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6-Aminocaproic acid

6-Aminocaproic acid Suppliers list
Company Name: career henan chemical co
Tel: +86-371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:6-Aminocaproic acid
CAS:60-32-2
Purity:99 Package:1KG;40USD|10KG;308USD
Company Name: Shenzhen Sendi Biotechnology Co.Ltd.
Tel: 0755-23311925 18102838259
Email: Abel@chembj.com
Products Intro: Product Name:6-Aminocaproic acid
CAS:60-32-2
Purity:99% Package:99/KG
Company Name: Mainchem Co., Ltd.
Tel: +86-0592-6210733
Email: sales@mainchem.com
Products Intro: Product Name:6-Aminocaproic acid
CAS:60-32-2
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +86 21 5161 9050/ 5187 7795
Email: ivan@atkchemical.com
Products Intro: Product Name:6-Aminocaproic acid
CAS:60-32-2
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
Company Name: Anhui Royal Chemical Co., Ltd.
Tel: +86-025-86736275
Email: dana.jiang@royal-chem.com
Products Intro: Product Name:6-Aminocaproic acid
CAS:60-32-2
Purity:99.00% Package:25kg/drum;200kg/drum

Lastest Price from 6-Aminocaproic acid manufacturers

  • 6-Aminocaproic Acid
  • US $6.55 / KG
  • 2019-10-19
  • CAS:60-32-2
  • Min. Order: 1KG
  • Purity: 99.50% in stock
  • Supply Ability: 5000.00 MT per month
6-Aminocaproic acid Basic information
Description References
Product Name:6-Aminocaproic acid
Synonyms:6-Aminohexanoic acid 60-32-2;Pyrogallol ;6-Aminocaproic acid 60-32-2 6-Aminohexanoic acid;177 J.D;177 J.D.;177j.d.;177jd;6-amino-hexanoicaci
CAS:60-32-2
MF:C6H13NO2
MW:131.17
EINECS:200-469-3
Product Categories:-;AMICAR;Pharmaceutical raw materials;Amino Acids;Organic acids;omega-Aminocarboxylic Acids;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Fibrinogen/Thrombin
Mol File:60-32-2.mol
6-Aminocaproic acid Structure
6-Aminocaproic acid Chemical Properties
Melting point 207-209 °C (dec.)(lit.)
Boiling point 242.49°C (rough estimate)
density 1.03 g/mL at 20 °C
vapor pressure <0.1 hPa (20 °C)
refractive index 1.4870 (estimate)
Fp 207-209°C
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form powder
pka4.373(at 25℃)
color white
PH7.0-7.5 (50g/l, H2O, 20℃)
Water Solubility SOLUBLE
Merck 14,432
BRN 906872
InChIKeySLXKOJJOQWFEFD-UHFFFAOYSA-N
CAS DataBase Reference60-32-2(CAS DataBase Reference)
NIST Chemistry ReferenceHexanoic acid, 6-amino-(60-32-2)
EPA Substance Registry SystemHexanoic acid, 6-amino-(60-32-2)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 2
RTECS MO6300000
TSCA Yes
HS Code 29224995
Hazardous Substances Data60-32-2(Hazardous Substances Data)
ToxicityLD50 in rats (g/kg): 7.0 i.p.; ~3.3 i.v. (Hallesy)
MSDS Information
ProviderLanguage
6-Aminohexanoic acid English
SigmaAldrich English
ACROS English
ALFA English
6-Aminocaproic acid Usage And Synthesis
Description6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.
Referenceshttps://pubchem.ncbi.nlm.nih.gov/compound/6-aminohexanoic_acid#section=Pharmacology-and-Biochemistry
https://en.wikipedia.org/wiki/Aminocaproic_acid
Chemical Propertieswhite crystalline powder
Useshemostatic
Uses6-Aminohexanoic Acid is a reagent commonly used for the extraction of aldehydes from reaction mixtures. 6-Aminohexanoic Acid has also been shown to improve solubilization of membrane proteins in elect rophoresis. Studies suggest that 6-Aminohexanoic Acid inhibits the activation of the first component of the complement system.
UsesPropylparaben Food preservative
UsesEACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.
DefinitionChEBI: An amino-acid anion that is the conjugate base of 6-aminohexanoic acid.
Brand nameAmicar (Xanodyne).
Safety ProfileModerately toxic by intravenous route. Human systemic effects by ingestion: changes in tubules (includmg acute renal failure, acute tubular necrosis), hematuria, and increased body temperature. Experimental reproductive effects. An eye irritant. When heated to decomposition it emits toxic fumes such as NOx,.
Veterinary Drugs and TreatmentsAminocaproic acid has been used as a treatment to degenerative myelopathy (seen primarily in German shepherds), but no controlled studies documenting its efficacy were located. There is interest in evaluating aminocaproic acid for adjunctive treatment of thrombocytopenia in dogs, but efficacy and safety for this purpose remains to be investigated. In humans, it is primarily used for treating hyperfibrinolysis-induced hemorrhage.
6-Aminocaproic acid Preparation Products And Raw materials
Preparation ProductsGabexate mesylate-->Capobenic acid
Raw materialsAmmonium hydroxide-->2-Oxohexamethylenimine-->AMBERLITE IR-120
Tag:6-Aminocaproic acid(60-32-2) Related Product Information
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