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ChemicalBook >> CAS DataBase List >> ERK Inhibitor

ERK Inhibitor

ERK Inhibitor price.
  • $32 - $228
  • Product name: ERK Inhibitor
  • CAS: 1049738-54-6
  • MF: C14H17ClN2O3S
  • MW: 328.81
  • EINECS:
  • MDL Number:MFCD09038681
  • Synonyms:(5Z)-3-(2-aminoethyl)-5-[(4-ethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione:hydrochloride;ERK Inhibitor - CAS 1049738-54-6 - Calbiochem;3-(2-aminoethyl)-5-[(4-ethoxyphenyl)methylene]-2,4-thiazolidinedione,monohydrochloride
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number9473CW
  • Product descriptionErkInhibitor
  • Packaging5mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15944
  • Product descriptionERK Inhibitor ≥95%
  • Packaging500μg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15944
  • Product descriptionERK Inhibitor ≥95%
  • Packaging1mg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15944
  • Product descriptionERK Inhibitor ≥95%
  • Packaging5mg
  • Price$117
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9473CW ErkInhibitor 5mg $228 2021-12-16 Buy
Cayman Chemical 15944 ERK Inhibitor ≥95% 500μg $32 2024-03-01 Buy
Cayman Chemical 15944 ERK Inhibitor ≥95% 1mg $50 2024-03-01 Buy
Cayman Chemical 15944 ERK Inhibitor ≥95% 5mg $117 2024-03-01 Buy

Properties

storage temp. :+2C to +8C
solubility :DMSO: 2 mg/ml
form :Light yellow solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ERK inhibitor is a cell-permeable inhibitor that binds ERK2 near its docking domain (KD = 5 μM). This prevents its interaction with protein substrates without inhibiting catalytic activity. ERK inhibitor blocks ERK-specific phosphorylation of ribosomal S6 kinase-1 and ternary complex factor Elk-1 but does not affect ERK1/2 phosphorylation by MEK1/2. Presumably through its effects on ERK, ERK inhibitor completely prevents proliferation of HeLa cells (IC50 = 15-20 μM), A549 lung carcinoma cells (IC50 = 25 μM), Sum-159 estrogen receptor-negative breast cancer cells and HT1080 fibrosarcoma cells.

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Suppliers and manufacturers

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Wuhan Topule Biopharmaceutical Co., Ltd
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Aladdin Scientific Shanghai Run-Biotech Co., Ltd. Sigma-Aldrich BOC Sciences Shanghai EFE Biological Technology Co., Ltd. Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd.