CeMMEC1
- CAS No.
- 440662-09-9
- Chemical Name:
- CeMMEC1
- Synonyms
- CeMMEC1;cemmecl;CeMMEC1(free base);CeMMEC1 (CeMMEC 1);CeMMEC1, 10 mM in DMSO;Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide;4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-;N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
- CBNumber:
- CB83171705
- Molecular Formula:
- C19H16N2O4
- Molecular Weight:
- 336.34
- MDL Number:
- MFCD02939849
- MOL File:
- 440662-09-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
CeMMEC1 price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19956 | CeMMEC1 ≥98% | 440662-09-9 | 500μg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 19956 | CeMMEC1 ≥98% | 440662-09-9 | 1mg | $68 | 2026-04-30 | Buy |
| Cayman Chemical | 19956 | CeMMEC1 ≥98% | 440662-09-9 | 5mg | $268 | 2026-04-30 | Buy |
| Cayman Chemical | 19956 | CeMMEC1 ≥98% | 440662-09-9 | 10mg | $469 | 2026-04-30 | Buy |
| ChemScene | CS-0040872 | CeMMEC1 98.94% | 440662-09-9 | 5mg | $65 | 2026-06-04 | Buy |
CeMMEC1 Chemical Properties, Uses, Production
Description
CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. This compound synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
Uses
CeMMEC1, shows high affinity for TAF1, and is an inhibitor of BRD4.
storage
Store at -20°C
References
[1] SARA SDELCI. Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk[J]. Nature chemical biology, 2016, 12 7: 504-510. DOI: 10.1038/nchembio.2080
CeMMEC1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4865 | 55 | |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 18916372613 | yanzihan@shyuanye.com | China | 87240 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2961 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9779 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Latest Price from CeMMEC1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-20 | CeMMEC1
440662-09-9
|
$30.00-116.00 | 98.90% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-01 | CeMMEC1
440662-09-9
|
1KG | 98% | 20Tons | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2020-01-10 | CeMMEC1
440662-09-9
|
1KG | 98%; 99% | 500g;1kg； 25kg | Career Henan Chemical Co |
