Everolimus manufacturers and suppliers

Everolimus suppliers

Properties

Melting point:: NA

Boiling point:: 998.7±75.0 °C(Predicted)

Density: 1.18±0.1 g/cm3(Predicted)

Flash point:: 2℃

storage temp.: -20°C

solubility: Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).

form: solid

pka: 10.40±0.70(Predicted)

color: White

Water Solubility: Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.

Stability:: Hygroscopic

InChIKey: HKVAMNSJSFKALM-GKUWKFKPSA-N

Safety Information

Symbol(GHS): GHS08,GHS09

Signal word: Warning

Hazard statements: H351-H361fd-H373-H410

Precautionary statements: P202-P260-P273-P280-P308+P313-P391

Hazard Codes: T,Xn,F

Risk Statements: 48/25-36-20/21/22-11

Safety Statements: 45-36/37-26-16

RIDADR: UN 1648 3 / PGII

WGK Germany: 2

F: 10

HS Code: 29349990

Use

Everolimus is a derivative of Rapamycin(sirolimus), and works similarly to Rapamycin as an mTOR(mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors, Everolimus takes effect solely on the mTORC1 protein and not on the mTORC2 protein[1]. In transplantation medicine, it is marketed under the trade names Zortress(USA) and Certican(Europe). It has been also used for the treatment of tumors, being marketed as Afinitor(general tumours) and Votubia(tumours as a result of TSC) in oncology.

You can find Everolimus suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.