Alectinib
|
- $8 - $1872
- Product name: Alectinib
- CAS: 1256580-46-7
- MF: C30H34N4O2
- MW: 482.62
- EINECS:821-541-6
- MDL Number:MFCD19440988
- Synonyms:AF-802;CH-5424802/RG-7853;Alectinib;AF-802,RG-7853;9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile Alectinib (CH5424802);CH5424802-alectinib;9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile CH5424802;CH5424802, Alectinib, AF802
67 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 1mg
- 20mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 0.25g
- 250mg
- 250.00mg
- 500mg
- 0.5g
- 1.00g
- 1000mg
- 1g
- 2g
- 5.00g
- 5g
- 10g
- 25g
- Manufactureraablocks
- Product numberAA000O6P
- Product description9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98%
- Packaging5mg
- Price$8
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000O6P
- Product description9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98%
- Packaging10mg
- Price$10
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000O6P
- Product description9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98%
- Packaging100mg
- Price$21
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000O6P
- Product description9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98%
- Packaging250mg
- Price$35
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000O6P
- Product description9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98%
- Packaging1g
- Price$109
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000O6P
- Product description9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98%
- Packaging5g
- Price$407
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000O6P
- Product description9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98%
- Packaging10g
- Price$674
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000O6P
- Product description9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98%
- Packaging25g
- Price$1342
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberI-9209
- Product descriptionAlectinib 98%
- Packaging25G
- Price$1100
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberI-9209
- Product descriptionAlectinib 98%
- Packaging5G
- Price$330
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberI-9209
- Product descriptionAlectinib 98%
- Packaging1G
- Price$100
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0295
- Product descriptionCH5424802
- Packaging100mg
- Price$211
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8393
- Product descriptionCH5424802
- Packaging50mg
- Price$145
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8393
- Product descriptionCH5424802
- Packaging5mg
- Price$69
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBISN0151
- Product descriptionAlectinib 98%
- Packaging250mg
- Price$55
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBISN0151
- Product descriptionAlectinib 98%
- Packaging100mg
- Price$33
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000O6P | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98% | 5mg | $8 | 2026-05-25 | Buy |
| aablocks | AA000O6P | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98% | 10mg | $10 | 2026-05-25 | Buy |
| aablocks | AA000O6P | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98% | 100mg | $21 | 2026-05-25 | Buy |
| aablocks | AA000O6P | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98% | 250mg | $35 | 2026-05-25 | Buy |
| aablocks | AA000O6P | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98% | 1g | $109 | 2026-05-25 | Buy |
| aablocks | AA000O6P | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98% | 5g | $407 | 2026-05-25 | Buy |
| aablocks | AA000O6P | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98% | 10g | $674 | 2026-05-25 | Buy |
| aablocks | AA000O6P | 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile 98% | 25g | $1342 | 2026-05-25 | Buy |
| ACHEMBLOCK | I-9209 | Alectinib 98% | 25G | $1100 | 2026-05-27 | Buy |
| ACHEMBLOCK | I-9209 | Alectinib 98% | 5G | $330 | 2026-05-27 | Buy |
| ACHEMBLOCK | I-9209 | Alectinib 98% | 1G | $100 | 2026-05-27 | Buy |
| AK Scientific | Y0295 | CH5424802 | 100mg | $211 | 2021-12-16 | Buy |
| ApexBio Technology | A8393 | CH5424802 | 50mg | $145 | 2026-05-06 | Buy |
| ApexBio Technology | A8393 | CH5424802 | 5mg | $69 | 2026-05-06 | Buy |
| Apolloscientific | BISN0151 | Alectinib 98% | 250mg | $55 | 2026-06-04 | Buy |
| Apolloscientific | BISN0151 | Alectinib 98% | 100mg | $33 | 2026-06-04 | Buy |
Properties
Melting point :274-276°C
Boiling point :722.5±60.0 °C(Predicted)
Density :1.28
storage temp. :-20°
solubility :Soluble in DMSO (up to 5 mg/ml with warming).
form :solid
pka :13.70±0.40(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.
InChIKey :KDGFLJKFZUIJMX-UHFFFAOYSA-N
SMILES :N1C2=C(C=CC(C#N)=C2)C2=C1C(C)(C)C1=CC(N3CCC(N4CCOCC4)CC3)=C(CC)C=C1C2=O
Boiling point :722.5±60.0 °C(Predicted)
Density :1.28
storage temp. :-20°
solubility :Soluble in DMSO (up to 5 mg/ml with warming).
form :solid
pka :13.70±0.40(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.
InChIKey :KDGFLJKFZUIJMX-UHFFFAOYSA-N
SMILES :N1C2=C(C=CC(C#N)=C2)C2=C1C(C)(C)C1=CC(N3CCC(N4CCOCC4)CC3)=C(CC)C=C1C2=O
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that promotes cell proliferation and blocks apoptosis. CH5424802 is an ATP-competitive inhibitor of ALK (IC50 = 1.9 nM) that also inhibits F1174L, R1275Q, and L1196M mutants of ALK (IC50s = 1.0, 3.5, and 1.6 nM, respectively). It shows more than 500-fold selectivity for ALK over a panel of 24 other kinases. CH5424802 is orally available and inhibits the growth of tumors in mouse xenograft models of nonsmall cell lung cancer and anaplastic large-cell lymphoma.More related product prices
AZD-9291 Crizotinib Ibrutinib AP26113 Erlotinib hydrochloride Ceritinib (LDK378) 53617-35-9 Neratinib 918505-84-7 Nintedanib EAI-045 918504-65-1Related product price
-
AZD-9291
$4-1800 -
Crizotinib
$5-1963.5 -
Ibrutinib
$5-1360
Suppliers and manufacturers
Cangzhou Huiying Pharmaceutical Technology Co. , Ltd.
Shanghai Famo Bio-chemical Technology Company Ltd.
Hubei Hicks Biochemical Co., Ltd
NANJING ZENJI PHARMACEUTICALS
Nanjing Becas pharmatech Ltd.
Jiangsu Baiaoxinkang Pharmaceutical Technology Co. , Ltd.
Jiangsu Purun Biomedical Co., Ltd.
Shanghai Boyle Chemical Co., Ltd.
J & K SCIENTIFIC LTD.
Chembest Research Laboratories Limited