트라폭신A
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트라폭신A 속성
- 저장 조건
- -20°C
- 용해도
- DMSO: 용해성 0.9-1.10 mg/ml, 투명, 무색 ~ 희미한 노란색(H2O에 20배 더 희석할 수 있음)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
트라폭신A C화학적 특성, 용도, 생산
개요
Trapoxin A is a cyclotetrapeptide histone deacetylase (HDAC) inhibitor. It inhibits HDAC activity in a concentration-dependent and irreversible manner. Trapoxin A inhibits proliferation of NIH3T3 cells transformed by the oncogene v-sis (sis/NIH3T3; IC50 = ~200 ng/ml) and has detransformation activity, flattening sis/NIH3T3 cells when used at a concentration of 1 ng/ml. It also halts the cell cycle at the G2 phase in 3Y1 fibroblasts when used at a concentration of 10 nM and inhibits growth of TR303 cells resistant to trichostatin A at a concentration of 50 ng/ml.용도
Trapoxin A has been used:- to study its effects on the inhibition of histone deacetylase 11 (HDAC11)
- to study its effects on the inhibition of HDAC3 in human cell lines
- to study its effects on the inhibition of HDAC6 in rat pyramidal neurons
정의
ChEBI: A homodetic cyclic tetrapeptide constructed from L-phenylalanyl (x2), D-pipecolinyl and L-2-amino-8-oxo-9,10-epoxydecanoyl residues.트라폭신A 준비 용품 및 원자재
원자재
준비 용품
트라폭신A 공급 업체
글로벌( 8)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
BOC Sciences | 16314854226 |
info@bocsci.com | United States | 9926 | 65 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
InvivoChem | 13549236410 |
sales@invivochem.cn | China | 6755 | 58 |
트라폭신A 관련 검색:
사이클렌
Pipecolamide
ETHYL[(1-METHYLPIPERIDIN-2-YL)METHYL]AMINE
N-methylpiperidine-2-carboxamide
trapoxin A
N-(PIPERIDINOETHYL)ETHYLENEDIAMINE
2-(2-methylpiperidin-1-yl)ethanamine
1-ethylpiperidine-2-methylamine
CHEMBRDG-BB 4015189
(1-BUTYL-2-PIPERIDINYL)-N-METHYLMETHANAMINE
N-[(1-BUTYL-2-PIPERIDINYL)METHYL]ETHANAMINE
ETHYL[(1-PROPYLPIPERIDIN-2-YL)METHYL]AMINE
N-[(1-ETHYL-2-PIPERIDINYL)METHYL]-1-PROPANAMINE
ETHYL[(1-ETHYLPIPERIDIN-2-YL)METHYL]AMINE
N-[(1-PROPYL-2-PIPERIDINYL)METHYL]-1-PROPANAMINE
BUTYL[(1-PROPYLPIPERIDIN-2-YL)METHYL]AMINE
BUTYL[(1-ETHYLPIPERIDIN-2-YL)METHYL]AMINE
(1-ETHYL-2-PIPERIDINYL)-N-METHYLMETHANAMINE