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ChemicalBook >> CAS DataBase List >> Glucagon Receptor Antagonist I

Glucagon Receptor Antagonist I

Glucagon Receptor Antagonist I price.
  • $74 - $583
  • Product name: Glucagon Receptor Antagonist I
  • CAS: 438618-32-7
  • MF: C20H30N2OS
  • MW: 346.53
  • EINECS:
  • MDL Number:MFCD01920208
  • Synonyms:Glucagon Receptor Antagonist I;N-[3-cyano-6-(2-methylbutan-2-yl)-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-ethylbutanamide;Butanamide, N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-2-ethyl-;hGCGR Antagonist
5 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number8227CC
  • Product descriptionGlucagonReceptorAntagonistI
  • Packaging1mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8227CC
  • Product descriptionGlucagonReceptorAntagonistI
  • Packaging5mg
  • Price$583
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21223
  • Product descriptionGlucagon Receptor Antagonist I ≥99%
  • Packaging500μg
  • Price$74
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21223
  • Product descriptionGlucagon Receptor Antagonist I ≥99%
  • Packaging1mg
  • Price$132
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21223
  • Product descriptionGlucagon Receptor Antagonist I ≥99%
  • Packaging5mg
  • Price$476
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8227CC GlucagonReceptorAntagonistI 1mg $233 2021-12-16 Buy
AK Scientific 8227CC GlucagonReceptorAntagonistI 5mg $583 2021-12-16 Buy
Cayman Chemical 21223 Glucagon Receptor Antagonist I ≥99% 500μg $74 2024-03-01 Buy
Cayman Chemical 21223 Glucagon Receptor Antagonist I ≥99% 1mg $132 2024-03-01 Buy
Cayman Chemical 21223 Glucagon Receptor Antagonist I ≥99% 5mg $476 2024-03-01 Buy

Properties

Boiling point :517.8±50.0 °C(Predicted)
Density :1.07±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :White crystalline solid.
pka :13.46±0.40(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Glucagon Receptor Antagonist I is a potent and selective cell-permeable thienyl-amide compound that acts as a competitive antagonist of the glucagon receptor. Exhibits binding to hGCGR with high affinity and prevents its interaction with glucagon (IC50 = 181 nM, KDB = 81 nM, and pA2 = 7.1 in membranes prepared from CHO-hGCGR). Also suppresses glucagon-induced glycogenolysis in human primary hepatocytes and in mice (50 mg/kg, ip).

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