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1-클로로-3,4-디니트로벤젠

1-클로로-3,4-디니트로벤젠
1-클로로-3,4-디니트로벤젠 구조식 이미지
카스 번호:
610-40-2
한글명:
1-클로로-3,4-디니트로벤젠
동의어(한글):
1-클로로-3,4-디니트로벤젠;1-클로로-3,4-다이나이트로벤젠
상품명:
3,4-Dinitrochlorobenzene
동의어(영문):
3,4-DINITROCHLOROBENZENE;4-Chloro-1,2-dinitrobenzen;3,4-Dinitrochlorobenzene>1-CHLORO-3,4-DINITROBENZENE;4-CHLORO-1,2-DINITROBENZENE;1,2-Dinitro-4-chlorobenzene;1,2-Dinitro-5-chlorobenzene;Benzene, 4-chloro-1,2-dinitro-;1-Chloro-3,4-dinitrobenzene, 92%+;1-Chloro-3,4-dinitrobenzene,90%,tech.
CBNumber:
CB9691894
분자식:
C6H3ClN2O4
포뮬러 무게:
202.55
MOL 파일:
610-40-2.mol

1-클로로-3,4-디니트로벤젠 속성

녹는점
40-41 °C
끓는 점
16 °C (4 mmHg)
밀도
1.687 g/mL at 25 °C(lit.)
굴절률
n20/D 1.587(lit.)
인화점
>230 °F
저장 조건
0-10°C
물리적 상태
Oily Liquid After Melting
색상
Yellow-brown
수용성
insoluble
BRN
521564
CAS 데이터베이스
610-40-2(CAS DataBase Reference)
NIST
Benzene, 4-chloro-1,2-dinitro-(610-40-2)
EPA
Benzene, 4-chloro-1,2-dinitro- (610-40-2)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T,N
위험 카페고리 넘버 23/24/25-33-50/53
안전지침서 28-36/37-45-60-61-28A
유엔번호(UN No.) UN 3441 6.1/PG 2
WGK 독일 3
TSCA Yes
위험 등급 6.1
포장분류 II
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H300 삼키면 치명적임 급성 독성 물질 - 경구 구분 1,2 위험 P264, P270, P301+P310, P321, P330,P405, P501
H310 피부와 접촉하면 치명적임 급성 독성 물질 - 경피 구분 1,2 위험 P262, P264, P270, P280, P302+P350,P310, P322, P361, P363, P405, P501
H317 알레르기성 피부 반응을 일으킬 수 있음 피부 과민성 물질 구분 1 경고 P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H330 흡입하면 치명적임 급성 독성 물질 흡입 구분 1, 2 위험 P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H371 장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킬 수 있음(노출되어도 특정 표적장기 독성을 일으키지 않는다는 결정적인 노출경로가 있다면 노출경로를 기재) 특정 표적장기 독성 - 2회 노출 구분 2 경고 P260, P264, P270, P309+P311, P405,P501
H373 장기간 또는 반복 노출되면 장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킬 수 있음 특정 표적장기 독성 - 반복 노출 구분 2 경고 P260, P314, P501
H400 수생생물에 매우 유독함 수생 환경유해성 물질 - 급성 구분 1 경고 P273, P391, P501
H410 장기적 영향에 의해 수생생물에 매우 유독함 수생 환경유해성 물질 - 만성 구분 1 경고 P273, P391, P501
예방조치문구:
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P270 이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P272 작업장 밖으로 오염된 의복을 반출하지 마시오.
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P320 긴급히 (…) 처치를 하시오.
P330 입을 씻어내시오.
P391 누출물을 모으시오.
P304+P340 흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P405 밀봉하여 저장하시오.
P403+P233 용기는 환기가 잘 되는 곳에 단단히 밀폐하여 저장하시오.
P501 ...에 내용물 / 용기를 폐기 하시오.

