4-메틸설포닐페닐아세트산
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4-메틸설포닐페닐아세트산 속성
- 녹는점
- 136-140 °C(lit.)
- 끓는 점
- 324.37°C (rough estimate)
- 밀도
- 1.4230 (rough estimate)
- 굴절률
- 1.6000 (estimate)
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 3.90±0.10(Predicted)
- 색상
- 흰색에서 연한 노란색
- 수용성
- 근소한
- BRN
- 2646649
- CAS 데이터베이스
- 90536-66-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
4-메틸설포닐페닐아세트산 C화학적 특성, 용도, 생산
화학적 성질
yellow to beige-brown crystalline powder용도
4-(Methylsulfonyl)phenylacetic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.제조 방법
synthesis of 4-(Methylsulfonyl)phenylacetic acid: 1-(4-Methanesulfonyl-phenyl)-ethanone (20 mmol), morpholine (60 mmol) and elemental sulfur (40 mmol) were added in a round-bottom flask and refluxed for 2 h at 398 K. A 3N solution of NaOH (20 ml) was then added, and the reaction mixture refluxed for an additional 30 min. After cooling, the mixture was filtered and the filtrate was acidified with HCl to pH 6. The solution was again filtered off and washed with ethyl acetate. The resulting aqueous fraction was finally acidified with diluted HCl, to yield the pure product as a white solid. Crystals suitable for X-ray analysis were obtained by slow evaporation of an ethanol/water (1:1 v/v) solution.주요 응용
4-(Methylsulfonyl)phenylacetic Acid is an intermediate used to prepare heterocyclic diaryl compounds as selective COX-2 inhibitors. It is also used to synthesize hydroxyfuranones as antioxidants and antiinflammatory agents.4-메틸설포닐페닐아세트산 준비 용품 및 원자재
원자재
2-(4-methylsulfanylphenyl)acetaldehyde
4-Methylsulphonylacetophenone
메틸2-(4-(메틸술포닐)페닐)아세테이트
4-Methylthiophenylacetic acid
1-(BROMOMETHYL)-4-(METHYLSULFONYL)BENZENE
4'-Methylthioacetophenone
4-(메틸티오)벤즈알데히드
준비 용품
4-메틸설포닐페닐아세트산 공급 업체
글로벌( 339)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| sgtlifesciences pvt ltd | +8617013299288 |
dj@sgtlifesciences.com | China | 12382 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 |
cbc@coresyn.com | China | 9991 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5882 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 |
bj1@bj-chem.com | China | 299 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
4-메틸설포닐페닐아세트산 관련 검색:
2-히드록시페닐아세트산 4-메톡시페닐초산 4-히드록시페닐아세트산 아세트산(빙초산) 페닐초산
DIMETHYL PYRIDINE-2,5-DICARBOXYLATE
Methyl 2-methylnicotinate
4-(METHYLSULFONYL)PHENYLACETONITRILE
Etoricoxib Impurity 18
Phenethyl phenylacetate
2-Methylphenylacetic acid
Etoricoxib
Etoricoxib Impurity 15
(Z)-1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethanone oxime
Etoricoxib Impurity 31
Etoricoxib iMpurity 1
Etoricoxib IMpurity
Etoricoxib Impurity 7