Akt Inhibitor X
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- $57 - $1285
- Product name: Akt Inhibitor X
- CAS: 925681-41-0
- MF: C20H26Cl2N2O
- MW: 381.34
- EINECS:-0
- MDL Number:
- Synonyms:Akt Inhibitor X;10-DEBC HCl;2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine hydrochloride (1:1);N-diethyl-10H-phenoxazine-10-butanamine;10-NCP;10-NCP (10-DEBC;SVKSJUIYYCQZEC-UHFFFAOYSA-N
21 prices
Selected condition：
Brand
- aablocks
- ApexBio Technology
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- Manufactureraablocks
- Product numberAA01E5RO
- Product description4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride ≥95%
- Packaging1mg
- Price$57
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5RO
- Product description4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride ≥95%
- Packaging5mg
- Price$154
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01E5RO
- Product description4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride ≥95%
- Packaging10mg
- Price$197
- Updated2026-05-30
- Buy
- ManufacturerApexBio Technology
- Product numberB7105
- Product description10-DEBC hydrochloride
- Packaging10mg
- Price$357
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7105
- Product description10-DEBC hydrochloride
- Packaging50mg
- Price$965
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberFD29857
- Product description10-DEBC hydrochloride
- Packaging25mg
- Price$892.5
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFD29857
- Product description10-DEBC hydrochloride
- Packaging50mg
- Price$1285
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFD29857
- Product description10-DEBC hydrochloride
- Packaging10mg
- Price$428.3
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFD29857
- Product description10-DEBC hydrochloride
- Packaging5mg
- Price$285.55
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number14863
- Product descriptionAkt Inhibitor X ≥95%
- Packaging50mg
- Price$583
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number14863
- Product descriptionAkt Inhibitor X ≥95%
- Packaging5mg
- Price$154
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14863
- Product descriptionAkt Inhibitor X ≥95%
- Packaging1mg
- Price$57
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14863
- Product descriptionAkt Inhibitor X ≥95%
- Packaging10mg
- Price$197
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0019892
- Product description10-DEBC hydrochloride 99.82%
- Packaging10mg
- Price$347
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0019892
- Product description10-DEBC hydrochloride 99.82%
- Packaging5mg
- Price$217
- Updated2026-06-04
- Buy
- ManufacturerSigma-Aldrich
- Product number124020
- Product descriptionAkt Inhibitor X - CAS 925681-41-0 - Calbiochem
- Packaging5mg
- Price$444
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01E5RO | 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride ≥95% | 1mg | $57 | 2026-05-30 | Buy |
| aablocks | AA01E5RO | 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride ≥95% | 5mg | $154 | 2026-05-30 | Buy |
| aablocks | AA01E5RO | 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride ≥95% | 10mg | $197 | 2026-05-30 | Buy |
| ApexBio Technology | B7105 | 10-DEBC hydrochloride | 10mg | $357 | 2026-05-06 | Buy |
| ApexBio Technology | B7105 | 10-DEBC hydrochloride | 50mg | $965 | 2026-05-06 | Buy |
| Biosynth | FD29857 | 10-DEBC hydrochloride | 25mg | $892.5 | 2026-06-04 | Buy |
| Biosynth | FD29857 | 10-DEBC hydrochloride | 50mg | $1285 | 2026-06-04 | Buy |
| Biosynth | FD29857 | 10-DEBC hydrochloride | 10mg | $428.3 | 2026-06-04 | Buy |
| Biosynth | FD29857 | 10-DEBC hydrochloride | 5mg | $285.55 | 2026-06-04 | Buy |
| Cayman Chemical | 14863 | Akt Inhibitor X ≥95% | 50mg | $583 | 2023-06-20 | Buy |
| Cayman Chemical | 14863 | Akt Inhibitor X ≥95% | 5mg | $154 | 2026-04-30 | Buy |
| Cayman Chemical | 14863 | Akt Inhibitor X ≥95% | 1mg | $57 | 2026-04-30 | Buy |
| Cayman Chemical | 14863 | Akt Inhibitor X ≥95% | 10mg | $197 | 2026-04-30 | Buy |
| ChemScene | CS-0019892 | 10-DEBC hydrochloride 99.82% | 10mg | $347 | 2026-06-04 | Buy |
| ChemScene | CS-0019892 | 10-DEBC hydrochloride 99.82% | 5mg | $217 | 2026-06-04 | Buy |
| Sigma-Aldrich | 124020 | Akt Inhibitor X - CAS 925681-41-0 - Calbiochem | 5mg | $444 | 2026-04-30 | Buy |
Properties
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :Powder
color :White to off-white
Water Solubility :Soluble to 100mM in water or DMSO
Sensitive :Light Sensitive & Hygroscopic
InChI :1S/C20H25ClN2O.ClH/c1-3-22(4-2)13-7-8-14-23-17-9-5-6-10-19(17)24-20-12-11-16(21)15-18(20)23;/h5-6,9-12,15H,3-4,7-8,13-14H2,1-2H3;1H
InChIKey :SVKSJUIYYCQZEC-UHFFFAOYSA-N
SMILES :ClC(C=C1)=CC2=C1OC3=C(N2CCCCN(CC)CC)C=CC=C3
solubility :Soluble in DMSO
form :Powder
color :White to off-white
Water Solubility :Soluble to 100mM in water or DMSO
Sensitive :Light Sensitive & Hygroscopic
InChI :1S/C20H25ClN2O.ClH/c1-3-22(4-2)13-7-8-14-23-17-9-5-6-10-19(17)24-20-12-11-16(21)15-18(20)23;/h5-6,9-12,15H,3-4,7-8,13-14H2,1-2H3;1H
InChIKey :SVKSJUIYYCQZEC-UHFFFAOYSA-N
SMILES :ClC(C=C1)=CC2=C1OC3=C(N2CCCCN(CC)CC)C=CC=C3
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Akt functions as a key component in multiple signaling pathways to promote cell survival by mediating resistance to apoptosis. Akt inhibitor X is a cell permeable phenoxazine derivative that suppresses insulin-like growth factor 1 (IGF-1)-stimulated phosphorylation of Akt with an IC50 value of 1-2 μM. This compound has been shown to block IGF-1-stimulated nuclear translocation of Akt in Rh1 cells and to inhibit the growth of Rh1, Rh18, and Rh30 cells with IC50 values of 2-5 μM. Inhibition of Akt phosphorylation by 5 μM of this compound strongly correlates to the inhibition of the downstream targets, mTOR, p70S6 kinase, and S6 ribosomal protein and to an increase in apoptosis.Related product price
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