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| | 4-Bromo-1-naphthylamine Basic information |
| | 4-Bromo-1-naphthylamine Chemical Properties |
| Melting point | 102-103 °C(lit.) | | Boiling point | 338.4±17.0 °C(Predicted) | | density | 1.563±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 2.93±0.10(Predicted) | | color | White to Amber to Dark purple | | InChI | InChI=1S/C10H8BrN/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H,12H2 | | InChIKey | LIUKLAQDPKYBCP-UHFFFAOYSA-N | | SMILES | C1(N)=C2C(C=CC=C2)=C(Br)C=C1 | | CAS DataBase Reference | 2298-07-9(CAS DataBase Reference) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-20/21/22 | | Safety Statements | 26-37/39-36 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29214500 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 4-Bromo-1-naphthylamine Usage And Synthesis |
| Chemical Properties | pale purple fibrous powder | | Uses | 1-Amino-4-bromonaphthalene is a reagent used in catalytic asymmetric ring opening of meso-epoxides with aromatic amines in water. It can also be used to synthesize of 4-quinolones and quinolone heterocycles. | | Synthesis | 4-Bromo-1-naphthylamine is synthesised using 1-(acetylamino)-4-bromonaphthalene as a raw material by chemical reaction. The specific synthesis steps are as follows:
The 4-bromo-1-acetamido naphthalene obtained in the first step is dissolved in 100 mL of 95% ethanol, and the mass concentration of 4-bromo-1-acetylaminonaphthalene in the mixed solution is 30%, and the mass concentration is 37% added to the mixed solution. 50mL of concentrated hydrochloric acid, reacted at 80 ° C for 6h, filtered and dried to give 4-bromo-1-naphthylamine.
 | | References | [1] Synthesis, 2004, # 17, p. 2809 - 2812
[2] Journal of the Brazilian Chemical Society, 2010, vol. 21, # 3, p. 496 - 501
[3] Journal of the Chinese Chemical Society, 2005, vol. 52, # 3, p. 559 - 562
[4] Synthetic Communications, 2005, vol. 35, # 14, p. 1947 - 1952
[5] Russian Journal of Organic Chemistry, 2007, vol. 43, # 9, p. 1282 - 1284 |
| | 4-Bromo-1-naphthylamine Preparation Products And Raw materials |
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