Moxonidine
|
- $8 - $5000
- Product name: Moxonidine
- CAS: 75438-57-2
- MF: C9H12ClN5O
- MW: 241.68
- EINECS:629-833-3
- MDL Number:MFCD06795643
- Synonyms:MOXONIDINE;MOXONIDINE HCL;4-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamin ;bdf5895 ;be5895 ;BDF-5895 HCL;4-CHLORO-6-METHOXY-2-METHYL-5-(2-IMIDAZOLIN-2-YL)AMINOPYRIMIDINE HCL;4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMINE HYDROCHLORIDE
84 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Alichem
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 0.025g
- 0.05g
- 0.1g
- 200MG
- 0.25g
- 250.00mg
- 0.5g
- 1.00g
- 2g
- 10mM*1mLinDMSO(Solution)
- 5.00g
- 25g
- y0000226
- 50 mg
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 10g
- 10mM(in1mLDMSO)
- 5g
- 500mg
- 1g
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA005BFO
- Product descriptionMoxonidine 98%
- Packaging1mg
- Price$8
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005BFO
- Product descriptionMoxonidine 98%
- Packaging5mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005BFO
- Product descriptionMoxonidine 98%
- Packaging10mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005BFO
- Product descriptionMoxonidine 98%
- Packaging100mg
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005BFO
- Product descriptionMoxonidine 98%
- Packaging250mg
- Price$37
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005BFO
- Product descriptionMoxonidine 98%
- Packaging1g
- Price$55
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005BFO
- Product descriptionMoxonidine 98%
- Packaging5g
- Price$128
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product numberK289
- Product descriptionMoxonidine
- Packaging500mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberK289
- Product descriptionMoxonidine 98%(HPLC)
- Packaging100mg
- Price$40
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberK289
- Product descriptionMoxonidine 98%(HPLC)
- Packaging1g
- Price$102
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberK289
- Product descriptionMoxonidine 98%(HPLC)
- Packaging25mg
- Price$22
- Updated2026-06-04
- Buy
- ManufacturerAlichem
- Product number75438572
- Product description4-Chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
- Packaging250mg
- Price$286.2
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number75438572
- Product description4-Chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
- Packaging1g
- Price$688.48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA482917
- Product descriptionMoxonidine 98%
- Packaging10g
- Price$260
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA482917
- Product descriptionMoxonidine 98%
- Packaging5g
- Price$162
- Updated2026-06-05
- Buy
- ManufacturerAmbeed
- Product numberA482917
- Product descriptionMoxonidine 98%
- Packaging100mg
- Price$29
- Updated2026-06-05
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA005BFO | Moxonidine 98% | 1mg | $8 | 2026-05-28 | Buy |
| aablocks | AA005BFO | Moxonidine 98% | 5mg | $10 | 2026-05-28 | Buy |
| aablocks | AA005BFO | Moxonidine 98% | 10mg | $12 | 2026-05-28 | Buy |
| aablocks | AA005BFO | Moxonidine 98% | 100mg | $23 | 2026-05-28 | Buy |
| aablocks | AA005BFO | Moxonidine 98% | 250mg | $37 | 2026-05-28 | Buy |
| aablocks | AA005BFO | Moxonidine 98% | 1g | $55 | 2026-05-28 | Buy |
| aablocks | AA005BFO | Moxonidine 98% | 5g | $128 | 2026-05-28 | Buy |
| AK Scientific | K289 | Moxonidine | 500mg | $220 | 2021-12-16 | Buy |
| AK Scientific | K289 | Moxonidine 98%(HPLC) | 100mg | $40 | 2026-06-04 | Buy |
| AK Scientific | K289 | Moxonidine 98%(HPLC) | 1g | $102 | 2026-06-04 | Buy |
| AK Scientific | K289 | Moxonidine 98%(HPLC) | 25mg | $22 | 2026-06-04 | Buy |
| Alichem | 75438572 | 4-Chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine | 250mg | $286.2 | 2021-12-16 | Buy |
| Alichem | 75438572 | 4-Chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine | 1g | $688.48 | 2021-12-16 | Buy |
| Ambeed | A482917 | Moxonidine 98% | 10g | $260 | 2026-06-05 | Buy |
| Ambeed | A482917 | Moxonidine 98% | 5g | $162 | 2026-06-05 | Buy |
| Ambeed | A482917 | Moxonidine 98% | 100mg | $29 | 2026-06-05 | Buy |
Properties
Melting point :217-219° (dec)
Boiling point :364.7±52.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Very slightly soluble in water, sparingly soluble in methanol, slightly soluble in methylene chloride, very slightly soluble in acetonitrile.
form :Solid
pka :7.11±0.10(Predicted)
color :White to Almost white
Water Solubility :800.3mg/L(temperature not stated)
Merck :14,6293
Major Application :pharmaceutical (small molecule)
InChI :1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15)
InChIKey :WPNJAUFVNXKLIM-UHFFFAOYSA-N
SMILES :Clc1nc(nc(c1N=C2NCCN2)OC)C
CAS DataBase Reference :75438-57-2(CAS DataBase Reference)
Boiling point :364.7±52.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Very slightly soluble in water, sparingly soluble in methanol, slightly soluble in methylene chloride, very slightly soluble in acetonitrile.
form :Solid
pka :7.11±0.10(Predicted)
color :White to Almost white
Water Solubility :800.3mg/L(temperature not stated)
Merck :14,6293
Major Application :pharmaceutical (small molecule)
InChI :1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15)
InChIKey :WPNJAUFVNXKLIM-UHFFFAOYSA-N
SMILES :Clc1nc(nc(c1N=C2NCCN2)OC)C
CAS DataBase Reference :75438-57-2(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Moxonidine, also known as Physiotens, is a highly selective imidazoline receptor agonist-Ⅰ by excitement ventrolateral medulla nucleus (RVLM)-Ⅰ type imidazoline receptor in the peripheral sympathetic nerve activity decreased. This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata.Moxonidine therefore causes a decrease in sympathetic nervous system activity and, therefore, a decrease in blood pressure.
It is a new type of antihypertensive drug, commonly used in the treatment of essential hypertension. Compared to the older central-acting antihypertensives, moxonidine binds with much greater affinity to the imidazoline I1-receptor than to the α2-receptor. In contrast, clonidine binds to both receptors with equal affinity.
It may have a role when thiazides, beta-blockers, ACE inhibitors and calcium channel blockers are not appropriate or have failed to control blood pressure.
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Suppliers and manufacturers
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
TCI (Shanghai) Development Co., Ltd.
Jia Xing Isenchem Co.,Ltd
Pure Chemistry Scientific Inc.
Adamas Reagent, Ltd.
LGM Pharma
Chemsky（shanghai）International Co.,Ltd.
XiaoGan ShenYuan ChemPharm co,ltd
Daicel Chiral Technologies (China)CO.,LTD