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ChemicalBook >> CAS DataBase List >> Fludarabine phosphate

Fludarabine phosphate

Fludarabine phosphate price.
  • $31 - $540
  • Product name: Fludarabine phosphate
  • CAS: 75607-67-9
  • MF: C10H13FN5O7P
  • MW: 365.2116842
  • EINECS:616-242-0
  • MDL Number:MFCD00866418
  • Synonyms:((2R,3S,4S,5R)-5-(6-AMINO-2-FLUORO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE;FLUDARABINE PHOSPHATE (FLUDARABINE 5''-MONOPHOSPHATE);2-Fluoro-9-(5-O-phosphono-β-D-arabinofuranosyl)-9H-purin-6-amine;9-(5-O-Phosphono-β-D-arabinofuranosyl)-2-fluoro-9H-purine-6-amine;F-ara-AMP;9-β-Arabinofuranosyl-2-fluoroadenine-5'-monophosphate;Fludarabine Phosphate (300 mg);Fludarabine Phosphate(Fludara)
13 prices
Selected condition:

Brand

  • Alfa Aesar
  • Cayman Chemical
  • Sigma-Aldrich
  • TCI Chemical

Package

  • y0000419
  • 5mg
  • 10mg
  • 25mg
  • y0001536
  • 50mg
  • 100mg
  • 250mg
  • 300mg
  • 1g
  • ManufacturerAlfa Aesar
  • Product numberJ65154
  • Product description9-beta-D-Arabinofuranosyl-2-fluoroadenine-5'-monophosphate 99%
  • Packaging250mg
  • Price$34.8
  • Updated2020-06-24
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65154
  • Product description9-beta-D-Arabinofuranosyl-2-fluoroadenine-5'-monophosphate, 99%
  • Packaging1g
  • Price$125
  • Updated2020-06-24
  • Buy
  • ManufacturerCayman Chemical
  • Product number14251
  • Product descriptionFludarabine Phosphate ≥95%
  • Packaging5mg
  • Price$54
  • Updated2020-06-24
  • Buy
  • ManufacturerCayman Chemical
  • Product number14251
  • Product descriptionFludarabine Phosphate ≥95%
  • Packaging10mg
  • Price$91
  • Updated2020-06-24
  • Buy
  • ManufacturerCayman Chemical
  • Product number14251
  • Product descriptionFludarabine Phosphate ≥95%
  • Packaging50mg
  • Price$273
  • Updated2020-06-24
  • Buy
  • ManufacturerCayman Chemical
  • Product number14251
  • Product descriptionFludarabine Phosphate ≥95%
  • Packaging250mg
  • Price$540
  • Updated2020-06-24
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1272204
  • Product descriptionFludarabine phosphate
  • Packaging300mg
  • Price$352.8
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberF9813
  • Product descriptionFludarabine phosphate
  • Packaging5mg
  • Price$59.8
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0000419
  • Product descriptionFludarabine phosphate European Pharmacopoeia (EP) Reference Standard
  • Packagingy0000419
  • Price$183
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0001536
  • Product descriptionFludarabine for system suitability European Pharmacopoeia (EP) Reference Standard
  • Packagingy0001536
  • Price$183
  • Updated2019-12-02
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberF9813
  • Product descriptionFludarabine phosphate
  • Packaging25mg
  • Price$238
  • Updated2019-12-02
  • Buy
  • ManufacturerTCI Chemical
  • Product numberF0913
  • Product descriptionFludarabine Monophosphate >98.0%(HPLC)(T)
  • Packaging100mg
  • Price$88
  • Updated2020-06-24
  • Buy
  • ManufacturerTCI Chemical
  • Product numberF0913
  • Product descriptionFludarabine Monophosphate >98.0%(HPLC)(T)
  • Packaging25mg
  • Price$31
  • Updated2020-06-24
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J65154 9-beta-D-Arabinofuranosyl-2-fluoroadenine-5'-monophosphate 99% 250mg $34.8 2020-06-24 Buy
Alfa Aesar J65154 9-beta-D-Arabinofuranosyl-2-fluoroadenine-5'-monophosphate, 99% 1g $125 2020-06-24 Buy
Cayman Chemical 14251 Fludarabine Phosphate ≥95% 5mg $54 2020-06-24 Buy
Cayman Chemical 14251 Fludarabine Phosphate ≥95% 10mg $91 2020-06-24 Buy
Cayman Chemical 14251 Fludarabine Phosphate ≥95% 50mg $273 2020-06-24 Buy
Cayman Chemical 14251 Fludarabine Phosphate ≥95% 250mg $540 2020-06-24 Buy
Sigma-Aldrich 1272204 Fludarabine phosphate 300mg $352.8 2019-12-02 Buy
Sigma-Aldrich F9813 Fludarabine phosphate 5mg $59.8 2019-12-02 Buy
Sigma-Aldrich Y0000419 Fludarabine phosphate European Pharmacopoeia (EP) Reference Standard y0000419 $183 2019-12-02 Buy
Sigma-Aldrich Y0001536 Fludarabine for system suitability European Pharmacopoeia (EP) Reference Standard y0001536 $183 2019-12-02 Buy
Sigma-Aldrich F9813 Fludarabine phosphate 25mg $238 2019-12-02 Buy
TCI Chemical F0913 Fludarabine Monophosphate >98.0%(HPLC)(T) 100mg $88 2020-06-24 Buy
TCI Chemical F0913 Fludarabine Monophosphate >98.0%(HPLC)(T) 25mg $31 2020-06-24 Buy

Properties

Melting point: :203°C(dec.)(lit.)
alpha  :[α]D20 +10~+14゜(c=0.5,H2O)
Boiling point: :864.2±75.0 °C(Predicted)
Density  :2.39±0.1 g/cm3(Predicted)
RTECS  :UO7440900
storage temp.  :-20°C
solubility  :DMSO: soluble1mg/mL
form  :Powder
pka :1.86±0.10(Predicted)
color  :white
Water Solubility  :Soluble in DMSO or water at 5mg/ml
Merck  :14,4126
InChIKey :GIUYCYHIANZCFB-GFRUICAKSA-N
CAS DataBase Reference :75607-67-9(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

A chemotherapy drug used in the treatment of hematological malignancies. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase-?, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.

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