PD 0325901
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- $8 - $1680
- Product name: PD 0325901
- CAS: 391210-10-9
- MF: C16H14F3IN2O4
- MW: 482.19
- EINECS:687-152-7
- MDL Number:MFCD08435926
- Synonyms:N-[(2R)-2,3-DIHYDROXYPROPOXY]-3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMINO]-BENZAMIDE;PD 0325901;(R)-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide;PD-0235901;N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]be;N-[(R)-2,3 -Dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodo-phenylaMino)-benzaMide;N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide PD0325901;PD 0325901 N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
50 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- Usbiological
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 10
- 50
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3711-M005
- Product descriptionPD 0325901 ≥98%(HPLC)
- Packaging5mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberW5947
- Product description(R)-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberW5947
- Product description(R)-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA370482
- Product description(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98%
- Packaging1mg
- Price$8
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA370482
- Product description(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98%
- Packaging5mg
- Price$18
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA370482
- Product description(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98%
- Packaging10mg
- Price$26
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA370482
- Product description(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98%
- Packaging25mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA370482
- Product description(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98%
- Packaging100mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA370482
- Product description(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98%
- Packaging250mg
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA370482
- Product description(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98%
- Packaging1g
- Price$401
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007709
- Product descriptionPD 0325901 95.00%
- Packaging1MG
- Price$200.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007709
- Product descriptionPD 0325901 95.00%
- Packaging5MG
- Price$523
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007709
- Product descriptionPD 0325901 95.00%
- Packaging100MG
- Price$1144.61
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3013
- Product descriptionPD 0325901
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3013
- Product descriptionPD 0325901
- Packaging25mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60032
- Product descriptionPD0325901(Mirdametinib)
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3711-M005 | PD 0325901 ≥98%(HPLC) | 5mg | $45 | 2021-12-16 | Buy |
| AK Scientific | W5947 | (R)-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide | 5mg | $80 | 2021-12-16 | Buy |
| AK Scientific | W5947 | (R)-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide | 10mg | $135 | 2021-12-16 | Buy |
| Ambeed | A370482 | (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98% | 1mg | $8 | 2021-12-16 | Buy |
| Ambeed | A370482 | (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98% | 5mg | $18 | 2021-12-16 | Buy |
| Ambeed | A370482 | (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98% | 10mg | $26 | 2021-12-16 | Buy |
| Ambeed | A370482 | (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98% | 25mg | $44 | 2021-12-16 | Buy |
| Ambeed | A370482 | (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98% | 100mg | $98 | 2021-12-16 | Buy |
| Ambeed | A370482 | (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98% | 250mg | $159 | 2021-12-16 | Buy |
| Ambeed | A370482 | (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide 98% | 1g | $401 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007709 | PD 0325901 95.00% | 1MG | $200.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007709 | PD 0325901 95.00% | 5MG | $523 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007709 | PD 0325901 95.00% | 100MG | $1144.61 | 2021-12-16 | Buy |
| ApexBio Technology | A3013 | PD 0325901 | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A3013 | PD 0325901 | 25mg | $150 | 2021-12-16 | Buy |
| Arctom | CFN60032 | PD0325901(Mirdametinib) | 10mg | $218 | 2021-12-16 | Buy |
Properties
Melting point :112-114°C
Density :1.817±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :White to off-white solid
pka :13.45±0.20(Predicted)
color :white to off-white
optical activity :[α]/D -1.8 to -3.5°, c = 1 mg/mL in methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :SUDAHWBOROXANE-SECBINFHSA-N
Density :1.817±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :White to off-white solid
pka :13.45±0.20(Predicted)
color :white to off-white
optical activity :[α]/D -1.8 to -3.5°, c = 1 mg/mL in methanol
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :SUDAHWBOROXANE-SECBINFHSA-N
Safety Information
| Symbol(GHS): |
 
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Description
The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. PD 0325901 is a potent MEK inhibitor that suppresses phosphorylation of ERK in mouse colon 26 tumors with an IC50 value of 0.33 nM. Suppression of ERK activation with 1 μM PD 0325901 combined with 3 μM CHIR99021 (a glycogen synthase kinase 3 inhibitor) prevents cell differentiation and sustains self renewal of mouse embryonic stem cells for at least eight passages.Related product price
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