Nafarelin Acetate
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Nafarelin Acetate 속성
- 녹는점
- >181oC (dec.)
- 저장 조건
- 2-8°C
- 용해도
- H2O: >5mg/mL
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 하얀색
안전
| WGK 독일 | 3 |
|---|
Nafarelin Acetate C화학적 특성, 용도, 생산
개요
Nafarelin acetate is a synthetic decapeptide agonist analog of the natural gonadotropin-releasing hormone, differing in the amino acid at position 6 where D-naphthylalanine has been substituted for glycine. This substitution gives nafarelin greater potency and a substantially longer half-life than the endogenous hormone. Nafarelin acetate administered as a nasal spray, suppresses estrogen levels on repeated dosing and is indicated for the management of endometriosis. It also has orphan drug status for use in precocious puberty.용도
Nafarelin Acetate is a gonadotropin-releasing hormone agonist. Treatment with Nafarelin improves sleep disturbances and anxiety-depression. Nafarelin is also used in the treatment of estrogen-dependent gynecologic disorders such as endometriosis and uterine leiomyomas.Clinical Use
Nafarelin acetate, contains D Nal(2)6 [Nal = 3-(2-naphthyl)-Ala] in place of Gly6, but the C-terminus, Gly10-NH2, is identical with natural GnRH. Nafarelin acetate is available as a 0.2% nasal spray for the relief of endometriosis. Estrogen, of course, is needed for the growth of endometrial tissue; thus, decreased estrogen leads to shrinkage of errant endometrial tissue. The observed side effects of nafarelin acetate are related to falling estrogen levels and include decreased libido, amenorrhea, hot flashes, and vaginal dryness. When used consistently, nafarelin acetate will inhibit ovulation and stop menstruation.Nafarelin acetate also is used in children, male and female, for the treatment of central precocious puberty. By suppressing the release of LH, the estradiol or testosterone levels fall to prepubertal levels; early secondary sexual development is arrested, linear growth and skeletal maturation are slowed, and in girls, menstruation stops.
Nafarelin Acetate 준비 용품 및 원자재
원자재
불산
BOC-Glycine
1-Boc-Pyrrolidine
BOC-L-Leucine
Boc-3-(2-Naphthyl)-D-alanine
BOC-L-Proline
COBALT(III) FLUORIDE
1-하이드록시벤조트리아졸 일수화물
N-알파-T-BOC-L-트립토판
준비 용품
Nafarelin Acetate 공급 업체
글로벌( 61)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 |
info@cellmano.com | China | 999 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| Wuhan Cell Pharmaceutical Co., Ltd | +86-13129979210 +86-13129979210 |
sales@cellwh.com | China | 376 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Shijiazhuang Jianxin Biotechnology Co., LTD | +undefined+86-17692708569 |
liyingjian1997@gmail.com | China | 787 | 58 |
| DONBOO AMINO ACID COMPANY | +8613063595538 |
donboo@donboo.com | China | 9365 | 58 |
Nafarelin Acetate 관련 검색:
Leuprorelin acetate
Goserelin acetate
Ornipressin
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DESMOPRESSIN
Argipressine acetate
Abarelix
Pralmorelin
Cetrorelix acetate
Gonadorelin acetate
Alarelin Acetate
Pramlintide
Sermorelin acetate
Vapreotide Acetate
tetracosactrin acetate
Desmopressin Acetate impurity
Teriparatideacetate
Triptorelin acetate