이소프로필아민
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이소프로필아민 속성
- 녹는점
- -101 °C
- 끓는 점
- 32-35 °C 33-34 °C (lit.)
- 밀도
- 0.688 g/mL at 20 °C (lit.)
- 증기 밀도
- 2.04 (vs air)
- 증기압
- 9.2 psi ( 20 °C)
- 굴절률
- n
20/D 1.374(lit.)
- 인화점
- −26 °F
- 저장 조건
- 2-8°C
- 용해도
- 1000g/L
- 물리적 상태
- 결정성 분말, 바늘 또는 결정체
- 산도 계수 (pKa)
- 10.63(at 25℃)
- 색상
- APHA: ≤50
- 냄새
- 강한 암모니아성; 자극적이고 자극적이며 전형적인 아민.
- 수소이온지수(pH)
- 13 (700g/l, H2O, 20℃)
- 폭발한계
- 2-10.4%(V)
- Odor Threshold
- 0.025ppm
- ?? ??
- 비린내
- 수용성
- 녹는
- 감도
- Air Sensitive
- JECFA Number
- 1581
- Merck
- 14,5209
- BRN
- 605259
- 노출 한도
- TLV-TWA 5 ppm (~12 mg/m3) (ACGIH, MSHA, and OSHA); TLV-STEL 10 ppm(~24 mg/m3) (ACGIH); IDLH 4000 ppm (NIOSH).
- Dielectric constant
- 5.5(20℃)
- 안정성
- 안정적인. 가연성이 매우 높음 - 끓는점이 낮고 인화점이 낮습니다. 공기와 쉽게 폭발성 혼합물을 형성합니다. 강산화제, 산, 산 염화물, 산 무수물, 퍼클로릴 플루오라이드와 호환되지 않습니다.
- LogP
- 0.21
- CAS 데이터베이스
- 75-31-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F+,Xi,T | ||
---|---|---|---|
위험 카페고리 넘버 | 12-36/37/38-37-35-25-20/21 | ||
안전지침서 | 16-26-29-45-36/37/39 | ||
유엔번호(UN No.) | UN 1221 3/PG 1 | ||
WGK 독일 | 1 | ||
RTECS 번호 | NT8400000 | ||
F 고인화성물질 | 34 | ||
자연 발화 온도 | 755 °F | ||
TSCA | Yes | ||
HS 번호 | 2921 19 99 | ||
위험 등급 | 3 | ||
포장분류 | I | ||
유해 물질 데이터 | 75-31-0(Hazardous Substances Data) | ||
독성 | LD50 orally in rats: 820 mg/kg (Smyth) | ||
IDLA | 750 ppm | ||
기존화학 물질 | KE-29257 |
이소프로필아민 C화학적 특성, 용도, 생산
개요
Isopropylamine (propan-2-amine, IUPAC) is a colorless, volatile liquid. It is highly flammable, with a flammable range of 2%–10.4% in air. Boiling point is 93°F (33°C), flash point is ?15°F (?26°C), and ignition temperature is 756°F (402°C).It is miscible with water, with a specific gravity of 0.69, which is lighter than water. Vapor density is 2.04, which is heavier than air. In addition to flammability, isopropylamine is a strong irritant to tissue and has a TLV of 5 ppm in air. The four-digit UN identification number is 1221. The NFPA 704 designation for isopropylamine is health 3, flammability 4, and reactivity 0. Primary uses for isopropylamine are pharmaceuticals, dyes, insecticides, and as a dehairing agent.
