KN-93 Phosphate
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- $32 - $2245.7
- Product name: KN-93 Phosphate
- CAS: 1188890-41-6
- MF: C26H32ClN2O8PS
- MW: 599.032641
- EINECS:
- MDL Number:MFCD03788201
- Synonyms:KN-93PHOSPHATE;Benzenesulfonamide, N-[2-[[[(2E)-3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-, phosphate (1:1);N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4- methoxybenzenesulphonamide phosphate KN-93 Phosphate;KN-93 phosphate, >=98%;KN-93 phospate;N-[2-({[(2E)-3-(4-Chlorophenyl)-2-propen-1-yl](methyl)amino}methyl)phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide phosphate (1:1);CS-1902;N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate
22 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 2.5mg
- 1
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-0065-M005
- Product descriptionKN-93(watersoluble) ≥98%(HPLC)
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2497AH
- Product descriptionN-[2-[[[3-(4'-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4'-methoxybenzenesulfonamidephosphatesalt
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109921
- Product descriptionKN-93Phosphate 97%
- Packaging5mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109921
- Product descriptionKN-93Phosphate 97%
- Packaging10mg
- Price$82
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109921
- Product descriptionKN-93Phosphate 97%
- Packaging25mg
- Price$139
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0008622
- Product descriptionKN-93 PHOSPHATE 95.00%
- Packaging5MG
- Price$505
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4969
- Product descriptionKN-93Phosphate
- Packaging25mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2555
- Product descriptionKN93phosphate 99%
- Packaging5mg
- Price$121
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181044
- Product descriptionKN-93 Phosphate >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181044
- Product descriptionKN-93 Phosphate >98%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181044
- Product descriptionKN-93 Phosphate >98%
- Packaging1000mg
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21472
- Product descriptionKN-93 (phosphate) ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21472
- Product descriptionKN-93 (phosphate) ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21472
- Product descriptionKN-93 (phosphate) ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21472
- Product descriptionKN-93 (phosphate) ≥98%
- Packaging25mg
- Price$343
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD00012520
- Product descriptionKN-93Phosphate 97%
- Packaging50mg
- Price$295
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-0065-M005 | KN-93(watersoluble) ≥98%(HPLC) | 5mg | $95 | 2021-12-16 | Buy |
| AK Scientific | 2497AH | N-[2-[[[3-(4'-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4'-methoxybenzenesulfonamidephosphatesalt | 5mg | $104 | 2021-12-16 | Buy |
| Ambeed | A109921 | KN-93Phosphate 97% | 5mg | $59 | 2021-12-16 | Buy |
| Ambeed | A109921 | KN-93Phosphate 97% | 10mg | $82 | 2021-12-16 | Buy |
| Ambeed | A109921 | KN-93Phosphate 97% | 25mg | $139 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0008622 | KN-93 PHOSPHATE 95.00% | 5MG | $505 | 2021-12-16 | Buy |
| ApexBio Technology | B4969 | KN-93Phosphate | 25mg | $250 | 2021-12-16 | Buy |
| Axon Medchem | Axon2555 | KN93phosphate 99% | 5mg | $121 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181044 | KN-93 Phosphate >98% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181044 | KN-93 Phosphate >98% | 250mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181044 | KN-93 Phosphate >98% | 1000mg | $2245.7 | 2021-12-16 | Buy |
| Cayman Chemical | 21472 | KN-93 (phosphate) ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21472 | KN-93 (phosphate) ≥98% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 21472 | KN-93 (phosphate) ≥98% | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 21472 | KN-93 (phosphate) ≥98% | 25mg | $343 | 2024-03-01 | Buy |
| Crysdot | CD00012520 | KN-93Phosphate 97% | 50mg | $295 | 2021-12-16 | Buy |
Properties
storage temp. :Inert atmosphere,Room Temperature
solubility :DMF:25.0(Max Conc. mg/mL);41.73(Max Conc. mM)
DMSO:76.67(Max Conc. mg/mL);127.98(Max Conc. mM)
Water:49.33(Max Conc. mg/mL);82.35(Max Conc. mM) form :White to off-white solid.
color :White to off-white
Water Solubility :Soluble in water (10mM)
CAS DataBase Reference :1188890-41-6
solubility :DMF:25.0(Max Conc. mg/mL);41.73(Max Conc. mM)
DMSO:76.67(Max Conc. mg/mL);127.98(Max Conc. mM)
Water:49.33(Max Conc. mg/mL);82.35(Max Conc. mM) form :White to off-white solid.
color :White to off-white
Water Solubility :Soluble in water (10mM)
CAS DataBase Reference :1188890-41-6
Safety Information
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| Signal word: | Danger | ||||||||||||||||||||||||
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Description
KN-93 (phosphate) is a potent and selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII) (Ki = 370 nM), inhibiting both the α- and β-subunits of CaMKII. It does not have significant effects on cAMP-dependent protein kinase, Ca2+/phospholipid-dependent protein kinase, myosin light chain kinase, or Ca2+ phosphodiesterase activity. It inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 can block voltage-gated potassium (Kv) channels when applied extracellularly, independent of its CaMKII action. More recently, KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cells.More related product prices
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