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| | Tetramethylammonium acetate Basic information |
| Product Name: | Tetramethylammonium acetate | | Synonyms: | TETRAMETHYLAMMONIUM ACETATE;n,n,n-trimethyl-methanaminiuacetate;TETRAMETHYLAMMONIUM ACETATE, 90% TECH.;Tetramethylammonium acetate, 50% aqueous solution;METHANAMINIUM,N,N,N-TRIMETHYL-,ACETATE;Tetramethylammonium Acetate (ca. 15% in Water);Tetramethylammonium acetate, tech. 90%;TetraMethylaMMoniuM acetate Monohydrate | | CAS: | 10581-12-1 | | MF: | C6H15NO2 | | MW: | 133.19 | | EINECS: | 234-179-3 | | Product Categories: | quarternary ammonium salts;Ammonium Polyhalides, etc. (Quaternary);Quaternary Ammonium Compounds;Ammonium Salts;Greener Alternatives: Catalysis;Phase Transfer Catalysts;bc0001 | | Mol File: | 10581-12-1.mol |  |
| | Tetramethylammonium acetate Chemical Properties |
| Melting point | 184 °C (dec.) (lit.) | | density | 1.000g/cm3 at 20°C | | storage temp. | Store below +30°C. | | form | Crystalline Solid | | color | White | | Water Solubility | Soluble in water. | | Sensitive | Hygroscopic | | BRN | 3571830 | | InChI | InChI=1S/C4H12N.C2H4O2/c1-5(2,3)4;1-2(3)4/h1-4H3;1H3,(H,3,4)/q+1;/p-1 | | InChIKey | MRYQZMHVZZSQRT-UHFFFAOYSA-M | | SMILES | [N+](C)(C)(C)C.C(=O)([O-])C | | CAS DataBase Reference | 10581-12-1(CAS DataBase Reference) | | EPA Substance Registry System | Methanaminium, N,N,N-trimethyl-, acetate (10581-12-1) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-22 | | Safety Statements | 26-36-37/39 | | WGK Germany | 3 | | F | 3-10 | | TSCA | TSCA listed | | HS Code | 29239000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2 |
| | Tetramethylammonium acetate Usage And Synthesis |
| Chemical Properties | clear colorless to pale yellow solution | | Uses | Tetramethylammonium acetate is used as an intermediate in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. Further, it is used to prepare (1R,4S)-4-hydroxycyclopent-2-en-1-essigsaeure-methylester by reacting with 1,3-dimethyl-imidazolidin-2-one. In addition to this, it serves as an emulsifier, catalyst, sterilizer, antistatic and antiseptic agent. | | Synthesis | General procedure for the synthesis of tetramethylammonium acetate from tetramethylammonium hydroxide and glacial acetic acid: 247 mg (4.11 mmol) of glacial acetic acid and 1.50 g (4.11 mmol) of tetramethylammonium hydroxide (25% wt. of methanol solution) were dissolved in 10 mL of methanol. The reaction mixture was stirred at 40°C for 4 hours. Upon completion of the reaction, the reaction solution was filtered and the solvent was subsequently removed using a rotary evaporator to give a viscous oil which gradually solidified. The residual trace solvent was removed under high vacuum to give a white solid product. The white solid was washed with ether and subsequently dried under vacuum to give 480 mg of white solid tetramethylammonium acetate in 87.6% yield. | | References | [1] Patent: US2010/105770, 2010, A1. Location in patent: Page/Page column 12 |
| | Tetramethylammonium acetate Preparation Products And Raw materials |
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