reduces the time mice spend immobile in the forced swim test, a measure of antidepressant efficacy, in a dose-dependent manner.

Biochem/physiol Actions

Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs. Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site.

아멘토플라본 준비 용품 및 원자재

원자재

준비 용품


아멘토플라본 공급 업체

글로벌( 267)공급 업체
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Hangzhou ICH Biofarm Co., Ltd
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BINBO BIOLOGICAL CO.,LTD
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Henan Tianfu Chemical Co.,Ltd.
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Nanjing ChemLin Chemical Industry Co., Ltd.
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Shanghai Zheyan Biotech Co., Ltd.
18017610038
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Chengdu Greenpure Biopharma CO.,Ltd
18283602253
jancyzheng@gcgreenpure.com China 952 58
career henan chemical co
+86-0371-86658258
sales@coreychem.com China 29914 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897
sales@biopurify.com China 3424 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58

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