Welcome to chemicalbook!
China English Japan Germany
010-86108875
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structure Search
RFQ
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook Sign in

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> Cabozantinib

Cabozantinib

Cabozantinib price.
  • $7 - $2167
  • Product name: Cabozantinib
  • CAS: 849217-68-1
  • MF: C28H24FN3O5
  • MW: 501.51
  • EINECS:692-846-8
  • MDL Number:MFCD20926324
  • Synonyms:Cabozantinib(XL184Malate);Cabozantinib (XL184, BMS-907351);XL-186;1,1-cyclopropanedicarboxamide, n'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n-(4-fluorophenyl)-;N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide Cabozantinib (XL184, BMS-907351);Cabozantinib, >=98%;1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide Cabozantinib
Price74 Properties Safety Information Description
74 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Tocris
  • TRC
  • Usbiological
Package
  • 20mg
  • 25mg
  • 500mg
  • 10mM(in1mLDMSO)
  • 1.00g
  • 50
  • 10
  • 10mM*1mLinDMSO
  • 1000mg
  • 2000mg
  • EvaluationSample
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 200MG
  • 250mg
  • 1g
  • 5g
  • 10g
  • Manufactureraablocks
  • Product numberAA003A5Y
  • Product descriptionN'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98%
  • Packaging1mg
  • Price$8
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A5Y
  • Product descriptionN'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98%
  • Packaging100mg
  • Price$18
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A5Y
  • Product descriptionN'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98%
  • Packaging250mg
  • Price$27
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A5Y
  • Product descriptionN'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98%
  • Packaging1g
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003A5Y
  • Product descriptionN'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98%
  • Packaging5g
  • Price$166
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-6215
  • Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 97%
  • Packaging5G
  • Price$135
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberG-6215
  • Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 97%
  • Packaging1G
  • Price$50
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0755-M010
  • Product descriptionCabozantinib ≥98%(HPLC)
  • Packaging10mg
  • Price$145
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0755-M050
  • Product descriptionCabozantinib ≥98%(HPLC)
  • Packaging50mg
  • Price$460
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1138-M050
  • Product descriptionCabozantinib ≥95%
  • Packaging50mg
  • Price$497
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1138
  • Product descriptionCabozantinib
  • Packaging100mg
  • Price$845
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1138
  • Product descriptionCabozantinib
  • Packaging10mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA200488
  • Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 98+%
  • Packaging250mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA200488
  • Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 98+%
  • Packaging50mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA200488
  • Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 98+%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA200488
  • Product descriptionN-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 98+%
  • Packaging10mg
  • Price$7
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003A5Y N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98% 1mg $8 2026-05-28 Buy
aablocks AA003A5Y N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98% 100mg $18 2026-05-28 Buy
aablocks AA003A5Y N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98% 250mg $27 2026-05-28 Buy
aablocks AA003A5Y N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98% 1g $52 2026-05-28 Buy
aablocks AA003A5Y N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide 98% 5g $166 2026-05-28 Buy
ACHEMBLOCK G-6215 N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 97% 5G $135 2026-05-27 Buy
ACHEMBLOCK G-6215 N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 97% 1G $50 2026-05-27 Buy
Adipogen Life Sciences CDX-C0755-M010 Cabozantinib ≥98%(HPLC) 10mg $145 2026-05-06 Buy
Adipogen Life Sciences CDX-C0755-M050 Cabozantinib ≥98%(HPLC) 50mg $460 2026-05-06 Buy
Adipogen Life Sciences SYN-1138-M050 Cabozantinib ≥95% 50mg $497 2021-12-16 Buy
AK Scientific SYN1138 Cabozantinib 100mg $845 2021-12-16 Buy
AK Scientific SYN1138 Cabozantinib 10mg $190 2021-12-16 Buy
Ambeed A200488 N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 98+% 250mg $65 2021-12-16 Buy
Ambeed A200488 N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 98+% 50mg $12 2021-12-16 Buy
Ambeed A200488 N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 98+% 100mg $15 2021-12-16 Buy
Ambeed A200488 N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 98+% 10mg $7 2021-12-16 Buy
Next Last

Properties

Melting point :212-215°C
Boiling point :758.1±60.0 °C(Predicted)
Density :1.396
storage temp. :-20°C
solubility :Soluble in DMSO
form :White powder.
pka :13.86±0.70(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :ONIQOQHATWINJY-UHFFFAOYSA-N
SMILES :C1(C(NC2=CC=C(OC3C4C(N=CC=3)=CC(OC)=C(OC)C=4)C=C2)=O)(C(NC2=CC=C(F)C=C2)=O)CC1

Safety Information

Symbol(GHS): Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

XL184 is a pan tyrosine kinase inhibitor that primarily targets VEGFR2 (IC50 = 0.035 nM) and c-Met (IC50 = 1.3 nM) but also inhibits RET, c-Kit, Axl, FLT3, and Tie2 (IC50s = 5.2, 4.6, 7, 11.3, and 14.3 nM, respectively). In in vivo breast, lung, and glioma tumor models that represent dysregulated c-Met and VEGFR signaling, XL184 was shown to reduce tumor and endothelial cell proliferation, inhibiting both angiogenesis and metastasis. XL184 has undergone clinical trial in a broad number of cancers, including thyroid carcinoma, prostate cancer, ovarian cancer, melanoma, breast cancer, non-small cell lung cancer, hepatocellular cancer, renal cell carcinoma, and glioblastoma.

More related product prices

Foretinib (GSK1363089) Crizotinib Sunitinib Malate 871700-17-3 Lenvatinib Dacomitinib (PF299804) OTAVA-BB 1115529 Axitinib Afatinib (BIBW 2992) AP26113 1195765-45-7 WZ4002 XL147 XL019 GZD 824 918504-65-1 Vandetanib BMS 833923 pilaralisib XL413 (BMS-863233)

Related product price

Suppliers and manufacturers

Changzhou Borl Biotechnology Co.,LTD Jinan Chuanbei Biotechnology Co., Ltd Hangzhou Runyan Medical Technology Co., LTD Zhengzhou Science Pharmaceutical Technology Co., Ltd Tianjin Famoxi Biopharmaceutical Technology Co., Ltd Shanghai Boyle Chemical Co., Ltd. ChemFuture PharmaTech (Jiangsu) Ltd Chembest Research Laboratories Limited Beijing HwrkChemical Technology Co., Ltd JinYan Chemicals(ShangHai) Co.,Ltd.