SU 6668
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- $5 - $1350
- Product name: SU 6668
- CAS: 210644-62-5
- MF: C18H18N2O3
- MW: 310.35
- EINECS:
- MDL Number:MFCD09743433
- Synonyms:SU 6668;3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)-propionic acid;1H-Pyrrole-3-propanoic acid, 5-((Z)-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-;5-((Z)-1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-propanoic acid;PDGFR Tyrosine Kinase Inhibitor VI, SU6668;3-[2,4-dimethyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoicacid;PDGFR Tyrosine Kinase Inhibitor VI, SU6668 - CAS 210644-62-5 - Calbiochem;3-(2,4-Dimethyl-5-{[(3Z)-2-oxo-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid
34 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Ambeed
- AvaChem
- Axon Medchem
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 10
- 5mg
- 25mg
- 50mg
- 100mg
- 250MG
- 250.00mg
- 1.00g
- 1G
- 5g
- Manufactureraablocks
- Product numberAA002KTY
- Product descriptionSU6668 >98%
- Packaging50mg
- Price$235
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002KTY
- Product descriptionSU6668 >98%
- Packaging100mg
- Price$335
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002KTY
- Product descriptionSU6668 >98%
- Packaging10mg
- Price$102
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002KTY
- Product descriptionSU6668 >98%
- Packaging5mg
- Price$78
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD266324
- Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid 95%
- Packaging250MG
- Price$330
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD266324
- Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid 95%
- Packaging1G
- Price$990
- Updated2026-05-27
- Buy
- ManufacturerAmbeed
- Product numberA146183
- Product descriptionSU6668 97%
- Packaging5g
- Price$405
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA146183
- Product descriptionSU6668 97%
- Packaging25mg
- Price$5
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number4723
- Product descriptionOrantinib; SU-6668 97%
- Packaging5mg
- Price$59
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number4723
- Product descriptionOrantinib; SU-6668 97%
- Packaging10mg
- Price$79
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number4723
- Product descriptionOrantinib; SU-6668 97%
- Packaging25mg
- Price$129
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number4723
- Product descriptionOrantinib; SU-6668 97%
- Packaging100mg
- Price$239
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number4723
- Product descriptionOrantinib; SU-6668 97%
- Packaging1g
- Price$690
- Updated2026-05-22
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1891
- Product descriptionSU 6668
- Packaging50mg
- Price$363
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1891
- Product descriptionSU 6668
- Packaging10mg
- Price$110
- Updated2026-05-19
- Buy
- ManufacturerChemenu
- Product numberCM147636
- Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoic acid 95%+
- Packaging5g
- Price$292
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002KTY | SU6668 >98% | 50mg | $235 | 2026-05-28 | Buy |
| aablocks | AA002KTY | SU6668 >98% | 100mg | $335 | 2026-05-28 | Buy |
| aablocks | AA002KTY | SU6668 >98% | 10mg | $102 | 2026-05-28 | Buy |
| aablocks | AA002KTY | SU6668 >98% | 5mg | $78 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD266324 | (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid 95% | 250MG | $330 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD266324 | (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid 95% | 1G | $990 | 2026-05-27 | Buy |
| Ambeed | A146183 | SU6668 97% | 5g | $405 | 2021-12-16 | Buy |
| Ambeed | A146183 | SU6668 97% | 25mg | $5 | 2021-12-16 | Buy |
| AvaChem | 4723 | Orantinib; SU-6668 97% | 5mg | $59 | 2026-05-22 | Buy |
| AvaChem | 4723 | Orantinib; SU-6668 97% | 10mg | $79 | 2026-05-22 | Buy |
| AvaChem | 4723 | Orantinib; SU-6668 97% | 25mg | $129 | 2026-05-22 | Buy |
| AvaChem | 4723 | Orantinib; SU-6668 97% | 100mg | $239 | 2026-05-22 | Buy |
| AvaChem | 4723 | Orantinib; SU-6668 97% | 1g | $690 | 2026-05-22 | Buy |
| Axon Medchem | Axon1891 | SU 6668 | 50mg | $363 | 2026-05-19 | Buy |
| Axon Medchem | Axon1891 | SU 6668 | 10mg | $110 | 2026-05-19 | Buy |
| Chemenu | CM147636 | (Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoic acid 95%+ | 5g | $292 | 2026-05-26 | Buy |
Properties
Melting point :265-267 °C
Boiling point :590.477±50.00 °C(Press: 760.00 Torr)(predicted)
Density :1.328±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :+2C to +8C
solubility :DMSO : 50 mg/mL (161.11 mM; Need ultrasonic)
form :Dark yellow solid
pka :4.625±0.10(predicted)
color :Orange to red
InChI :1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
InChIKey :NHFDRBXTEDBWCZ-ZROIWOOFSA-N
SMILES :CC1=C(C(C)=C(/C=C2C(NC3=CC=CC=C\23)=O)N1)CCC(O)=O
Boiling point :590.477±50.00 °C(Press: 760.00 Torr)(predicted)
Density :1.328±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. :+2C to +8C
solubility :DMSO : 50 mg/mL (161.11 mM; Need ultrasonic)
form :Dark yellow solid
pka :4.625±0.10(predicted)
color :Orange to red
InChI :1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
InChIKey :NHFDRBXTEDBWCZ-ZROIWOOFSA-N
SMILES :CC1=C(C(C)=C(/C=C2C(NC3=CC=CC=C\23)=O)N1)CCC(O)=O
Safety Information
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Description
PDGFR Tyrosine Kinase Inhibitor VI, SU6668 is a cell-permeable indolinone compound that acts as a potent ATP-competitive inhibitor against RTKs (receptor tyrosine kinases) Kit, PDGFRβ, VEGFR2 (Flk-1/KDR), FGFR1 activity in vitro (IC50 = 0.01, 0.1, 3.9, and 3.8 M, respectively) and PDGF/VEGF/bFGF-mediated angiogenesis and tumor development. Although initially characterized as an RTK inhibitor, SU6668 is now also known to target ser/thr kinases Aurora A, Aurora B, TBK1 (NAK/T2K), and AMPK (IC50 = 0.85, 0.047, 1.4, and 1.8 M, respectively), as well as non-receptor TKs Lyn and Yes (IC50 = 4.3 and 5.8 M, respectively).More related product prices
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