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ChemicalBook >> CAS DataBase List >> SW203668 (trifluoroacetate salt)

SW203668 (trifluoroacetate salt)

SW203668 (trifluoroacetate salt) price.
  • $37 - $226
  • Product name: SW203668 (trifluoroacetate salt)
  • CAS: 2117405-48-6
  • MF: C24H20F3N3O4S
  • MW: 503.5
  • EINECS:
  • MDL Number:MFCD30480921
  • Synonyms:SW203668 (trifluoroacetate salt);SW203668 (trifluoroacetate salt),SW-203668 (trifluoroacetate salt);4-(aminophenylmethyl)-N-(6-methoxy-2-benzothiazolyl)-benzamide,trifluoroacetatesalt
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number4637EH
  • Product description4-[Amino(phenyl)methyl]-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide;2,2,2-trifluoroaceticacid
  • Packaging5mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19379
  • Product descriptionSW203668 (trifluoroacetate salt)
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19379
  • Product descriptionSW203668 (trifluoroacetate salt)
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19379
  • Product descriptionSW203668 (trifluoroacetate salt)
  • Packaging10mg
  • Price$213
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4637EH 4-[Amino(phenyl)methyl]-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide;2,2,2-trifluoroaceticacid 5mg $226 2021-12-16 Buy
Cayman Chemical 19379 SW203668 (trifluoroacetate salt) 1mg $37 2024-03-01 Buy
Cayman Chemical 19379 SW203668 (trifluoroacetate salt) 5mg $116 2024-03-01 Buy
Cayman Chemical 19379 SW203668 (trifluoroacetate salt) 10mg $213 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 20 mg/mL; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

SW203668 is an irreversible inhibitor of stearoyl-CoA desaturase (IC50 = 54 nM). It is selectively cytotoxic to H2122, H460, HCC44, and HCC95 cell lines that express cytochrome P450 (CYP) isoform CYP4F11 over eight other cancer cell lines that lack CYP4F11 in vitro (IC50s = 22-116 and >10,000 nM, respectively) and ectopic expression of CYP4F11 in SW203668-insensitive H1155 cells results in sensitization to SW203668. In vivo, SW203668 reduces tumor growth rate without reducing sebocyte production in the H2122 wild-type and nonobese diabetic severe combined immunodeficiency (NOD-SCID) mouse xenograft models when administered at doses of 20 and 6 mg/kg, respectively.