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D(+)-Tryptophan

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Company Name: Taizhou Tianhong Biochemistry Technology Co., Ltd.
Tel: 0523-86132544
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Products Intro: Product Name:D-(+)-Tryptophan
CAS:153-94-6
Purity:99% Package:10g;100g;1Kg;25kg
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:D(+)-Tryptophan
CAS:153-94-6
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
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Products Intro: Product Name:D(+)-Tryptophan
CAS:153-94-6
Purity:99% Package:100g,500g,1kg,5kg,10kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
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Products Intro: CAS:153-94-6
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Mainchem Co., Ltd.
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Email: sales@mainchem.com
Products Intro: Product Name:D(+)-Tryptophan
CAS:153-94-6

Lastest Price from D(+)-Tryptophan manufacturers

  • D(+)-Tryptophan
  • US $100.00 / KG
  • 2019-07-06
  • CAS:153-94-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: Customized
D(+)-Tryptophan Basic information
Description Description Characteristics and Functions Project Standards Application References References
Product Name:D(+)-Tryptophan
Synonyms:D-TRP;D(+)-TRYPTOPHAN;D-TRYPTOPHAN;D-TRYPTOPHANE;D-2-AMINO-3-(3-INDOLYL)PROPIONIC ACID;D-2-AMINO-3-INDOLEPROPIONIC ACID;D-2-AMINO-3-INDOLYLPROPANOIC ACID;D-ALPHA-AMINO-3-INDOLEPROPIONIC ACID
CAS:153-94-6
MF:C11H12N2O2
MW:204.23
EINECS:205-819-9
Product Categories:-;Amino Acids Derivatives;Amino Acid Derivatives;Tryptophan [Trp, W];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;Indoles;Tryptophans;Chiral Compound;Amino Acids;Thiophenes;Amino Acids & Derivatives;Aromatics;Heterocycles;Indole Derivatives;Isotope Labelled Compounds;Intermediate of Tadalafil;tadalafil intermediate
Mol File:153-94-6.mol
D(+)-Tryptophan Structure
D(+)-Tryptophan Chemical Properties
Melting point 282-285 °C (dec.)(lit.)
alpha 31.5 º (c=1, H2O 24 ºC)
Boiling point 342.72°C (rough estimate)
density 1.1754 (rough estimate)
refractive index 31 ° (C=1, H2O)
storage temp. Store at RT.
form Powder
color White to slightly yellow
Water Solubility 11 g/L (20 ºC)
BRN 86198
Stability:Stable. Incompatible with oxidizing agents.
InChIKeyQIVBCDIJIAJPQS-SECBINFHSA-N
CAS DataBase Reference153-94-6(CAS DataBase Reference)
EPA Substance Registry SystemD-Tryptophan(153-94-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-41-37/38-22
Safety Statements 24/25-36/37/39-36-26
WGK Germany 3
RTECS YN6129000
8
TSCA Yes
HazardClass IRRITANT
HS Code 29339990
MSDS Information
ProviderLanguage
(R)-2-Amino-3-(3-indolyl)propionic acid English
ACROS English
SigmaAldrich English
ALFA English
D(+)-Tryptophan Usage And Synthesis
DescriptionD(+)-tryptophan is the D-form (non-proteinogenic form) of the amino acid tryptophan. It can be used for Human embryonic kidney cell (HEK-293, ATCC: CRL-1573) culture. It is also a sweetener used to study the release of incretins from enteroendocrine cells triggered by sugar but not by sweeteners.
DescriptionD-tryptophan (Full name D (+)-Tryptophan) is a white to pale yellow or white crystalline powder at room temperature, odorless or slight odor, slightly sweet taste. Solubility in water is 1.14 g (25 ℃), soluble in dilute acid and alkali, stable in alkali, decomposed in strong acid, slightly soluble in ethanol, not soluble in chloroform, ethyl ether. It plays an important role for human and animal growth and development, metabolism, known as the second essential amino acids. They are almost identical with L-type and physical and chemical properties, and only the optical activity is opposite. But their distribution, function and coenzyme have diversity. Its melting point is very high, generally above 200 degrees. It can dissolve in water, and in the near UV region it has the ability to absorb light.
Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG. the D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). The distinguishing structural characteristic of tryptophan is that it contains an indole functional group. It is an essential amino acid as defined by its growth effects on rats.
Characteristics and FunctionsD-tryptophan amino acid, as a non-reactive protein, has special physiological properties. It can be used as a non-nutritive sweeteners, feed additive, plant growth agents in food feed industry and agriculture. In the pharmaceutical industry, it mainly used for the synthesis of various polypeptides, instead of L-tryptophan peptide drug for half-life extending and reduce the side effects, but it will not resistant to the front body, and it will become important enzyme inhibitor. It can also improve the body's immunity, delayed allergic reactions. Most peptide antibiotic can resistant gram-positive bacteria, Gram-negative bacteria and some, such as Pseudomonas aeruginosa, mycobacteria, fungi, bacteria, pathogens and tumor cells, which have better inhibit and kill ability.
D-tryptophan can be used for the synthetic of semi-synthetic antibiotics, for which pharmacological plays an important role for the side chain. The peptide bond is difficult to be β-lactam enzyme action, thus high stability, and has broad antibacterial spectrum, toxicity, hypoallergenic, rapid absorption, high blood concentrations of the drug long duration.
Project StandardsAppearance  white or slightly yellow crystalline powder
Content 99.0%~101.0%
Specific rotation [α] D20 + 30.5 °~+ 32.5 °
Transmittance ≥95.0%
Acidity PH 5.5~6.4
Loss on drying ≤0.2%
Residue on ignition ≤0.1%
Chloride [Cl-] ≤0.02%
Sulphate [SO42-] ≤0.02%
Ammonium [NH4 +] ≤0.02%
Heavy metals [Pb] ≤10ppm
Ferric [Fe] ≤10ppm
Arsenic salt [As2O3] ≤1ppm
Other amino acids compliance
ApplicationAn important nutrient, niacin is used as the control agent Medicine
Production method: D-tryptophan as raw material, chloroacetic anhydride was added under cooling state after polishing sulfuric acid in ice water, filtered and recrystallized from water, and finally treatment with carboxypeptidase trypsin to remove L-type, acidified with acetic acid, ethanol recrystallization refining.
Referenceshttps://pubchem.ncbi.nlm.nih.gov/compound/D-Tryptophan#section=Top
ReferencesFujita, Yukihiro, et al. "Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo." American Journal of Physiology Endocrinology & Metabolism 296.3(2009):E473.
Bacchus, W, W. Weber, and M. Fussenegger. "Increasing the dynamic control space of mammalian transcription devices by combinatorial assembly of homologous regulatory elements from different bacterial species." Metabolic Engineering 15.1(2013):144.
Chemical Propertieswhite powder
UsesAn essential amino acid found in naturally produced pedtides. Unlike its stereoisomer, L-tryptophan, it is not used in structural or enzyme proteins.
UsesAn essential amino acid found in naturally produced peptides. Unlike its stereoisomer, L-tryptophan, it is not used in structural or enzyme proteins.
DefinitionChEBI: The D-enantiomer of tryptophan.
General DescriptionWhite solid.
Air & Water ReactionsSlightly soluble in water.
Reactivity ProfileAmines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Fire HazardFlash point data are not available for D(+)-Tryptophan, but D(+)-Tryptophan is probably combustible.
D(+)-Tryptophan Preparation Products And Raw materials
Raw materialsDL-Tryptophan-->Chloroacetic anhydride
Tag:D(+)-Tryptophan(153-94-6) Related Product Information
D(-)-Glutamic acid D-Valine D-Alanine FMOC-D-TRP(BOC)-OPFP H-D-TRP(BOC)-OH 4-CHLOROBENZOYL-L-TRYPTOPHAN CALCIUM SALT H-D-TRP-OBZL HCL BQ-610 BOC-NIN-FORMYL-D-TRYPTOPHAN Z-GLY-D-TRP-OH CBZ-D-TRYPTOPHAN N-ACETYL-D-TRYPTOPHAN Fmoc-D-Trp(Boc)-OH Fmoc-D-tryptophan H-GLY-D-TRP-OH H-D-TRP-OET HCL FMOC-D-TRP-OPFP D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID