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ChemicalBook >> CAS DataBase List >> ReModelin hydrobroMide

ReModelin hydrobroMide

ReModelin hydrobroMide price.
  • $37 - $1125
  • Product name: ReModelin hydrobroMide
  • CAS: 1622921-15-6
  • MF: C15H15BrN4S
  • MW: 363.2754
  • EINECS:
  • MDL Number:MFCD28137688
  • Synonyms:ReModelin hydrobroMide;Remodelin HBR;4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile, hydrobromide (1:1);Remodelin 16066 Remodelin (hydrobromide) 4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile;Benzonitrile, 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-, hydrobromide (1:1);CS-1751;4-[2-(2-cyclopentylidenehydrazinyl)-1,3-thiazol-4-yl]benzonitrile;ReModelin hydrobroMide USP/EP/BP
22 prices
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Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number4002AH
  • Product descriptionRemodelin hydrobromide
  • Packaging5mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4002AH
  • Product descriptionRemodelin hydrobromide
  • Packaging10mg
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171428
  • Product descriptionRemodelin hydrobromide 98+%
  • Packaging5mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171428
  • Product descriptionRemodelin hydrobromide 98+%
  • Packaging10mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171428
  • Product descriptionRemodelin hydrobromide 98+%
  • Packaging25mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171428
  • Product descriptionRemodelin hydrobromide 98+%
  • Packaging50mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171428
  • Product descriptionRemodelin hydrobromide 98+%
  • Packaging100mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA171428
  • Product descriptionRemodelin hydrobromide 98+%
  • Packaging250mg
  • Price$261
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4887
  • Product descriptionRemodelin
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16066
  • Product descriptionRemodelin (hydrobromide) ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16066
  • Product descriptionRemodelin (hydrobromide) ≥98%
  • Packaging5mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16066
  • Product descriptionRemodelin (hydrobromide) ≥98%
  • Packaging10mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM161469
  • Product description4-(2-(2-cyclopentylidenehydrazinyl)thiazol-4-yl)benzonitrilehydrobromide 98%
  • Packaging50mg
  • Price$373
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3459
  • Product descriptionRemodelin hydrobromide 99.49%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3459
  • Product descriptionRemodelin hydrobromide 99.49%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003142
  • Product descriptionRemodelin hydrobromide 98+%
  • Packaging50mg
  • Price$260
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4002AH Remodelin hydrobromide 5mg $118 2021-12-16 Buy
AK Scientific 4002AH Remodelin hydrobromide 10mg $153 2021-12-16 Buy
Ambeed A171428 Remodelin hydrobromide 98+% 5mg $51 2021-12-16 Buy
Ambeed A171428 Remodelin hydrobromide 98+% 10mg $67 2021-12-16 Buy
Ambeed A171428 Remodelin hydrobromide 98+% 25mg $88 2021-12-16 Buy
Ambeed A171428 Remodelin hydrobromide 98+% 50mg $115 2021-12-16 Buy
Ambeed A171428 Remodelin hydrobromide 98+% 100mg $173 2021-12-16 Buy
Ambeed A171428 Remodelin hydrobromide 98+% 250mg $261 2021-12-16 Buy
ApexBio Technology B4887 Remodelin 100mg $550 2021-12-16 Buy
Cayman Chemical 16066 Remodelin (hydrobromide) ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 16066 Remodelin (hydrobromide) ≥98% 5mg $161 2024-03-01 Buy
Cayman Chemical 16066 Remodelin (hydrobromide) ≥98% 10mg $283 2024-03-01 Buy
Chemenu CM161469 4-(2-(2-cyclopentylidenehydrazinyl)thiazol-4-yl)benzonitrilehydrobromide 98% 50mg $373 2021-12-16 Buy
ChemScene CS-3459 Remodelin hydrobromide 99.49% 5mg $60 2021-12-16 Buy
ChemScene CS-3459 Remodelin hydrobromide 99.49% 10mg $90 2021-12-16 Buy
Crysdot CD31003142 Remodelin hydrobromide 98+% 50mg $260 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :≥36.3 mg/mL in DMSO; insoluble in H2O; ≥2.6 mg/mL in EtOH with ultrasonic
form :Powder

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 μM, improves nuclear architecture, chromatin organization, and survival of both cells lacking lamin A and cells from patients with progeria. Remodelin is an inhibitor of N-acetyltransferase 10 (NAT10), which acetylates both histones and microtubules. Mutation of NAT10 mimics the effects of remodelin on nuclear morphology, suggesting that these effects of remodelin require NAT10. Remodelin also has cytotoxic effects against some species of the fungus Candida.

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