BISINDOLYLMALEIMIDE III
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- $57 - $425
- Product name: BISINDOLYLMALEIMIDE III
- CAS: 137592-43-9
- MF: C23H20N4O2
- MW: 384.43
- EINECS:
- MDL Number:MFCD01076633
- Synonyms:BISINDOLYLMALEIMIDE III;3-[1-(3-aminopropyl)indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-;3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione;Bisindolylmaleimide III, PKC inhibitor;Bisindolylmaleimide III, 10 mM in DMSO
6 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Cayman Chemical
- Usbiological
Package
- 1mg
- 5mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0112-M005
- Product descriptionBisindolylmaleimideIII ≥98%(NMR)
- Packaging5mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0282CA
- Product description3-[1-(3-Aminopropyl)-1H-indol-3-YL]-4-(1H-indol-3-YL)-1H-pyrrole-2,5-dione
- Packaging5mg
- Price$289
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11072
- Product descriptionBisindolylmaleimide III ≥98%
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11072
- Product descriptionBisindolylmaleimide III ≥98%
- Packaging5mg
- Price$172
- Updated2024-03-01
- Buy
- ManufacturerUsbiological
- Product number044604
- Product descriptionBisindolylmaleimide III
- Packaging1mg
- Price$295
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number162899
- Product descriptionBisindolylmaleimide III
- Packaging5mg
- Price$425
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-0112-M005 | BisindolylmaleimideIII ≥98%(NMR) | 5mg | $165 | 2021-12-16 | Buy |
| AK Scientific | 0282CA | 3-[1-(3-Aminopropyl)-1H-indol-3-YL]-4-(1H-indol-3-YL)-1H-pyrrole-2,5-dione | 5mg | $289 | 2021-12-16 | Buy |
| Cayman Chemical | 11072 | Bisindolylmaleimide III ≥98% | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 11072 | Bisindolylmaleimide III ≥98% | 5mg | $172 | 2024-03-01 | Buy |
| Usbiological | 044604 | Bisindolylmaleimide III | 1mg | $295 | 2021-12-16 | Buy |
| Usbiological | 162899 | Bisindolylmaleimide III | 5mg | $425 | 2021-12-16 | Buy |
Properties
Boiling point :708.7±60.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
solubility :DMSO: soluble; Methanol: soluble
form :A crystalline solid
pka :8.15±0.60(Predicted)
color :Brown to reddish brown
Density :1.41±0.1 g/cm3(Predicted)
solubility :DMSO: soluble; Methanol: soluble
form :A crystalline solid
pka :8.15±0.60(Predicted)
color :Brown to reddish brown
Safety Information
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Description
Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 μM, bisindolylmaleimide III inhibits 93% of PKCα kinase activity and also inhibits many other protein kinases including, S6K1, MAPKAP-K1, RSK2 and MSK1 with similar potency. Additionally, it inhibits PDK1, an important kinase in the insulin signaling pathway, with an IC50 value of 3.8 μM.More related product prices
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