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Acridin Produkt Beschreibung

Acridine Struktur
260-94-6
CAS-Nr.
260-94-6
Bezeichnung:
Acridin
Englisch Name:
Acridine
Synonyma:
Akridin;NSC 3408;Acrydine;ACRIDINE;Aceridine;ACRIDINE 97%;Acridine, 98+%;9-Azaanthracene;10-Azaanthracene;Acridine, 98% 5GR
CBNumber:
CB9853399
Summenformel:
C13H9N
Molgewicht:
179.22
MOL-Datei:
260-94-6.mol

Acridin Eigenschaften

Schmelzpunkt:
106-109 °C
Siedepunkt:
346 °C(lit.)
Dichte
1,005 g/cm3
Brechungsindex
1.7270 (estimate)
Flammpunkt:
346°C
storage temp. 
Refrigerator
Löslichkeit
dioxane: 0.1 g/mL, clear
pka
5.58(at 20℃)
Aggregatzustand
Crystalline Powder
Farbe
Yellow to yellow-brown
Säure-Base-Indikators(pH-Indikatoren)
Green B uorescence (5.2) to violet B uorescence (6.6)
maximale Wellenlänge (λmax)
358nm, 392nm
Merck 
14,122
BRN 
120200
Stabilität:
Stable. Combustible. Incompatible with strong oxidizing agents.
Major Application
Organic light-emitting diode, photoresists, nanosensors, fuel cells, memory device, semiconductors, information storage device, liquid crystal displays, identification of product forgeries, inks, adhesives, textile, hair dyes, gene detection assay, staining cells, biosensors, detecting nucleic acids, proteins, antiHCV antibodies, antibacterial, antiamyloid agents, wound dressing materials, vaccines against infection, allergy and cancer
InChIKey
DZBUGLKDJFMEHC-UHFFFAOYSA-N
CAS Datenbank
260-94-6(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 22-68-36/37/38
S-Sätze: 22-36-45-36/37/39-26
RIDADR  UN 2713 6.1/PG 3
WGK Germany  3
RTECS-Nr. AR7175000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29333990
Toxizität LD50 s.c. in mice: 0.40 g/kg (Rubbo)
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
H341 Kann vermutlich genetische Defekte verursachen. Keimzellmutagenität Kategorie 2 Warnung P201,P202, P281, P308+P313, P405,P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P261 Einatmen von Staub vermeiden.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P501 Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Acridin Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R22:Gesundheitsschädlich beim Verschlucken.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

colourless to light yellow crystals

Verwenden

A quinoline derivative used as manufacturing dyes and as intermediate for antileishmanial agents. A catabolic product of carbamazepine (C175840) metabolite.

Verwenden

manufacture of dyes and intermediates; some dyes derived from it are used as antiseptics, e.g. 9-aminoacridine, acriflavine and proflavine. The hydrochloride has been used as reagent for cobalt, iron and zinc.

Definition

ChEBI: A polycyclic heteroarene that is anthracene in which one of the central CH groups is replaced by a nitrogen atom.

Definition

A colorless crystalline heterocyclic compound with three fused rings. Derivatives of acridine are used as dyes and biological stains.

Definition

acridine: A colourless crystallineheterocyclic compound, C12H9N; m.p.110°C. The ring structure is similarto that of anthracene, with threefused rings, the centre ring containinga nitrogen heteroatom. Severalderivatives of acridine (such as acridineorange) are used as dyes or biologicalstains.

Trademarks

Euflavin;Proflavin.

Weltgesundheitsorganisation (WHO)

Acridine derivatives with antiseptic and disinfectant activity, including acriflavine, proflavine and euflavine, were formerly used in the treatment of infected wounds and burns. Such use has largely been discontinued on the grounds that safer and more effective alternatives are now available. Following demonstration of the mutagenic activity of proflavine in 1978 it was withdrawn from dental products in Denmark. Subsequently, euflavine was similarly withdrawn.

Allgemeine Beschreibung

Small colorless needle-like crystalline solid. Slightly soluble in hot water. Slightly denser than water. Contact may irritate skin, eyes, and mucous membranes. Sublimes before melting when heated. May be toxic by ingestion.

Air & Water Reaktionen

Slightly soluble in hot water.

