NU7026
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NU7026 속성
- 녹는점
- 267-269 °C(Solv: methanol (67-56-1); water (7732-18-5))
- 끓는 점
- 459.9±45.0 °C(Predicted)
- 밀도
- 1.330
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 60℃에서 3mg/mL, 가용성
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 0.49±0.20(Predicted)
- 색상
- 갈색을 띤 노란색
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| WGK 독일 | 3 |
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| 그림문자(GHS): |
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| 신호 어: | Danger | ||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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NU7026 C화학적 특성, 용도, 생산
용도
NU7026 has been used:- as a DNA-dependent protein kinase (DNA-PK) inhibitor, to pre-treat colon cancer cell
- in kinase inhibitor experiments for treating zygotes with visible pronuclei post 20 h-human chorionic gonadotropin (hCG)
- to determine its influence on cytotoxicity of dibenzo[def,p]chrysene on HepG2 cells
생물학적 활성
ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC 50 values are 0.23, 13.0, > 100 and > 100 μ M for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair.Biochem/physiol Actions
Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).NU7026 준비 용품 및 원자재
원자재
아세틸모르폴린
METHYL 1-HYDROXY-2-NAPHTHOATE
1-(1-hydroxynaphthalen-2-yl)-3-Morpholin-4-ylpropane-1,3-dione
준비 용품
NU7026 공급 업체
글로벌( 104)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29220 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
| Young Lively PharminBlock Co.,Ltd | +undefined18600731423 |
jason_gao@yl-pharminblock.com | China | 1944 | 58 |