ChemicalBook
Chinese English Japanese Germany Korea

말레인산클로로페니라민

말레인산클로로페니라민
말레인산클로로페니라민 구조식 이미지
카스 번호:
113-92-8
한글명:
말레인산클로로페니라민
동의어(한글):
말레인산클로로페니라민;클로르페닐아민말산;클로르페닐아민말산
상품명:
Chlorpheniramine maleate
동의어(영문):
Haynon;alunex;piriex;Puermin;c-meton;ibioton;lorphen;piriton;teldrin;Histadur
CBNumber:
CB9142008
분자식:
C20H23ClN2O4
포뮬러 무게:
390.86
MOL 파일:
113-92-8.mol

말레인산클로로페니라민 속성

녹는점
130-135 °C (lit.)
알파
-1~+1°(D/20℃)(c=5,DMF)
밀도
1.1984 (rough estimate)
굴절률
1.6800 (estimate)
인화점
9℃
저장 조건
2-8°C
용해도
Freely soluble in water, soluble in ethanol (96 per cent)
물리적 상태
neat
수소이온지수(pH)
4.0~5.5 (10g/l, 25℃)
수용성
1-5 g/100 mL at 21 ºC
Merck
14,2180
InChIKey
DBAKFASWICGISY-BTJKTKAUSA-N
EPA
Chlorpheniramine maleate (113-92-8)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T,F
위험 카페고리 넘버 25-39/23/24/25-23/24/25-11
안전지침서 36/37/39-45-36/37-16
유엔번호(UN No.) UN 2811 6.1/PG 3
WGK 독일 3
RTECS 번호 US6504000
TSCA Yes
위험 등급 6.1(b)
포장분류 III
HS 번호 29333990
독성 LD50 orally in mice: 162 mg/kg (Smith)
기존화학 물질 KE-05616
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H225 고인화성 액체 및 증기 인화성 액체 구분 2 위험 P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 P264, P270, P301+P312, P330, P501
H370 장기(또는, 영향을 받은 알려진 모든 장기를 명시)에 손상을 일으킴(노출되어도 특정 표적장기 독성을 일으키지 않는다는 결정적인 노출경로가 있다면 노출경로를 기재) 특정 표적장기 독성 - 1회 노출 구분 1 위험 P260, P264, P270, P307+P311, P321,P405, P501
예방조치문구:
P210 열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
P260 분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P270 이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P311 의료기관(의사)의 진찰을 받으시오.
P330 입을 씻어내시오.
P301+P310 삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.

말레인산클로로페니라민 MSDS


Chlorphenamine hydrogen maleate

말레인산클로로페니라민 C화학적 특성, 용도, 생산

화학적 성질

White Solid

용도

An antagonist of the histamine H1-receptor

용도

Antihistaminic

상표명

Trimeton (Schering-Plough); Teldrin (GlaxoSmithKline).

일반 설명

Chlorpheniraminemaleate, (±)2-[p-chloro-α-[2-dimethylamino)ethyl]benzyl]pyridine bimaleate (Chlor-Trimeton), is a white crystallinepowder that is soluble in water (1:3.4), in alcohol(1:10), and in chloroform (1:10). It has a pKa of 9.2, and anaqueous solution has a pH between 4 and 5. Chlorination ofpheniramine in the para position of the phenyl ring increasespotency 10-fold with no appreciable change in toxicity.Most of the antihistaminic activity resides with thedextro isomer (see under “Dexchlorpheniramine Maleate” ).The usual dose is 2 to 4 mg 3 or 4 times a day. It has a halflifeof 12 to 15 hours.

일반 설명

Odorless white crystalline solid or white powder with a bitter taste. pH (2% aqueous solution) 5. pH (1% aqueous solution) 4-5.

공기와 물의 반응

Water soluble.

반응 프로필

A halogenated amine, ester. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

화재위험

Flash point data for Chlorpheniramine maleate are not available; however, Chlorpheniramine maleate is probably combustible.

Safety Profile

Poison by ingestion, intravenous, and subcutaneous routes. Experimental reproductive effects. Used as an antihistamine. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx.

Veterinary Drugs and Treatments

Antihistamines are used in veterinary medicine to reduce or help prevent histamine mediated adverse effects. Chlorpheniramine is one the more commonly used antihistamines in the cat for the treatment of pruritus. It may also be of benefit as a mild sedative in small animals due to its CNS depressant effects.

Dosage forms

4 to 6 mg PO q4–6h. Maximum daily dose is 24 mg for adults and children 12 years or older. Found frequently in combination with acetaminophen and pseudoephedrine.

말레인산클로로페니라민 준비 용품 및 원자재

원자재

준비 용품


말레인산클로로페니라민 공급 업체

글로벌( 434)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998
sales@czwytech.com CHINA 914 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 497 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8909 55
Rixing Chemical CO.,LTD
13237129059
- info@rixingchemi.com CHINA 229 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 567 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679
86-0551-65418697 info@tnjchem.com China 3000 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29954 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2941 58

말레인산클로로페니라민 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved