3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione
![3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione price.](/CAS/GIF/905854-02-6.gif)
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- $28 - $8042
- Product name: 3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione
- CAS: 905854-02-6
- MF: C23H19N3O2
- MW: 369.42
- EINECS:
- MDL Number:MFCD11977597
- Synonyms:3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione Tivantinib;3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione;Tivantinib;(-)-3(R),4(R)-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione, (-)-trans-3-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dione;TIVANTINIB ARQ-197;(3R,4R)-3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-2,5-pyrrolidinedione;Tivantinib/ARQ197/ARQ-197;(3R,4R)-3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)pyrrolidine-2,5-dio
32 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 1unit
- 5mg
- 10mg
- 20mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5688
- Product descriptionTivantinib
- Packaging50mg
- Price$617
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5688
- Product descriptionTivantinib
- Packaging100mg
- Price$1053
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0311
- Product descriptionTivantinib
- Packaging1g
- Price$8042
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA891951
- Product descriptionTivantinib 98+%
- Packaging5mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA891951
- Product descriptionTivantinib 98+%
- Packaging10mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8325
- Product descriptionTivantinib(ARQ197)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8325
- Product descriptionTivantinib(ARQ197)
- Packaging20mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8325
- Product descriptionTivantinib(ARQ197)
- Packaging100mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60395
- Product descriptionTivantinib(ARQ197) ≥98%
- Packaging10mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180926
- Product descriptionTivantinib (ARQ 197) >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180926
- Product descriptionTivantinib (ARQ 197) >98%
- Packaging250mg
- Price$986
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT44530
- Product descriptionTivantinib
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFT44530
- Product descriptionTivantinib
- Packaging50mg
- Price$437.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17135
- Product descriptionTivantinib ≥98%
- Packaging1mg
- Price$36
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17135
- Product descriptionTivantinib ≥98%
- Packaging5mg
- Price$78
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17135
- Product descriptionTivantinib ≥98%
- Packaging10mg
- Price$120
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5688 | Tivantinib | 50mg | $617 | 2021-12-16 | Buy |
| AK Scientific | SYN5688 | Tivantinib | 100mg | $1053 | 2021-12-16 | Buy |
| AK Scientific | Y0311 | Tivantinib | 1g | $8042 | 2021-12-16 | Buy |
| Ambeed | A891951 | Tivantinib 98+% | 5mg | $45 | 2021-12-16 | Buy |
| Ambeed | A891951 | Tivantinib 98+% | 10mg | $67 | 2021-12-16 | Buy |
| ApexBio Technology | A8325 | Tivantinib(ARQ197) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8325 | Tivantinib(ARQ197) | 20mg | $120 | 2021-12-16 | Buy |
| ApexBio Technology | A8325 | Tivantinib(ARQ197) | 100mg | $380 | 2021-12-16 | Buy |
| Arctom | CFN60395 | Tivantinib(ARQ197) ≥98% | 10mg | $208 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180926 | Tivantinib (ARQ 197) >98% | 100mg | $542.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180926 | Tivantinib (ARQ 197) >98% | 250mg | $986 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FT44530 | Tivantinib | 10mg | $125 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FT44530 | Tivantinib | 50mg | $437.5 | 2021-12-16 | Buy |
| Cayman Chemical | 17135 | Tivantinib ≥98% | 1mg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 17135 | Tivantinib ≥98% | 5mg | $78 | 2024-03-01 | Buy |
| Cayman Chemical | 17135 | Tivantinib ≥98% | 10mg | $120 | 2024-03-01 | Buy |
Properties
Boiling point :715.9±60.0 °C(Predicted)
Density :1.49
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :9.28±0.70(Predicted)
form :Solid
color :Light Orange
Density :1.49
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :9.28±0.70(Predicted)
form :Solid
color :Light Orange
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
MET is a proto-oncogene that encodes the hepatocyte growth factor receptor c-Met. The receptor has normal roles in morphogenesis, migration, apoptosis, and angiogenesis. Dysregulation of c-Met occurs in many types of cancer. Tivantinib is a staurosporine derivative that binds to dephosphorylated c-Met kinase, yet its mechanism of action is not known. Tivantinib has been tested in clinical studies for its ability to selectively inhibit c-Met. However, it can promote mitotic arrest and apoptosis of various human tumor cell lines (EC50s ranging from 60-600 nM) through mechanisms independent of its ability to bind c-Met. Tivantinib has been reported to bind directly to the colchicine binding site of tubulin, reducing tubulin polymerization in cells and in mouse xenograft tumors in vivo.More related product prices
Tivozanib (hydrate) N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea Afatinib (BIBW 2992) BI 2536 Dasatinib 477575-56-7 Cabozantinib 405169-16-6 ARRY-334543 Momelotinib CO-1686 PLX3397 (Pexidartinib) CAL-101 Lestaurtinib Masitinib (AB1010) Decernotinib OlaparibRelated product price
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$50-2541.5 - Afatinib (BIBW 2992)
$24-2658.8
Suppliers and manufacturers
Hebei Duling International Trade Co. LTD
![3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione Tivantinib](/ProductImageEN/2023-04/small/6660a4c6-eb46-459d-b089-364a65051220.png)
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei Jusheng Technology Co.,Ltd.
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED
Career Henan Chemica Co
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
$50.00 /1KG
3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione Tivantinib CAS:905854-02-6
3-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-4-(1H-indol-3-yl)-pyrrolidine-2,5-dione Tivantinib CAS:905854-02-6