- 4-(3-Chloropropyl)morpholine
-
- $8.00 / 1KG
-
2024-01-14
- CAS:7357-67-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
|
| | 4-(3-Chloropropyl)morpholine Basic information |
| | 4-(3-Chloropropyl)morpholine Chemical Properties |
| Melting point | NA | | Boiling point | 115°C/25mmHg(lit.) | | density | 1.0409 g/cm3 | | RTECS | QE0488000 | | refractive index | 1.4720-1.4760 | | Fp | 91 °C | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Oil | | pka | 7.03±0.10(Predicted) | | Specific Gravity | 1.08 | | color | Colourless to Yellow | | InChI | InChI=1S/C7H14ClNO/c8-2-1-3-9-4-6-10-7-5-9/h1-7H2 | | InChIKey | PQECODMSWJOUAT-UHFFFAOYSA-N | | SMILES | N1(CCCCl)CCOCC1 | | CAS DataBase Reference | 7357-67-7(CAS DataBase Reference) |
| | 4-(3-Chloropropyl)morpholine Usage And Synthesis |
| Description | 4-(3-Chloropropyl)morpholine is a hydrochloride salt of the potent inhibitor 4-(3-chloropropyl)morpholine. It has an inhibitory effect on cancer, and is used in chromatographic science to separate amines from aliphatic hydrocarbons. 4-(3-Chloropropyl)morpholine inhibits epidermal growth factor (EGF) and has been shown to have a potent inhibitory effect on EGF receptor tyrosine kinase activity. It also inhibits the proliferation of cells by inhibiting DNA synthesis. This compound causes cell death through the inhibition of protein synthesis, which may be due to its ability to inhibit nucleophilic reactions that are involved in protein synthesis. 4-(3-Chloropropyl)morpholine can also fluoresce under UV light, which makes it useful for research purposes. | | Chemical Properties | Pale Yellow Oil | | Uses | Gefitinib intermediate. | | Application | 4-(3-Chloropropyl)morpholine is an organic synthetic reagent or pharmaceutical intermediate used in the synthesis of gefitinib. It has cancer-inhibiting properties and inhibits epidermal growth factor (EGF). It also inhibits cell proliferation by inhibiting DNA synthesis. |
| | 4-(3-Chloropropyl)morpholine Preparation Products And Raw materials |
|