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ChemicalBook >> CAS DataBase List >> Trichloroacetic acid

Trichloroacetic acid

Trichloroacetic acid price.
  • $14 - $4601
  • Product name: Trichloroacetic acid
  • CAS: 76-03-9
  • MF: C2HCl3O2
  • MW: 163.39
  • EINECS:200-927-2
  • MDL Number:MFCD00004177
  • Synonyms:Deblock trichloroacetic acid solution;TRICHLOROACETIC ACID extrapure;RARECHEM AL BO 0072;Aceticacid,trichloro- ;Aceto-Caustin;Acide trichloracetique;acidetrichloracetique ;acidetrichloracetique(french)
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  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid
  • Packaging25g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberS221
  • Product descriptionTrichloroacetic acid
  • Packaging1kg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product number022156
  • Product descriptionTrichloroacetic acid, ACS 99% min
  • Packaging50g
  • Price$30.2
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberA11156
  • Product descriptionTrichloroacetic acid 99%
  • Packaging250g
  • Price$48.2
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ62366
  • Product descriptionTrichloroacetic acid 5% w/v aq. soln.
  • Packaging500ml
  • Price$72.5
  • Updated2023-06-20
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  • ManufacturerAlfa Aesar
  • Product numberA11156
  • Product descriptionTrichloroacetic acid 99%
  • Packaging500g
  • Price$78.7
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ62355
  • Product descriptionTrichloroacetic acid 10% w/v aq. soln.
  • Packaging500ml
  • Price$104
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ62366
  • Product descriptionTrichloroacetic acid 5% w/v aq. soln.
  • Packaging1L
  • Price$106.05
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product number022156
  • Product descriptionTrichloroacetic acid, ACS 99% min
  • Packaging250g
  • Price$107
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA11156
  • Product descriptionTrichloroacetic acid 99%
  • Packaging1000g
  • Price$133
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product number022156
  • Product descriptionTrichloroacetic acid, ACS 99% min
  • Packaging1kg
  • Price$351
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberA11156
  • Product descriptionTrichloroacetic acid 99%
  • Packaging5000g
  • Price$508
  • Updated2024-03-01
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  • ManufacturerChem-Impex
  • Product number00820
  • Product descriptionTrichloroacetic acid ≥ 99.0% (Titration)
  • Packaging100G
  • Price$25
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number00820
  • Product descriptionTrichloroacetic acid ≥ 99.0% (Titration)
  • Packaging250G
  • Price$50
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number00820
  • Product descriptionTrichloroacetic acid ≥ 99.0% (Titration)
  • Packaging1KG
  • Price$95
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number00820
  • Product descriptionTrichloroacetic acid ≥ 99.0% (Titration)
  • Packaging5KG
  • Price$425
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific S221 Trichloroacetic acid 25g $14 2021-12-16 Buy
AK Scientific S221 Trichloroacetic acid 1kg $102 2021-12-16 Buy
Alfa Aesar 022156 Trichloroacetic acid, ACS 99% min 50g $30.2 2024-03-01 Buy
Alfa Aesar A11156 Trichloroacetic acid 99% 250g $48.2 2024-03-01 Buy
Alfa Aesar J62366 Trichloroacetic acid 5% w/v aq. soln. 500ml $72.5 2023-06-20 Buy
Alfa Aesar A11156 Trichloroacetic acid 99% 500g $78.7 2024-03-01 Buy
Alfa Aesar J62355 Trichloroacetic acid 10% w/v aq. soln. 500ml $104 2024-03-01 Buy
Alfa Aesar J62366 Trichloroacetic acid 5% w/v aq. soln. 1L $106.05 2023-06-20 Buy
Alfa Aesar 022156 Trichloroacetic acid, ACS 99% min 250g $107 2024-03-01 Buy
Alfa Aesar A11156 Trichloroacetic acid 99% 1000g $133 2024-03-01 Buy
Alfa Aesar 022156 Trichloroacetic acid, ACS 99% min 1kg $351 2024-03-01 Buy
Alfa Aesar A11156 Trichloroacetic acid 99% 5000g $508 2024-03-01 Buy
Chem-Impex 00820 Trichloroacetic acid ≥ 99.0% (Titration) 100G $25 2021-12-16 Buy
Chem-Impex 00820 Trichloroacetic acid ≥ 99.0% (Titration) 250G $50 2021-12-16 Buy
Chem-Impex 00820 Trichloroacetic acid ≥ 99.0% (Titration) 1KG $95 2021-12-16 Buy
Chem-Impex 00820 Trichloroacetic acid ≥ 99.0% (Titration) 5KG $425 2021-12-16 Buy

Properties

Melting point :54-58 °C (lit.)
Boiling point :196 °C (lit.)
Density :1.62 g/mL at 25 °C (lit.)
vapor density :<1 (vs air)
vapor pressure :1 mm Hg ( 51 °C)
refractive index :n20/D 1.62(lit.)
Flash point :196°C
storage temp. :Store at +15°C to +25°C.
solubility :H2O: 0.5 M at 20 °C, clear, colorless
pka :0.7(at 25℃)
form :Solid
color :White
PH :<1.0 (25℃, 0.5M in H2O)
Odor :sharp, pungent odor
Water Solubility :120 g/100 mL (20 ºC)
Sensitive :Hygroscopic
λmax :210nm(EtOH)(lit.)
Merck :14,9627
BRN :970119
Dielectric constant :4.9(20℃)
Exposure limits :ACGIH: TWA 0.5 ppm
NIOSH: TWA 1 ppm(7 mg/m3) Stability :Stable, but moisture sensitive. Incompatible with water, strong bases. Note that the Merck Index states that this material is hydrolytically unstable in aqueous solution below 30% by weight. Decomposition products include carbon monoxide and carbon dioxide. The generation of these gases in a sealed container may lead to a pressure rise sufficien
LogP :1.330
CAS DataBase Reference :76-03-9(CAS DataBase Reference)
IARC :2B (Vol. 63, 84, 106) 2014
NIST Chemistry Reference :Acetic acid, trichloro-(76-03-9)
EPA Substance Registry System :Trichloroacetic acid (76-03-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Trichloroacetic acid (TCA) is a kind of acetate analogue with the three hydrogen atoms of the methyl group in acetate being replaced by chlorine atoms. It is a strong acid which can be used in protein precipitation in clinical chemistry and biochemistry as well as a caustic for warts removal. It can be synthesize through the reaction between chlorine and acetate in the presence of a suitable catalyst, or alternatively by the oxidation of trichloroacetaldehyde. In addition to protein precipitation, it can also be used for RNA and DNA precipitation. Its sodium salt can also be used as a herbicide.

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