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ChemicalBook >> CAS DataBase List >> EHT1864

EHT1864

EHT1864 price.
  • $23 - $1900
  • Product name: EHT1864
  • CAS: 754240-09-0
  • MF: C25H27F3N2O4S2HCl
  • MW: 0
  • EINECS:
  • MDL Number:MFCD11114384
  • Synonyms:5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride;EHT 1864;2-(4-morpholinylmethyl)-5-[[5-[[7-(trifluoromethyl)-4-quinolinyl]thio]pentyl]oxy]-4H-pyran-4-one,hydrochloride (1:2);EHT 1864, >=98%;2-(morpholin-4-ylmethyl)-5-[5-[7-(trifluoromethyl)quinolin-4-yl]sulfanylpentoxy]pyran-4-one,dihydrochloride;CS-1239;CS-1343;EHT-1864;EHT-1864
Price67 Properties Safety Information Description
67 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM(in1mLDMSO)
  • 1g
  • 10
  • 50
  • 10mM*1mLinDMSO
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • Manufactureraablocks
  • Product numberAA005BFX
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99%
  • Packaging1mg
  • Price$23
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005BFX
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99%
  • Packaging5mg
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005BFX
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99%
  • Packaging10mg
  • Price$78
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005BFX
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99
  • Packaging25mg
  • Price$189
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005BFX
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99
  • Packaging50mg
  • Price$308
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA005BFX
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99
  • Packaging100mg
  • Price$455
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10212
  • Product descriptionEHT 1864 98%
  • Packaging100MG
  • Price$580
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10212
  • Product descriptionEHT 1864 98%
  • Packaging25MG
  • Price$225
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number2391AH
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride
  • Packaging1mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product descriptionEHT 1864 99%
  • Packaging10mg
  • Price$98
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
  • Packaging10mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product descriptionEHT 1864 99%
  • Packaging5mg
  • Price$65
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product descriptionEHT 1864 99%
  • Packaging1mg
  • Price$29
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
  • Packaging50mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product descriptionEHT 1864 99%
  • Packaging50mg
  • Price$293
  • Updated2026-06-05
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA005BFX 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99% 1mg $23 2026-05-28 Buy
aablocks AA005BFX 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99% 5mg $52 2026-05-28 Buy
aablocks AA005BFX 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99% 10mg $78 2026-05-28 Buy
aablocks AA005BFX 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99 25mg $189 2026-05-28 Buy
aablocks AA005BFX 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99 50mg $308 2026-05-28 Buy
aablocks AA005BFX 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-one dihydrochloride 99 100mg $455 2026-05-28 Buy
ACHEMBLOCK 10212 EHT 1864 98% 100MG $580 2026-05-27 Buy
ACHEMBLOCK 10212 EHT 1864 98% 25MG $225 2026-05-27 Buy
AK Scientific 2391AH 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 1mg $82 2021-12-16 Buy
Ambeed A638191 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% 5mg $90 2021-12-16 Buy
Ambeed A638191 EHT 1864 99% 10mg $98 2026-06-05 Buy
Ambeed A638191 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% 10mg $117 2021-12-16 Buy
Ambeed A638191 EHT 1864 99% 5mg $65 2026-06-05 Buy
Ambeed A638191 EHT 1864 99% 1mg $29 2026-06-05 Buy
Ambeed A638191 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% 50mg $198 2021-12-16 Buy
Ambeed A638191 EHT 1864 99% 50mg $293 2026-06-05 Buy
Next Last

Properties

Melting point :>195°C (dec.)
storage temp. :2-8°C
solubility :H2O: soluble10mg/mL, clear
form :powder
color :white to beige
Water Solubility :H2O: 10mg/mL, clear
InChIKey :LSECOAJFCKFQJG-UHFFFAOYSA-N
SMILES :Cl.Cl.FC(F)(F)c1ccc2c(SCCCCCOC3=COC(CN4CCOCC4)=CC3=O)ccnc2c1
CAS DataBase Reference :754240-09-0

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

EHT 1864 is an inhibitor of the Rac subfamily of Rho GTPases, that binds to Rac1, Rac1b, Rac2, and Rac3 with Kd values of 40, 50, 50, and 250 nM, respectively. It can reverse transformation of NIH 3T3 fibroblasts caused by constitutively activated Rac1, as well as Rac-dependent transformation caused by Tiam1 or Ras. EHT 1864 inhibits APP processing by γ-secretase, reducing Αβ40 and Αβ42 accumulation. It blocks breast cancer cell invasion in a collagen matrix assay and, at 10 μM, increases the size but decreases the density of dendritic spines of hippocampal neurons in culture.

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Suppliers and manufacturers

career henan chemical co
EHT 1864
$1.00
EHT 1864 CAS:754240-09-0
TargetMol Chemicals Inc.
EHT 1864 2HCl
$37.00
EHT 1864 2HCl CAS:754240-09-0
ATK CHEMICAL COMPANY LIMITED
Dideu Industries Group Limited
BOC Sciences
Hefei Hirisun Pharmatech Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Golden Pharma Co., Limited
Hangzhou MolCore BioPharmatech Co.,Ltd.