Reaktivität anzeigen

Acridine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. Burns to give toxic oxides of nitrogen.

Health Hazard

Inhalation irritates respiratory system and causes sneezing, crying, and vomiting. Contact with liquid irritates eyes, skin, and mucous membranes. At high temperature and during sun exposure, damage to the cornea, skin, and mucous membranes may occur following the liberation of Acridine vapor.

Sicherheitsprofil

Poison by ingestion, subcutaneous, and intravenous routes. Mutation data reported. A skin, eye, and mucous membrane irritant. When heated to decomposition it emits toxic fumes of NO,.

mögliche Exposition

Acridine and its derivatives are widely used in the production of dyestuffs, such as acriflavine, benzoflavine, and chrysaniline; and in the synthesis of pharmaceuticals; such as aurinacrine, proflavine, and rivanol. A constituent of coal tar, coal tar creosote; found in wastes from gas and tar plants and coke oven emissions. Incompatibilities: Strong acids, strong oxidizers.

Versand/Shipping

UN2713 Acridine, Hazard Class: 6.1; Labels: 6.1-Poisonous materials

läuterung methode

Acridine has been crystallised twice from *benzene/cyclohexane, or from aqueous EtOH, then sublimed, removing and discarding the first 25% of the sublimate. The remainder is again crystallised and sublimed, discarding the first 10-15% [Wolf & Anderson J Am Chem Soc 77 1608 1955]. Acridine can also be purified by crystallisation from n-heptane and then from ethanol/water after pre-treatment with activated charcoal, or by chromatography on alumina with pet ether in a darkened room. Alternatively, acridine can be precipitated as the hydrochloride from *benzene solution by adding HCl, after which the base is regenerated, dried at 110o/50mm, and recrystallised to constant melting point from pet ether [Cumper et al. J Chem Soc 4518 1962]. The regenerated free base may be recrystallised, chromatographed on basic alumina, then vacuum-sublimed and zone-refined. [Williams & Clarke, J Chem Soc, Faraday Trans 1 73 514 1977, Albert, The Acridines Arnold Press 1966.] It can exist in five crystalline forms and is steam volatile. It is a strong IRRITANT to skin and mucous membranes and can become a chronic irritant— handle it with CARE. [Beilstein 20/8 V 199.]

Inkompatibilitäten

Acridine and its derivatives are widely used in the production of dyestuffs, such as acriflavine, benzoflavine, and chrysaniline; and in the synthesis of pharmaceuticals; such as aurinacrine, proflavine, and rivanol. A constituent of coal tar, coal tar creosote; found in wastes from gas and tar plants and coke oven emissions. Incompatibilities: Strong acids, strong oxidizers.

Waste disposal

Incineration with nitrogen oxide removal from the effluent gas by scrubber, catalytic, or thermal device.

Acridin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Acridin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 141)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Zhengzhou Yuanli Biological Technology Co., Ltd
0086-371-67897895
info@zzyuanli.cn CHINA 136 58
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58
Patience Biological Engineering (Shanghai)Co.,Ltd.
13818903334
admin@pssh.com.cn CHINA 2 58
Chongqing Chemdad Co.,Ltd
+86-19923101450
sales@chemdad.com CHINA 4001 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20115 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58

260-94-6(Acridin)Verwandte Suche:


  • Acridine;Dibenzo[b,e]pyridine
  • ACRIDINE, FOR FLUORESCENCE
  • ACRIDINE 97%
  • Acridine, 98+%
  • Acridine Zone Refined (number of passes:45)
  • Acridine 1g [260-94-6]
  • Acridine Zone Refined
  • Acridine, 98% 25GR
  • Acridine, 98% 5GR
  • NSC 3408
  • ACRIDINE (D9, 98%)
  • 10-Azaanthracene
  • 2,3,5,6-dibenzopyridine
  • 2,3-Benzoquinoline
  • 9-Azaanthracene
  • Aceridine
  • Acrydine
  • Akridin
  • benzo(b)quinoline
  • Benzo[b]quinoline
  • Coal tar pitch volatiles:acridine
  • coaltarpitchvolatiles:acridine
  • DIBENZO[B,E]PYRIDINE
  • ACRIDINE
  • 260-94-6
  • 266-94-6
  • C6H4CHNC6H4
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