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칼슘 카르복시메틸 셀룰로오즈

칼슘 카르복시메틸 셀룰로오즈
칼슘 카르복시메틸 셀룰로오즈 구조식 이미지
카스 번호:
9050-04-8
한글명:
칼슘 카르복시메틸 셀룰로오즈
동의어(한글):
칼슘CM-셀룰로오즈;칼슘셀룰로오즈글리콜산;칼슘카르복시메틸셀룰로오즈;칼슘카르복시메틸셀룰로오즈(CALCIUMCARBOXYMETHYLCELLULOSE)
상품명:
CARBOXYMETHYLCELLULOSE CALCIUM (1.5 G) (AS)
동의어(영문):
ecg505;D03400;hylon600;CMCCalcium;calciumcm-cellulose;calciumcelluloseglycolate;Carmellose calcium (jp15);Calciam carboxymethylceUulose;carboxyMethyl cellose calciuM;CALCIUMCARBOXYLMETHYLCELLULOSE
CBNumber:
CB8500399
분자식:
C23H30ClN3O
포뮬러 무게:
399.9568
MOL 파일:
9050-04-8.mol

칼슘 카르복시메틸 셀룰로오즈 속성

용해도
Practically insoluble in acetone, chloroform, ethanol (95%), toluene, and ether. Insoluble in water, but swells to form a suspension.

안전

칼슘 카르복시메틸 셀룰로오즈 C화학적 특성, 용도, 생산

화학적 성질

DS 0.5-0.7

화학적 성질

Carboxymethylcellulose calcium occurs as a white to yellowishwhite, hygroscopic, odorless powder.

용도

Pharmaceutic aid (tablet disintegrant).

생산 방법

Cellulose, obtained from wood pulp or cotton fibers, is carboxymethylated, followed by conversion to the calcium salt. It is then graded on the basis of its degree of carboxymethylation and pulverized.

Pharmaceutical Applications

The main use of carboxymethylcellulose calcium is in tablet formulations, where it is used as a binder, diluent, and disintegrant. Although carboxymethylcellulose calcium is insoluble in water, it is an effective tablet disintegrant as it swells to several times its original bulk on contact with water. Concentrations up to 15% w/w may be used in tablet formulations; above this concentration, tablet hardness is reduced.
Carboxymethylcellulose calcium is also used in other applications similarly to carboxymethylcellulose sodium; for example, as a suspending or viscosity-increasing agent in oral and topical pharmaceutical formulations. Carboxymethylcellulose calcium is also used in modern wound dressings for its water absorption, retention and hemostatic properties.

Safety

Carboxymethylcellulose calcium is used in oral and topical pharmaceutical formulations, similarly to carboxymethylcellulose sodium, and is generally regarded as a nontoxic and nonirritant material. However, as with other cellulose derivatives, oral consumption of large amounts of carboxymethylcellulose calcium may have a laxative effect.

저장

Carboxymethylcellulose calcium is a stable, though hygroscopic material. It should be stored in a well-closed container in a cool, dry place.

Regulatory Status

Included in the FDA Inactive Ingredients Database (oral, capsules and tablets). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

칼슘 카르복시메틸 셀룰로오즈 준비 용품 및 원자재

원자재

준비 용품


칼슘 카르복시메틸 셀룰로오즈 공급 업체

글로벌( 21)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21935 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20676 55
Spectrum Chemical Manufacturing Corp. 021-67601398,18616765336,QQ:3003443155
021-57711696 mkt@spectrumchina.net China 9690 60
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 sj_scrc@sinopharm.com China 9851 79
BOC Sciences
info@bocsci.com United States 10507 65
Wuhan HongxinKang Fine Chemical Co., Ltd. 18672345876
027-59721024 richer3322@163.com China 1859 58
JinJinLe Chemical 10106090
jjlechem@163.com China 9454 58
Wuhan Netcom Electronic Commerce Limited 18029749525
0757-88210752 2355935187@ycphar.com China 4920 58
Xi'an boliante Chemical Co., Ltd. 17719597442
- 3570451756@qq.com China 3022 58
Shaanxi Pioneer Biotech Co., Ltd. 029-8438-5017 17792750529
029-8438-5017 sales3@pioneerbiotech.com China 2850 55

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