- FMoc-Val-Cit-PAB
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- $10.00 / 1kg
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2024-05-24
- CAS:159858-22-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20ton
- Fmoc-Val-Cit-PAB-OH
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- $0.00 / 10g
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2024-03-29
- CAS:159858-22-7
- Min. Order: 10g
- Purity: >95.00%
- Supply Ability: 10g
- FMoc-Val-Cit-PAB
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- $0.00 / 1KG
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2022-10-14
- CAS:159858-22-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1Ton
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| FMoc-Val-Cit-PAB Basic information | Uses |
Product Name: | FMoc-Val-Cit-PAB | Synonyms: | FMoc-Val-Cit-PAB;L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-;(9H-fluoren-9-yl)methyl((S)-1-((())-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;(9H-fluoren-9-yl)methyl N-[(1S)-1-{[(1S)-4-(carbamoylamino)-1-{[4-(hydroxymethyl)phenyl]carbamoyl}butyl]carbamoyl}-2-methylpropyl]carbamate;Fmoc-val-citrulline-para-aminobenzyl-OH;(9H-fluoren-9-yl)methyl ((2S)-1-((1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;4-(N-((9H-fluoren-9-yl)methoxycarbonyl)-L-valinyl-D-citrullinamido)benzyl alcohol;Fmoc-Val-Cit-PAB-OH | CAS: | 159858-22-7 | MF: | C33H39N5O6 | MW: | 601.69 | EINECS: | | Product Categories: | ADCs;ADC Linker;ADC-Linker;ADC-Linkers | Mol File: | 159858-22-7.mol | |
| FMoc-Val-Cit-PAB Chemical Properties |
Melting point | 204 °C(dec.) | Boiling point | 914.2±65.0 °C(Predicted) | density | 1.276±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Store in freezer, under -20°C | form | powder to crystal | pka | 10.63±0.46(Predicted) | color | White to Almost white | CAS DataBase Reference | 159858-22-7 |
| FMoc-Val-Cit-PAB Usage And Synthesis |
Uses | Fmoc-Val-Cit-PAB is a commonly used bridge for a degradable antibody-conjugated drug (ADC).
| Description | Fmoc-Val-Cit-PAB-OH is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. Fmoc can be deprotected under basic condition. |
| FMoc-Val-Cit-PAB Preparation Products And Raw materials |
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