화학적 성질
Isopropylamine is a colorless, flammable liquid. Isopropylamine is miscible with water, alcohol, and ether.The odor threshold reportedly ranges from 0.21 to 0.70 ppm; the pungent, ammoniacal odor becomes irritating at 24mg/m3 (110).물리적 성질
Colorless liquid with a penetrating, ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 500 μg/m3 (210 ppbv) and 1.7 mg/m3 (700 ppbv), respectively (Hellman and Small, 1974). An odor threshold concentration of 25 ppbv was reported by Nagata and Takeuchi (1990).출처
Not reported found in natu용도
Isopropylamine is used as a dehairing agentand as an intermediate in the preparation ofmany organics.생산 방법
Isopropylamine can be produced from the corresponding alcohol by reacting with ammonia in the presence of a dehydrating catalyst, or from the chloride by reacting with ammonia under pressure. It is also reported that this amine can be produced from acetone and ammonia or from the acetone oxime (HSDB 1989).정의
ChEBI: A member of the class of alkylamines that is propane carrying an amino group at position 2.일반 설명
A clear colorless liquid with an ammonia-like odor. Flash point -35°F. Boiling point 90°F. Less dense than water Vapors heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a solvent and to make other chemicals.공기와 물의 반응
Highly flammable. Water soluble.반응 프로필
Isopropylamine is a colorless, alkaline liquid, very volatile, moderately toxic, highly flammable. Dangerous fire hazard when exposed to heat, flame, sparks, or strong oxidizers. When heated to decomposition Isopropylamine emits toxic fumes of oxides of nitrogen [M. K.]. A mixture of Isopropylamine and perchloryl fluoride resulted in an uncontrolled oxidation and/or explosion, [J. Org. Chem., 1980, 45, 4036]. The reaction of 1-chloro-2,3-epoxypropane and the amine and most probably other nitrogen bases, yields a violent exotherm, [Chem. & Ind., 1971, 994].위험도
Highly flammable, dangerous fire risk. Strong irritant to tissue.건강위험
Isopropylamine is a strong irritant to theeyes, skin, and respiratory system. A shortexposure to 10–20 ppm can cause irritationof the nose and throat in humans (Procturand Hughes 1978). Prolonged exposure tohigh concentrations may lead to pulmonaryedema. Skin contact can cause dermatitisand skin burns. Exposure to 8000 ppm for4 hours was lethal to rats.LD50 value, oral (mice): 2200 mg/kg.
화학 반응
Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.공업 용도
Isopropylamine can be used as a dehairing agent and as a solvent. It also finds use as an intermediate in the production of insecticides, herbicides and bactericides and in the production of pharmaceuticals, dyes and rubber accelerators (HSDB 1989).환경귀착
Photolytic. Low et al. (1991) reported that the photooxidation of aqueous primary amine solutions by UV light in the presence of titanium dioxide resulted in the formation of ammonium and nitrate ions.Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987). Forms water-soluble salts with acids.
신진 대사
One would expect isopropylamine to be readily absorbed from the gut and respiratory tract. Shorter chain aliphatic amines such as isopropylamine also are efficiently absorbed through the skin (Beard and Noe 1981). When administered intravenously, isopropylamine distributed rapidly into tissue compartments with tissue/plasma ratios ranging from 1.8 in the atrium to 16.7 in the renal medulla (Privitera et al 1982). During the elimination phase, a half-life of 146 min was observed in plasma. There do not appear to be any definitive metabolic studies with this compound, however through a comparison with other substrates, one might expect oxidation to acetone and ammonia through the action of monoamine oxidase (Tipton 1980).이소프로필아민 준비 용품 및 원자재
원자재
준비 용품
Befunolol
N-터트-부틸-N-이소프로필티오요소
1,4-비스((1-메틸에틸)아미노)-9,10-안트라센디온
DIPROPETRYN
CARAZOLOL HCL
프로메트린
1-이소프로필-4-피페리돈
(-)-2-베타-탄소메톡시-3-베타-(4-플루오로페닐)트로판
N-이소프로필아크릴아마이드
올시프레나린
N-이소프로필노르트로피닐A하이드록시메틸)페닐아세테이트
3-ISOPROPYLAMINO-PROPIONIC ACID ETHYL ESTER X HCL >98%
N-(2-METHOXYETHYL)METHYLAMINE
브로목시닐
핀도롤
Propyl isocyanate
Nilutamide
1-ISOPROPYL-5-HYDROXYPYRAZOL
2-BROMO-3-FORMYLPYRIDINE
ISOFENPHOS-METHYL
U-47319
브푸로페진
3-MORPHOLIN-4-YL-PROPIONIC ACID
8-이소프로필-8-아자비시클로[3.2.1]옥트-3-일엔도-(±)-포르밀페닐아세테이트
다이아이소프로필아민
4-(브로모메틸)-N-(L-메틸레틸)벤즈아미드
AMIPROFOS METHYL
아트라진
이소펜포스
이프로다이온
페나미포스
벤타존
4-(4-(클로로페닐)이미노)-1-이소프로필피페리딘
Lorcainide
클로르프레날린
N-(4-클로로페닐)-1-이소프로필피페리딘-4-아민
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]ethan-1-one
이소프로필아민 공급 업체
글로벌( 445)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co.,Ltd | +86-15028179902 |
angelia@hbmojin.com | China | 1069 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12446 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8820 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 |
info@longyupharma.com | China | 2534 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |