异丙烟肼
| 中文名称 | 异丙烟肼 |
|---|---|
| 中文同义词 | 异丙烟肼;N'-异丙基异烟肼;异烟酰异丙肼;化合物 T20085;N'-异丙基吡啶-4-酰肼;异烟酸2-异丙基酰肼;N'-异丙基吡啶-4-酰肼 |
| 英文名称 | iproniazid |
| 英文同义词 | iproniazid;IPRAZID;N'-propan-2-ylpyridine-4-carbohydrazide;N'-Isopropylpyridine-4-Carbohydrazide;1-Isonicotinoyl-2-isopropylhydrazine;Isonicotinic Acid 2-Isopropylhydrazide;Iproniazid>Marsilid |
| CAS号 | 54-92-2 |
| 分子式 | C9H13N3O |
| 分子量 | 179.22 |
| EINECS号 | 200-218-8 |
| 相关类别 | 药物成分 (研究实验用);Aromatics;Heterocycles;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals |
| Mol文件 | 54-92-2.mol |
| 结构式 |  |
异丙烟肼 性质
| 熔点 | 112.5-113.5° |
|---|---|
| 沸点 | 311.75°C (rough estimate) |
| 密度 | 1.1305 (rough estimate) |
| 折射率 | 1.5100 (estimate) |
| 储存条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 溶解度 | 可溶于DMSO（少许）、甲醇（少许） |
| 酸度系数(pKa) | 11.28±0.23(Predicted) |
| 形态 | 固体 |
| 颜色 | 浅米色 |
| CAS 数据库 | 54-92-2 |
安全信息
| 海关编码 | 2933399990 |
|---|---|
| 毒性 | An isopropyl derivative of isoniazid that was found to have mood-elevating effects in tuberculosis patients. It was later found to be a monoamine oxidase (MAO) inhibitor and, although not currently approved for clinical use as an antidepressant due to its propensity to cause liver damage it led to the development of other MAO inhibitors currently in use. In addition to hepatotoxic effects, iproniazid is a hypotensive agent and can cause potentially hazardous reactions with other drugs and amine-rich foods. |