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ChemicalBook >> CAS DataBase List >> SGK1 Inhibitor

SGK1 Inhibitor

SGK1 Inhibitor price.
  • $37 - $704
  • Product name: SGK1 Inhibitor
  • CAS: 1426214-51-8
  • MF: C17H12Cl2N6O2S
  • MW: 435.29
  • EINECS:
  • MDL Number:
  • Synonyms:Benzenesulfonamide, N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichloro-;N-[4-(3-amino-1H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichloro-benzenesulfonamide
5 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number9244DU
  • Product descriptionN-[4-(3-Amino-2H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichlorobenzenesulfonamide
  • Packaging10mg
  • Price$452
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25652
  • Product descriptionSGK1 Inhibitor
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25652
  • Product descriptionSGK1 Inhibitor
  • Packaging5mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25652
  • Product descriptionSGK1 Inhibitor
  • Packaging10mg
  • Price$319
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25652
  • Product descriptionSGK1 Inhibitor
  • Packaging25mg
  • Price$704
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9244DU N-[4-(3-Amino-2H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,3-dichlorobenzenesulfonamide 10mg $452 2021-12-16 Buy
Cayman Chemical 25652 SGK1 Inhibitor 1mg $37 2024-03-01 Buy
Cayman Chemical 25652 SGK1 Inhibitor 5mg $169 2024-03-01 Buy
Cayman Chemical 25652 SGK1 Inhibitor 10mg $319 2024-03-01 Buy
Cayman Chemical 25652 SGK1 Inhibitor 25mg $704 2024-03-01 Buy

Properties

Boiling point :730.5±70.0 °C(Predicted)
Density :1.660±0.06 g/cm3(Predicted)
solubility :DMSO: soluble
form :A solid
pka :5.86±0.10(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3β in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kα inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719.