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ChemicalBook >> CAS DataBase List >> TOPOTECAN-D6

TOPOTECAN-D6

TOPOTECAN-D6 price.
  • $140 - $1871.1
  • Product name: TOPOTECAN-D6
  • CAS: 1044904-10-0
  • MF: C23H23N3O5
  • MW: 421.45
  • EINECS:
  • MDL Number:
  • Synonyms:TOPOTECAN-D6;(4S)-10-[[Di(methyl-d3)amino]methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[346-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;SKF-104864A-d6;(4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3’,4’,6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Hycamtin-d6;NSC-609669-d6;(4S)-10-[[Di(methyl-d3)amino]methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;[2H6]-Topotecan
8 prices
Selected condition:

Brand

  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological

Package

  • 500μg
  • 1MG
  • 10MG
  • 100MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0005320
  • Product descriptionTOPOTECAN-D6 95.00%
  • Packaging1MG
  • Price$545
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0005320
  • Product descriptionTOPOTECAN-D6 95.00%
  • Packaging10MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0005320
  • Product descriptionTOPOTECAN-D6 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29082
  • Product descriptionTopotecan-d6
  • Packaging500μg
  • Price$140
  • Updated2023-01-06
  • Buy
  • ManufacturerCayman Chemical
  • Product number29082
  • Product descriptionTopotecan-d6
  • Packaging1mg
  • Price$266
  • Updated2023-01-06
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product numberD4415
  • Product descriptionTopotecan-d6
  • Packaging1mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT542502
  • Product descriptionTopotecan-d6
  • Packaging10mg
  • Price$1455
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberT8067-11
  • Product descriptionTopotecan-d6
  • Packaging1mg
  • Price$460
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation RDL0005320 TOPOTECAN-D6 95.00% 1MG $545 2021-12-16 Buy
American Custom Chemicals Corporation RDL0005320 TOPOTECAN-D6 95.00% 10MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation RDL0005320 TOPOTECAN-D6 95.00% 100MG $1871.1 2021-12-16 Buy
Cayman Chemical 29082 Topotecan-d6 500μg $140 2023-01-06 Buy
Cayman Chemical 29082 Topotecan-d6 1mg $266 2023-01-06 Buy
Medical Isotopes, Inc. D4415 Topotecan-d6 1mg $750 2021-12-16 Buy
TRC T542502 Topotecan-d6 10mg $1455 2021-12-16 Buy
Usbiological T8067-11 Topotecan-d6 1mg $460 2021-12-16 Buy

Properties

Melting point :213-218°C (dec)
storage temp. :-20°C Freezer
CAS DataBase Reference :1044904-10-0

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Topotecan-d6 is intended for use as an internal standard for the quantification of topotecan by GC- or LC-MS. Topotecan is an inhibitor of DNA topoisomerase I and a derivative of the DNA topoisomerase I inhibitor camptothecin . Topotecan inhibits DNA topoisomerase I in human MCF-7 breast and DU145 prostate cancer cells with IC50 values of 13 and 2 nM, respectively, in a cell-based luciferase reporter assay. Topotecan induces cytotoxicity and DNA damage in HT-29 human colon adenocarcinoma cells (IC50s = 33 and 280 nM, respectively). Formulations containing topotecan have been used in the treatment of small-cell lung cancer.

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