아크리딘
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아크리딘 속성
- 녹는점
- 106-109 °C
- 끓는 점
- 346 °C(lit.)
- 밀도
- 1,005 g/cm3
- 굴절률
- 1.7270 (estimate)
- 인화점
- 346°C
- 저장 조건
- Refrigerator
- 용해도
- 디옥산: 0.1 g/mL, 투명
- 산도 계수 (pKa)
- 5.58(at 20℃)
- 물리적 상태
- 결정성 분말
- 색상
- 노란색에서 황갈색
- pH 범위
- Green B uorescence (5.2) to violet B uorescence (6.6)
- 수용성
- 57.35mg/L(24℃)
- 최대 파장(λmax)
- 358nm, 392nm
- Merck
- 14,122
- BRN
- 120200
- 노출 한도
- OSHA: TWA 0.2 mg/m3
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- 주요 응용
- Organic light-emitting diode, photoresists, nanosensors, fuel cells, memory device, semiconductors, information storage device, liquid crystal displays, identification of product forgeries, inks, adhesives, textile, hair dyes, gene detection assay, staining cells, biosensors, detecting nucleic acids, proteins, antiHCV antibodies, antibacterial, antiamyloid agents, wound dressing materials, vaccines against infection, allergy and cancer
- InChIKey
- DZBUGLKDJFMEHC-UHFFFAOYSA-N
- LogP
- 3.400
- CAS 데이터베이스
- 260-94-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22-68-36/37/38 | ||
안전지침서 | 22-36-45-36/37/39-26 | ||
유엔번호(UN No.) | UN 2713 6.1/PG 3 | ||
WGK 독일 | 3 | ||
RTECS 번호 | AR7175000 | ||
TSCA | Yes | ||
위험 등급 | 6.1 | ||
포장분류 | III | ||
HS 번호 | 29333990 | ||
유해 물질 데이터 | 260-94-6(Hazardous Substances Data) | ||
독성 | LD50 s.c. in mice: 0.40 g/kg (Rubbo) |
아크리딘 C화학적 특성, 용도, 생산
화학적 성질
colourless to light yellow crystals용도
manufacture of dyes and intermediates; some dyes derived from it are used as antiseptics, e.g. 9-aminoacridine, acriflavine and proflavine. The hydrochloride has been used as reagent for cobalt, iron and zinc.정의
A colorless crystalline heterocyclic compound with three fused rings. Derivatives of acridine are used as dyes and biological stains.World Health Organization (WHO)
Acridine derivatives with antiseptic and disinfectant activity, including acriflavine, proflavine and euflavine, were formerly used in the treatment of infected wounds and burns. Such use has largely been discontinued on the grounds that safer and more effective alternatives are now available. Following demonstration of the mutagenic activity of proflavine in 1978 it was withdrawn from dental products in Denmark. Subsequently, euflavine was similarly withdrawn.일반 설명
Small colorless needle-like crystalline solid. Slightly soluble in hot water. Slightly denser than water. Contact may irritate skin, eyes, and mucous membranes. Sublimes before melting when heated. May be toxic by ingestion.공기와 물의 반응
Slightly soluble in hot water.반응 프로필
Acridine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. Burns to give toxic oxides of nitrogen.건강위험
Inhalation irritates respiratory system and causes sneezing, crying, and vomiting. Contact with liquid irritates eyes, skin, and mucous membranes. At high temperature and during sun exposure, damage to the cornea, skin, and mucous membranes may occur following the liberation of Acridine vapor.Safety Profile
Poison by ingestion, subcutaneous, and intravenous routes. Mutation data reported. A skin, eye, and mucous membrane irritant. When heated to decomposition it emits toxic fumes of NO,.잠재적 노출
Acridine and its derivatives are widely used in the production of dyestuffs, such as acriflavine, benzoflavine, and chrysaniline; and in the synthesis of pharmaceuticals; such as aurinacrine, proflavine, and rivanol. A constituent of coal tar, coal tar creosote; found in wastes from gas and tar plants and coke oven emissions. Incompatibilities: Strong acids, strong oxidizers.운송 방법
UN2713 Acridine, Hazard Class: 6.1; Labels: 6.1-Poisonous materialsPurification Methods
Acridine has been crystallised twice from *benzene/cyclohexane, or from aqueous EtOH, then sublimed, removing and discarding the first 25% of the sublimate. The remainder is again crystallised and sublimed, discarding the first 10-15% [Wolf & Anderson J Am Chem Soc 77 1608 1955]. Acridine can also be purified by crystallisation from n-heptane and then from ethanol/water after pre-treatment with activated charcoal, or by chromatography on alumina with pet ether in a darkened room. Alternatively, acridine can be precipitated as the hydrochloride from *benzene solution by adding HCl, after which the base is regenerated, dried at 110o/50mm, and recrystallised to constant melting point from pet ether [Cumper et al. J Chem Soc 4518 1962]. The regenerated free base may be recrystallised, chromatographed on basic alumina, then vacuum-sublimed and zone-refined. [Williams & Clarke, J Chem Soc, Faraday Trans 1 73 514 1977, Albert, The Acridines Arnold Press 1966.] It can exist in five crystalline forms and is steam volatile. It is a strong IRRITANT to skin and mucous membranes and can become a chronic irritant— handle it with CARE. [Beilstein 20/8 V 199.]비 호환성
Acridine and its derivatives are widely used in the production of dyestuffs, such as acriflavine, benzoflavine, and chrysaniline; and in the synthesis of pharmaceuticals; such as aurinacrine, proflavine, and rivanol. A constituent of coal tar, coal tar creosote; found in wastes from gas and tar plants and coke oven emissions. Incompatibilities: Strong acids, strong oxidizers.폐기물 처리
Incineration with nitrogen oxide removal from the effluent gas by scrubber, catalytic, or thermal device.아크리딘 준비 용품 및 원자재
원자재
아연
N-페닐안트라닐산
9(10H)-아크리돈
Benzaldehyde, 2-(phenylamino)-
2-아지도벤즈알데히드
10-옥시라토아크리딘-10-이움
카바진
9-아크리딘카르복실산
에틸페놀(2-)
2,2'-메틸렌디아닐린
디페닐요오도늄트리플루오로메탄설포네이트
2-니트로벤즈알레하이드
페닐붕산
준비 용품
아크리딘 공급 업체
글로벌( 190)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Wuhan Kemi-Works Chemical Co., Ltd. | +86-2785736489 +8618171418573 |
sales@kemiworks.com | China | 727 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9308 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Zhengzhou Yuanli Biological Technology Co., Ltd | 0086-371-67897895 |
info@zzyuanli.cn | CHINA | 136 | 58 |
Patience Biological Engineering (Shanghai)Co.,Ltd. | 13818903334 |
admin@pssh.com.cn | CHINA | 2 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12446 | 58 |
아크리딘 관련 검색:
C.I. 염료 황색 24 C.I. 색소 VI올ET 19 아크리딘 3,6-디아미노아크리딘 헤미황산염 디벤즈(A,J)아크리딘 페난트리딘 디벤즈(A,H)아크리딘
3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
7,8-BENZOQUINOLINE,alpha-Benzoquinoline,7,8-BENZOQUINOLINE 98%,1-Naphthoquinoline, 7,8-Benzoquinoline
CI 46025
9-Chloroacridine
6,9-Dichloro-2-methoxyacridine
9-ACRIDINECARBOXYLIC ACID HYDRATE
Mepacrine hydrochloride
9-HYDROXY-4-METHOXYACRIDINE
acridine,monohydrochlorid
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
ACRIDINE ORANGE