ChemicalBook
Chinese English Japanese Germany Korea

포스파미돈

포스파미돈
포스파미돈 구조식 이미지
카스 번호:
13171-21-6
한글명:
포스파미돈
동의어(한글):
포스파미돈;포스파마이돈
상품명:
PHOSPHAMIDON
동의어(영문):
c570;ml97;nch];RILAN;C 570;ML 97;Dixon;RIMDON;Merkon;or1191
CBNumber:
CB7451007
분자식:
C10H19ClNO5P
포뮬러 무게:
299.69
MOL 파일:
13171-21-6.mol

포스파미돈 속성

녹는점
120-123℃
끓는 점
bp1.5 162°; bp0.001 120°
밀도
1.2132 g/cm3 (20 ºC)
증기압
2.2×10-3 Pa (25 °C)
굴절률
1.4718 (589.3 nm 25℃)
저장 조건
2-8°C
수용성
Totally miscible
산도 계수 (pKa)
-1.61±0.70(Predicted)
물리적 상태
liquid
Merck
13,7423
BRN
8323501
EPA
Phosphamidon (13171-21-6)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T+,N
위험 카페고리 넘버 24-28-50/53-68
안전지침서 23-36/37-45-60-61
유엔번호(UN No.) 3018
WGK 독일 3
RTECS 번호 TC2800000
위험 등급 6.1(a)
포장분류 II
HS 번호 29241200
유해 물질 데이터 13171-21-6(Hazardous Substances Data)
독성 LD50 orally in rats: 24 mg/kg (Gaines)
기존화학 물질 KE-28556
유해화학물질 필터링 97-1-354;06-4-40
함량 및 규제정보 물질구분: 유독물질; 혼합물(제품)함량정보: 포스파미돈 및 이를 1% 이상 함유한 혼합물
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H300 삼키면 치명적임 급성 독성 물질 - 경구 구분 1,2 위험 P264, P270, P301+P310, P321, P330,P405, P501
H311 피부와 접촉하면 유독함 급성 독성 물질 - 경피 구분 3 위험 P280, P302+P352, P312, P322, P361,P363, P405, P501
H341 유전적인 결함을 일으킬 것으로 의심됨 (노출되어도 생식세포 유전독성을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재) 생식세포 변이원성 물질 구분 2 경고 P201,P202, P281, P308+P313, P405,P501
H410 장기적 영향에 의해 수생생물에 매우 유독함 수생 환경유해성 물질 - 만성 구분 1 경고 P273, P391, P501
예방조치문구:
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P312 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P301+P310 삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P501 ...에 내용물 / 용기를 폐기 하시오.

포스파미돈 C화학적 특성, 용도, 생산

개요

Types of phosphamidon formulations include soluble liquid, suspension concentrate and emulsifiable concentrate, ULV liquid, and 10% granules Phosphamidon is a pale yellow to colourless oily liquid with a faint odour. It is miscible with water and is soluble in aromatic hydrocarbons. Technical phosphamidon is a pale yellow to colourless oily liquid with a faint odour. It consists of a mixture of (Z)-isomer and (E)-isomer in the approximate proportion of 70:30. It decomposes on heating and releases highly toxic fumes such as phosphorus oxides, hydrogen chloride, and nitrogen oxides. Phosphamidon reacts and gets rapidly hydrolysed by alkalis and decomposes on heating or on burning, producing highly toxic fumes. It attacks metals such as iron, tin, and aluminium. It is used as a broad-spectrum insecticide and acaricide for the control of pests and vectors on crops like sugarcane, rice, citrus orchards, and cotton.

화학적 성질

Phosphamidon is a pale yellow to colorless oily liquid with a faint odor. It is miscible with water and is soluble in aromatic hydrocarbons. Phosphamidon decomposes on heating and releases highly toxic fumes, such as phosphorus oxides, hydrogen chloride, and nitrogen oxides. It reacts with bases (hydrolysis) and attacks metals such as iron, tin, and aluminium. Phosphamidon should be handled by trained personnel wearing protective clothing. Phosphamidon is used as a broad-spectrum insecticide and acaricide for the control of pests and vectors on crops like sugar cane, rice, citrus orchards, and cotton. Occupational exposures to phosphamidon occur among factory workers involved in synthesizing formulation and dispensing spray operations. Human exposures also occur among crop harvesters and in vector control operations.

화학적 성질

Phosphamidon is a pale yellow oily liquid

용도

Insecticide used to control sap-feeding insects and other pests in a wide variety of crops

용도

Phosphamidon is used to control sucking and boring insects and mites in a very wide range of crops and in forestry applications.

용도

Insecticide.

일반 설명

Pale yellow oily liquid with a faint odor. Used as an insecticide for citrus, cotton, and deciduous fruit and nuts. and as an acaricide.

공기와 물의 반응

Water soluble. Hydrolyzed by alkali with a half-life at 73°F of 13.8 days at pH 7 and 2.2 days at pH 10 .

반응 프로필

PHOSPHAMIDON is corrosive to iron, tin and aluminum. Incompatible with alkaline preparations and should not be mixed with copper oxychloride, captan, folpet or sulfur.

건강위험

PHOSPHAMIDON is extremely toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 150-lb person. It is a cholinesterase inhibitor.

건강위험

Phosphamidon is readily absorbed from the gastrointestinal tract, through the intact skin, and by inhalation of spray mists and dusts. Prolonged exposures to phosphamidon cause adverse effects and impairment on the respiratory, myocardial, and neuromuscular transmission in animals and humans. Phosphamidon does not cause delayed peripheral neuropathy in hens. The symptoms of poisoning include, but are not limited to, nausea, vomiting, diarrhea, abdominal cramps, headache, dizziness, eye pain, blurred vision, constriction or dilation of the pupils, tears, salivation, sweating, and confusion. Prolonged period of exposures to phosphamidon cause incoordination, slurred speech, loss of refl exes, weakness, fatigue, involuntary muscle contractions, twitching, tremors of the tongue or eyelids, and eventually paralysis of the body extremities and the respiratory muscles, involuntary defecation or urination, psychosis, irregular heart beat, unconsciousness, convulsions, coma, respiratory failure or cardiac arrest leading to death. Phosphamidon has caused clastogenic effects in the bone marrow cells of rats and mice. However, the studies are found to be inadequate to arrive at meaningful conclusions about phosphamidon as a human carcinogen and no data are available. The ADI for phosphamidon has been reported as 0.0005 mg/kg body weight. (ADI: acceptable daily intake is an estimate of the amount of a pesticide, expressed on a body weight basis, which can be ingested daily over a lifetime without appreciable health risk.)

화재위험

(Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Heat above 320F may cause decomposition and evolution of highly toxic fumes of phosphorus oxides and chlorides. Hydrolyzes in alkali. Stable in neutral and acid media. Hydrolyzes in alkali.

잠재적 노출

This material is used as an insecticide on citrus, cotton, and deciduous fruit and nuts. It is also an acaricide.

환경귀착

Chemical/Physical. Emits toxic fumes of chlorine, phosphorus and nitrogen oxides when heated to decomposition (Sax and Lewis, 1987)

신진 대사 경로

The metabolism of phosphamidon has been reviewed by Geissbuhler et al. (1971) and Beynon et al. (1973). Technical phosphamidon consists of two stereochemical isomers in the E:Z ratio of ca. 3:7. The Z-isomer has the greater insecticidal activity. It is important to note that in the case of phosphamidon the isomer with the phosphate ester function trans to the amide group is assigned the Z configuration due to the priority of chlorine, whereas in the case of mevinphos, monocrotophos and dicrotophos it is assigned the E configuration. In all four compounds, the isomers with this configuration (also referred to as the cis-crotonamide or crotonate structure) have the greater insecticidal activities. It is a systemic insecticide which is rapidly translocated in the plant via the xylem. Phosphamidon is rapidly degraded in the environment, the major routes being via N-de-ethylation and cleavage of the P-O-vinyl function. The resultant N,N-diethyl-2-chloroacetoacetamide or N-ethyl-2-chloroacetoacetamide are then degraded via dechlorination and hydrolysis, ultimately to give acetone, diethylamine and ethylamine. Conjugated metabolites have not been identified.

신진 대사

The major routes of degradation are oxidative dealkylation of the amide group and hydrolysis of the vinyl phosphate ester bond. Dechlorination also occurs. In soils, DT50 is 7–25 d depending upon the soil type.

운송 방법

UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Toxicity evaluation

The acute oral LD50 for rats is 17.9–30 mg/kg. Inhalation LC50 (4 h) for rats is about 0.18 mg/L air. NOEL (2 yr) for rats is 1.25 mg/kg b.w. daily. ADI is 0.5 μg/kg b.w. Phosphamidon administered in animals is rapidly metabolized, and 85–90% of the dose is excreted within 24 h almost all in the urine.

Degradation

Phosphamidon is rapidly hydrolysed by alkali (PM) but it is relatively stable at neutral and acidic pH values. In alkaline solution, the compound is hydrolysed to N,N-diethyl-2-chloroacetoacetamide (2) and dimethyl phosphate (3) (Anliker and Beringer, 1971). There was apparently no attack on the P-O-Me bond to give the desmethyl compound. In acidic solution compound 2 was hydrolysed to give chloroacetone (4), diethylamine (5) and C02. In alkaline solution 2 was dechlorinated and hydrolysed to acetone (6), acetic acid (7) and glycolic acid diethylamide (8). These pathways are shown in Scheme 1.

비 호환성

Compounds of the carboxyl group react with all bases, both inorganic and organic (i.e., amines) releasing substantial heat, water and a salt that may be harmful. Incompatible with arsenic compounds (releases hydrogen cyanide gas), diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides (releasing heat, toxic and possibly flammable gases), thiosulfates and dithionites (releasing hydrogen sulfate and oxides of sulfur). Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Strong oxidizers may cause release of toxic phosphorus oxides. Organophosphates, in the presence of strong reducing agents such as hydrides, may form highly toxic and flammable phosphine gas. Keep away from alkaline materials. Attacks metals, such as aluminum, iron, tin.

폐기물 처리

Small quantities may be treated with alkali followed by landfill disposal. Large quantities should be incinerated with effluent gas scrubbing. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

포스파미돈 준비 용품 및 원자재

원자재

준비 용품


포스파미돈 공급 업체

글로벌( 0)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점

포스파미돈 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved