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ChemicalBook >> CAS DataBase List >> CeMMEC1

CeMMEC1

CeMMEC1 price.
  • $32 - $1500
  • Product name: CeMMEC1
  • CAS: 440662-09-9
  • MF: C19H16N2O4
  • MW: 336.34
  • EINECS:-0
  • MDL Number:MFCD02939849
  • Synonyms:CeMMEC1;4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-;CeMMEC1(free base);cemmecl;Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1
15 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1480DB
  • Product descriptionCeMMEC1
  • Packaging10mg
  • Price$572
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19956
  • Product descriptionCeMMEC1 ≥98%
  • Packaging500μg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19956
  • Product descriptionCeMMEC1 ≥98%
  • Packaging1mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19956
  • Product descriptionCeMMEC1 ≥98%
  • Packaging5mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19956
  • Product descriptionCeMMEC1 ≥98%
  • Packaging10mg
  • Price$426
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0040872
  • Product descriptionCeMMEC1 99.69%
  • Packaging5mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0040872
  • Product descriptionCeMMEC1 99.69%
  • Packaging10mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0040872
  • Product descriptionCeMMEC1 99.69%
  • Packaging25mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0040872
  • Product descriptionCeMMEC1 99.69%
  • Packaging50mg
  • Price$630
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0040872
  • Product descriptionCeMMEC1 99.69%
  • Packaging100mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9923
  • Product descriptionCeMMEC1 >98%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9923
  • Product descriptionCeMMEC1 >98%
  • Packaging250mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9923
  • Product descriptionCeMMEC1 >98%
  • Packaging1g
  • Price$1500
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC256565
  • Product descriptionCeMMEC1
  • Packaging5mg
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC256565
  • Product descriptionCeMMEC1
  • Packaging10mg
  • Price$525
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1480DB CeMMEC1 10mg $572 2021-12-16 Buy
Cayman Chemical 19956 CeMMEC1 ≥98% 500μg $32 2024-03-01 Buy
Cayman Chemical 19956 CeMMEC1 ≥98% 1mg $61 2024-03-01 Buy
Cayman Chemical 19956 CeMMEC1 ≥98% 5mg $243 2024-03-01 Buy
Cayman Chemical 19956 CeMMEC1 ≥98% 10mg $426 2024-03-01 Buy
ChemScene CS-0040872 CeMMEC1 99.69% 5mg $110 2021-12-16 Buy
ChemScene CS-0040872 CeMMEC1 99.69% 10mg $170 2021-12-16 Buy
ChemScene CS-0040872 CeMMEC1 99.69% 25mg $360 2021-12-16 Buy
ChemScene CS-0040872 CeMMEC1 99.69% 50mg $630 2021-12-16 Buy
ChemScene CS-0040872 CeMMEC1 99.69% 100mg $1100 2021-12-16 Buy
DC Chemicals DC9923 CeMMEC1 >98% 100mg $450 2021-12-16 Buy
DC Chemicals DC9923 CeMMEC1 >98% 250mg $800 2021-12-16 Buy
DC Chemicals DC9923 CeMMEC1 >98% 1g $1500 2021-12-16 Buy
TRC C256565 CeMMEC1 5mg $310 2021-12-16 Buy
TRC C256565 CeMMEC1 10mg $525 2021-12-16 Buy

Properties

Boiling point :590.1±50.0 °C(Predicted)
Density :1.386±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :11.38±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. This compound synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.