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ChemicalBook >> CAS DataBase List >> 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7

7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7

7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 price.
  • $495 - $1190
  • Product name: 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7
  • CAS: 349553-94-2
  • MF: C26H37D7O2
  • MW: 395.67
  • EINECS:
  • MDL Number:MFCD01317395
  • Synonyms:7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7;cholest-5-en-3,7α-diol-d7;CHOLEST-5-EN-3,7Α-DIOL-D7;7Α-HYDROXYCHOLESTEROL-D7;7alpha-hydroxycholesterol-d7;7α-hydroxy Cholesterol-d7;7α-Hydroxycholesterol-25?26?26?26?27?27?27-[d7];Cholesterol Impurity 37;cholest-5-en-3?,7α-diol-d7
4 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBAR0001509
  • Product description7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 95.00%
  • Packaging5MG
  • Price$500.23
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25547
  • Product description7α-hydroxy Cholesterol-d7 ≥99% deuterated forms (d1-d7)
  • Packaging1mg
  • Price$638
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product numberD642
  • Product description7α-Hydroxycholesterol-25,26,26,26,27,27,27-d7 97%
  • Packaging5mg
  • Price$1190
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberH917962
  • Product description7α-Hydroxycholesterol-d7
  • Packaging1mg
  • Price$495
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation BAR0001509 7ALPHA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 95.00% 5MG $500.23 2021-12-16 Buy
Cayman Chemical 25547 7α-hydroxy Cholesterol-d7 ≥99% deuterated forms (d1-d7) 1mg $638 2024-03-01 Buy
Medical Isotopes, Inc. D642 7α-Hydroxycholesterol-25,26,26,26,27,27,27-d7 97% 5mg $1190 2021-12-16 Buy
TRC H917962 7α-Hydroxycholesterol-d7 1mg $495 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :DMF: 2 mg/ml; DMSO: 0.1 mg/ml; Ethanol: 20 mg/ml
form :A solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS. 7α-hydroxy Cholesterol is an oxysterol and a precursor in the biosynthesis of the bile acids cholic acid (CA; ) and chenodeoxycholic acid (CDCA; ). It is formed via the oxidation of cholesterol by cholesterol 7α-hydroxylase/CYP7A1 in rat liver microsomes. 7α-hydroxy Cholesterol (40 μM) increases levels of the adhesion molecules ICAM-1, VCAM-1, and E-selectin in human umbilical vein endothelial cells (HUVECs). It increases secretion of chemokine (C-C motif) ligand 2 (CCL2) and matrix metalloproteinase-9 (MMP-9) in serum-deprived THP-1 cells when used at a concentration of 5 μg/ml. 7α-hydroxy Cholesterol has been found in macrophages isolated from atherosclerotic lesions in rabbits fed a high-cholesterol diet.

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