Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> EHT1864

EHT1864

EHT1864 price.
  • $32 - $1423
  • Product name: EHT1864
  • CAS: 754240-09-0
  • MF: C25H27F3N2O4S2HCl
  • MW: 0
  • EINECS:
  • MDL Number:MFCD11114384
  • Synonyms:5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride;EHT 1864;2-(4-morpholinylmethyl)-5-[[5-[[7-(trifluoromethyl)-4-quinolinyl]thio]pentyl]oxy]-4H-pyran-4-one,hydrochloride (1:2);EHT 1864, >=98%;2-(morpholin-4-ylmethyl)-5-[5-[7-(trifluoromethyl)quinolin-4-yl]sulfanylpentoxy]pyran-4-one,dihydrochloride;CS-1239;CS-1343;EHT-1864;EHT-1864
23 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 250mg
  • 100mg
  • 50
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number2391AH
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride
  • Packaging1mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
  • Packaging10mg
  • Price$117
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA638191
  • Product description2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+%
  • Packaging50mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000998
  • Product descriptionEHT 1864 95.00%
  • Packaging10MG
  • Price$745.85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000998
  • Product descriptionEHT 1864 95.00%
  • Packaging50MG
  • Price$1417.71
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5487
  • Product descriptionEHT 1864
  • Packaging10mM(in 1mL DMSO)
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE103242
  • Product descriptionEHT 1864
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFE103242
  • Product descriptionEHT 1864
  • Packaging50mg
  • Price$472.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17258
  • Product descriptionEHT 1864 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17258
  • Product descriptionEHT 1864 ≥98%
  • Packaging5mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17258
  • Product descriptionEHT 1864 ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17258
  • Product descriptionEHT 1864 ≥98%
  • Packaging50mg
  • Price$911
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3154
  • Product descriptionEHT 1864 99.85%
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3154
  • Product descriptionEHT 1864 99.85%
  • Packaging10mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3154
  • Product descriptionEHT 1864 99.85%
  • Packaging50mg
  • Price$720
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2391AH 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 1mg $82 2021-12-16 Buy
Ambeed A638191 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% 5mg $90 2021-12-16 Buy
Ambeed A638191 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% 10mg $117 2021-12-16 Buy
Ambeed A638191 2-(Morpholinomethyl)-5-((5-((7-(trifluoromethyl)quinolin-4-yl)thio)pentyl)oxy)-4H-pyran-4-onedihydrochloride 98+% 50mg $198 2021-12-16 Buy
American Custom Chemicals Corporation INB0000998 EHT 1864 95.00% 10MG $745.85 2021-12-16 Buy
American Custom Chemicals Corporation INB0000998 EHT 1864 95.00% 50MG $1417.71 2021-12-16 Buy
ApexBio Technology B5487 EHT 1864 10mM(in 1mL DMSO) $115 2021-12-16 Buy
Biosynth Carbosynth FE103242 EHT 1864 10mg $135 2021-12-16 Buy
Biosynth Carbosynth FE103242 EHT 1864 50mg $472.5 2021-12-16 Buy
Cayman Chemical 17258 EHT 1864 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 17258 EHT 1864 ≥98% 5mg $121 2024-03-01 Buy
Cayman Chemical 17258 EHT 1864 ≥98% 10mg $214 2024-03-01 Buy
Cayman Chemical 17258 EHT 1864 ≥98% 50mg $911 2024-03-01 Buy
ChemScene CS-3154 EHT 1864 99.85% 5mg $108 2021-12-16 Buy
ChemScene CS-3154 EHT 1864 99.85% 10mg $156 2021-12-16 Buy
ChemScene CS-3154 EHT 1864 99.85% 50mg $720 2021-12-16 Buy

Properties

Melting point :>195°C (dec.)
storage temp. :2-8°C
solubility :H2O: soluble10mg/mL, clear
form :powder
color :white to beige
CAS DataBase Reference :754240-09-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

EHT 1864 is an inhibitor of the Rac subfamily of Rho GTPases, that binds to Rac1, Rac1b, Rac2, and Rac3 with Kd values of 40, 50, 50, and 250 nM, respectively. It can reverse transformation of NIH 3T3 fibroblasts caused by constitutively activated Rac1, as well as Rac-dependent transformation caused by Tiam1 or Ras. EHT 1864 inhibits APP processing by γ-secretase, reducing Αβ40 and Αβ42 accumulation. It blocks breast cancer cell invasion in a collagen matrix assay and, at 10 μM, increases the size but decreases the density of dendritic spines of hippocampal neurons in culture.

Related product price