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FK 888

FK 888 구조식 이미지

카스 번호:: 138449-07-7

상품명:: FK 888

동의어(영문):: FK 888;FK888 hydrate;N(2)-(4-Hydroxy-1-(1-methyl-1H-indol-3-yl)carbonyl-L-prolyl)-N-methyl-N-phenylmethyl-3-(2-naphthyl)-L-alaninamide;(4R)-4-Hydroxy-1-[(1-methyl-1H-indol-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide;L-Alaninamide, (4R)-4-hydroxy-1-((1-methyl-1H-indol-3-yl)carbonyl)-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-;L-Alaninamide, trans-4-hydroxy-1-((1-methyl-1H-indol-3-yl)carbonyl)-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-;N2-[(4R)-4-hydroxyl-1-(1-methyl-1H-indol-3-yl)carbonyl-L-prolyl]-N-methyl-N-phenylmethyl-3-(2-naphthyl)-L-alaninamide hydrate;(4R)-4-Hydroxy-1-[(1-methyl-1H-indol-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide hydrate

CBNumber:: CB8785831

분자식:: C36H36N4O4

포뮬러 무게:: 588.7

MOL 파일:: 138449-07-7.mol

속성

안전

용도

공급 업체 22

FK 888 속성

끓는 점: 901.9±65.0 °C(Predicted)

밀도: 1.26±0.1 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMSO: ≥13mg/mL

물리적 상태: 가루

산도 계수 (pKa): 13.01±0.40(Predicted)

색상: 흰색에서 황갈색까지

optical activity: [α]/D -135 to -145°, c = 1 in methanol

안전

WGK 독일	3

FK 888 C화학적 특성, 용도, 생산

용도

FK 888 is a neurokinin NK1 receptor antagonist, which is active both in vivo and in vitro.

생물학적 활성

Selective, high affinity tachykinin NK 1 receptor antagonist (K i = 0.69 nM) that displays 320-fold selectivity for human over rat NK 1 receptors. Inhibits substance P-induced contraction of isolated guinea pig trachea (IC 50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration.

FK 888 준비 용품 및 원자재

원자재

준비 용품

FK 888 공급 업체

글로벌( 22)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4030	58
RD International Technology Co., Limited	18988968278	sales@ubiochem.com	China	9146	58

FK 888 관련 검색:

그라민 3-(NAPHTHALEN-2-YL)PROPAN-1-AMINE 2-NAPHTHALEN-2-YL-ETHYLAMINE (1-Methyl-1H-indol-3-yl)-methylamine 1H-PYRROLE-3-METHANAMINE, 1-METHYL- 1H-Indole-3-carboxamide(9CI) FK 888 1-Methylindole-3-carboxaldehyde