그라민
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그라민 속성
- 녹는점
- 132-134 °C (lit.)
- 끓는 점
- 295.23°C (rough estimate)
- 밀도
- 1.0715 (rough estimate)
- 굴절률
- 1.5500 (estimate)
- 인화점
- 167 °C
- 저장 조건
- Refrigerator (+4°C)
- 용해도
- almost transparency in Methanol
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 17.00±0.30(Predicted)
- 색상
- 베이지색
- 수용성
- 실질적으로 불용성
- Merck
- 14,4533
- BRN
- 140521
- LogP
- 2.177 (est)
- CAS 데이터베이스
- 87-52-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
| 위험품 표기 | C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 34 | ||
| 안전지침서 | 45-36/37/39-26 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | NL7525000 | ||
| HS 번호 | 29339900 |
그라민 C화학적 특성, 용도, 생산
화학적 성질
?3-(Dimethylaminomethyl)indole [87-52-5], gramine, C11H14N2, Mr 174.25, mp 138 – 139 ℃, forms colorless needles. The compound is soluble in ethanol, diethyl ether, and chloroform and insoluble in water. It can be synthesized from indole by the Mannich reaction with dimethyl-amine and formaldehyde. Gramine is used to synthesize D,L-tryptophan, the plant growth regulators indole-3-acetic acid and indole-3-butanoic acid as well as the intermediate tryptamine.용도
Reactant for preparation of:- Dopamine D2 receptor antagonists
- Anti-malarial drugs
- 5-indolyl-Mannich bases
- Proliferation inhibitors
- Inhibitors of human mast cell chymase
- Preparation of DL-tryptophan
- Potential detoxification inhibitors of the crucifer phytoalexin brassinin
- 3-vinylindoles
- Serotonin 5-HT6 receptor ligand templates
- Selective protein kinase c delta (PKCδ) down regulators
일반 설명
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KGPurification Methods
Crystallise gramine from diethyl ether, ethanol or acetone. It sublimes at 59o/0.001mm. The hydrochloride crystallises from EtOH/Et2O with m 190.5-191.0o(dec). [Culvenor et al. Aust J Chem 17 1301 1964, Beilstein 22 III/IV 4302, 22/10 V 25.]그라민 준비 용품 및 원자재
원자재
인돌
디메틸아민
Methanamine, 1-ethoxy-N,N-dimethyl-
GRAMINE, N-OXIDE
N,N-dimethyl-1H-indole-3-carboxamide
ESCHENMOSER'S SALT
Indole-3-carboxaldehyde
N,N,N,N-테트라메틸메틸렌디아민
포르말린
우라실
준비 용품
그라민 공급 업체
글로벌( 373)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 16799 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |