삼브롬화인
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삼브롬화인 속성
- 녹는점
- -41.5 °C (lit.)
- 끓는 점
- 175 °C (lit.)
- 밀도
- 2.88 g/mL at 20 °C (lit.)
- 증기 밀도
- 9.3 (vs air)
- 증기압
- 0.27 psi ( 54 °C)
- 굴절률
- n
20/D 1.697(lit.)
- 인화점
- 172.9°C
- 저장 조건
- Store below +30°C.
- 용해도
- soluble in Ether,Acetone,Chloroform
- 물리적 상태
- 액체
- Specific Gravity
- 2.88
- 색상
- 투명하거나 약간 흐릿함 무색 내지 노란색 또는 연한 갈색
- 냄새
- 자극적인 냄새
- 수용성
- 물과 반응
- 어는점
- -40℃
- 감도
- Moisture Sensitive
- Merck
- 14,7357
- BRN
- 3903060
- Dielectric constant
- 3.9(20℃)
- 안정성
- 안정적이지만 물과 격렬하게 반응합니다. 습기, 강염기, 강산화제, 반응성 금속, 산, 알코올과 호환되지 않습니다.
- InChIKey
- IPNPIHIZVLFAFP-UHFFFAOYSA-N
- LogP
- 2.394 (est)
- CAS 데이터베이스
- 7789-60-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | C | ||
---|---|---|---|
위험 카페고리 넘버 | 34-37-40-14-67 | ||
안전지침서 | 26-45-36/37-36/37/39 | ||
유엔번호(UN No.) | UN 3264 8/PG 2 | ||
WGK 독일 | 2 | ||
RTECS 번호 | TH4460000 | ||
F 고인화성물질 | 21 | ||
TSCA | Yes | ||
HS 번호 | 2812 90 00 | ||
위험 등급 | 8 | ||
포장분류 | II | ||
유해 물질 데이터 | 7789-60-8(Hazardous Substances Data) | ||
기존화학 물질 | KE-28722 |
삼브롬화인 C화학적 특성, 용도, 생산
화학적 성질
Phosphorus tribromide is a colourless liquid(possibly hazy) with the formula PBr3. It fumes in air due to hydrolysis and has a penetrating odour. It is widely used in the laboratory for the conversion of alcohols toalkyl bromides.Phosphorus tribromide (PBr3) is commonly used in Hell-Volhard-Zelinsky halogenation for the α-bromination of carboxylic acids to form the corresponding acyl bromide. It is also useful for the conversion of primary and secondary alcohols to alkyl bromides.
용도
Phosphorus tribromide is used mainly for the conversion of alcohols to alkyl bromides and it is used in tests for skin corrosivity. It is used for alkene preparation and it act as a lewis base and a lewis acid. Phosphorus tribromide is used in the manufacture of pharmaceuticals such as alprazolam, methohexital and fenoprofen.Phosphorus tribromide may be used as a reagent:
In a novel protocol for synthesizing 7-ethoxy-1-(p-ethylphenoxy)-3,7-dimethyl-2-octene, a synthetic juvenile hormone mimic of trans,trans,cis-10,11-epoxy-7-ethyl-3,11-dimethyltrideca-2,6-dienoate.
To synthesize 1,2,3-diazaphosphinane, 1,2,3-thiazaphosphinine and 1,2-azaphosphole bearing a chromone ring.
To synthesize 1-Bromoundec-1-ene from 10-undecen-1-ol.
제조 방법
Phosphorus tribromide, PBr3, is most conveniently prepared by reaction between liquid bromine and a solution of white phosphorus in PBr3. In most of its reactions, the tribromide resembles the trichloride although the former has been much less studied and in some cases the products seem to be more complex.화학 반응
Silyl phosphites such as (EtO)2POSiMe3 and (Et3SiO)3P are known. The latter compound can be prepared in 30% yield by reacting phosphorus tribromide with an organosilane in the presence of zinc chloride. Esters of the former type can be made by reaction.3Et3SiO+PBr3–-(Et3SiO)3+3RBr
Et3SiONa+(EtO)2PCl–-(EtO)2POSiEt3+NaCl)
일반 설명
A colorless fuming liquid with a pungent odor. Corrosive to metals and tissue. Boiling point 347°F (175°C). Freezing point -40°F (-40°C).공기와 물의 반응
Fumes in air. Decomposed by water to form phosphoric acid and hydrobromic acid. Reaction with warm water is very rapid and may be violent [Mellor v.8. 1032 1940].반응 프로필
Phosphorus tribromide reacts with oxidizing agents to generate heat and products that may be flammable, combustible, or otherwise reactive; the reactions may be violent. Forms complexes with potassium or sodium metal that explode when shocked. Drop wise addition to 3-phenylpropanol caused an explosion when stirring of the mixture was discontinued [Chem. Brit., 1974, 10, 101-102].건강위험
Inhalation causes severe irritation of nose, throat, and lungs. Ingestion causes burns of mouth and stomach. Contact with eyes or skin causes severe burns.Safety Profile
Probably highly toxic. A corrosive irritant to the eyes, skin, and mucous membranes. Wdl react with water, steam, or acids to produce heat, toxic and corrosive fumes. Violent reaction or ignition with calcium hydroxide + sodium carbonate, phenylpropanol, sulfuric acid, oleum, fluorosulfuric acid, chlorosulfuric acid, 1,1,1 -tris(hydroxymethyl)methane, water, potassium, sodium, RuO4. When heated to decomposition it emits very toxic fumes of Brand POx. See also PHOSPHIDES and BROMIDES.Purification Methods
It is decomposed by moisture, it should be kept dry and is corrosive. Purify it by distillation through an efficient fractionating column [see Whitmore & Lux J Am Chem Soc 54 3451] in a slow stream of dry N2, i.e. under strictly dry conditions. [Gay & Maxson Inorg Synth II 147 1946, Org Synth Col Vol II 358 1943.] Dissolve it in CCl4, dry it over CaCl2, filter and distil it. Store it in sealed ampoules under N2 and keep it away from light. HARMFUL VAPOURS.삼브롬화인 준비 용품 및 원자재
원자재
준비 용품
3-(3-Hydroxyphenyl)-DL-alanine
6-플루오로-4-(트리플루오로메틸)퀴놀린-2-아민
4-BROMO-TETRAHYDROPYRAN
4-TERT-BUTYLCYCLOHEXANECARBOXYLIC ACID
2-(2-FLUORO-PHENYL)-ETHANESULFONYL CHLORIDE
3-브로모-사이클로펜트-2-에놀
Tetrahydropyranyl-4-acetic acid
3,3,3-Trifluoropropionic acid
4-BROMO-6-(TRIFLUOROMETHYL)PYRIMIDINE
TETRAHYDRO-2H-PYRAN-4-YLACETYL CHLORIDE
1-(2-에톡시에틸)피페라진
사이클로헥실아민 히드로브롬화물
3,5-DIMETHOXYPHENYLACETONITRILE
1-브로모-2-플로로에탄
GUANETHIDINE SULFATE
3,5-DIMETHOXYBENZYL BROMIDE
2-(4-FLUORO-페닐)-에탄술포닐염화물
N-(2-BROMO-3-PYRIDINYL)ACETAMIDE
(4-FLUORO-BENZYL)-METHYL-AMINE
4-(Trifluoromethyl)quinoline-2-carbohydrazide ,97%
(6-Fluoro-4-(trifluoromethyl)quinolin-2-yl)methanol ,97%
Ethyl 6-fluoro-4-(trifluoromethyl)quinoline-2-carboxylate ,97%
1-(2-Methoxyethyl)hydrazine
2-브로모-6-플루오로-4-(트리플루오로메틸)퀴놀린
2-하이드록시-5-니트로벤질브로마이드
2-(4-CHLORO-PHENYL)-ETHANESULFONYL CHLORIDE
5-ACETAMIDO-2-BROMOPYRIDINE
2-METHOXY-5-(2'-ETHYLHEXYLOXY)BENZENE-1&
2-(1,5-Dimethyl-1H-pyrazol-3-yl)acetonitrile ,97%
(4-(트리플루오로메틸)퀴놀린-2-일)메탄올
2-Bromo-3-nitropyridine
2-(2-클로로-페닐)-에탄설포닐클로라이드
2-BROMO-4-(TRIFLUOROMETHYL)PYRIMIDINE
4-(트리플루오로메틸)퀴놀린-2-아민
5-Bromomethyl-1,3-dimethyl-1H-pyrazole ,97%
2-브로모-4-(트리플루오로메틸)퀴놀린
브로모메틸시클로핵산
(2-FLUOROBENZYL)메틸아민
4-TRIFLUOROMETHYL-QUINOLINE-2-CARBOXYLIC ACID
2-브로모에틸에틸에테르
삼브롬화인 공급 업체
글로벌( 418)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Yancheng Longshen Chemical Co.,Ltd. | +86-0515-88706880; +8618352073383 |
sales@longshenchem.com | China | 79 | 55 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12446 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5882 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9357 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8820 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
삼브롬화인 관련 검색:
테트라뷰틸포스포니움 브롬화물 브로민화 알루미늄, 무수물 인 옥시브롬화인 비스(트라이뷰틸주석) 옥사이드 트라이뷰틸포스핀 삼브롬화인
2,2,2-Tribromoethanol
Tribromoacetaldehyde
VANADIUM(III) ACETYLACETONATE
Triethylborane
Sodium acetate trihydrate
Sodium triacetoxyborohydride
Trimethylsilylacetylene
Trimethylsilyl trifluoromethanesulfonate
Pyridinium tribromide
Potassium trifluoromethanesulfonate
Iodotrimethylsilane