1-클로로-3,4-디니트로벤젠 MSDS


1-Chloro-3,4-dinitrobenzene

1-클로로-3,4-디니트로벤젠 C화학적 특성, 용도, 생산

개요

Securinine is derived from the leaf of Securinega suffruticosa Rehd., which was first separated by V.I.?Murav’eva in 1956 . Securinega suffruticosa Rehd., a kind of subshrub plant, is widely distributed in temperate and subtropical regions . It has strong adaptability and can be planted in most parts of China. Moreover, it is rich in natural resources. Securinega suffruticosa Rehd. is a folk medicine whose root is the main component, with the effects of activating circulation, spleen, and stomach to treat rheumatism waist pain, limb numbness, infant malnutrition, and other diseases. The roots, stems, leaves, flowers, and skin of Securinega suffruticosa Rehd. contain alkaloids, in which securinine is the main ingredient.

화학적 성질

YELLOW-BROWN OILY LIQUID AFTER MELTING

물리적 성질

Appearance: yellow crystalline powder, slightly bitter. Solubility: soluble in anhydrous ethanol or chloroform, insoluble in water. Melting point: 139–140?°C Specific optical rotation: (D) ?1042°(C?=?1, EtOH).

역사

Securinine was first isolated by a Soviet scholar from the Wusuli region, but its chemical structure was separated and finally determined by Chinese scholars from local sources . The main structural feature is a tetracyclic compound containing an indolizine, pyrrole elidine, or quinolizine ring and an α, β-unsaturated pentahydrin ring whose basic structural skeleton type is as shown in what follows .
Owing to the complexity of the chemical reaction of securinine, reports on its chemical reactivity and structural modification have been relatively scarce since securinine was reported on in 1956. However, the research on chemical total synthesis and biological activities of securinine has made a certain amount of progress.
Securinine has a rigid molecular structure containing four rings and three chiral centers, which makes synthesis difficult. From 1974 to 1978, three research groups from Japan, the USA, and Canada studied the biosynthesis of securinine by feeding animals with isotope-labeled S. suffruticosa.

용도

This compound is a sensitizer.

Indications

Poliomyelitis sequela and facial paralysis, neurasthenia, hypotension, autonomic dysfunction, and others

Pharmacology

The pharmacological effect of securinine is mainly manifested as a central nervous system excitatory effect. As a GABA receptor inhibitor, it has an excitatory effect similar to that of strychnine on the spinal cord. A low dose of securinine can improve the excitability of brain reflection, while a high dose of securinine will cause febrile seizures, and at the same time securinine can strengthen the conditioned reflex of the cerebral cortex, shorten the latency period, and promote learning and memory capability , and so it is expected to be a promising drug for the treatment of Alzheimer’s disease.,
Securinine can improve the hematopoietic environment of patients with aplastic anemia, promote cell proliferation, have a synergistic anti-tumor effect in combination with cyclophosphamide (CTX), and can antagonize bone marrow suppression caused by CTX.?It has an inhibitory effect on cell proliferation of human leukocyte cell K562 and four other kinds of tumor cells.

Clinical Use

In recent years, securinine has been widely used in clinical practice, mainly for the treatment of polio sequelae and facial nerve palsy. It also has a certain effect on neurasthenia, hypotension and dizziness, tinnitus, and deafness caused by autonomic dysfunction. The nitrate and hydrochloride of left-handed securinine are mainly used clinically. In addition, securinine eye drops are found to have a remarkable effect on the treatment of herpes simplex keratitis through initial clinical observation.

1-클로로-3,4-디니트로벤젠 준비 용품 및 원자재

원자재

준비 용품


1-클로로-3,4-디니트로벤젠 공급 업체

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SIMAGCHEM CORP
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Career Henan Chemica Co
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0551-65418671
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18071025641 18071025641
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17705817739 +86-571-88938639
+86-571-88938652,+86-571- 88492614 info@dycnchem.com CHINA 52932 58
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