4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

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4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Suppliers list
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Products Intro: Product Name:4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol
CAS:109806-71-5
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
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CAS:109806-71-5
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Products Intro: Product Name:2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethanol
CAS:109806-71-5
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Products Intro: Product Name:4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORID
CAS:109806-71-5
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Products Intro: Product Name:2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethanol
CAS:109806-71-5
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Basic information
Product Name:4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
Synonyms:2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZIN-1-YL}-ETHANOL;2-[4-{Chlorophenyl}Phenylmethyl]-1-;2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol;4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone;1-Piperazineethanol, 4-[(4- chlorophenyl)phenylMethyl]-;Levocetirizine Impurity G;(R)-2-(4-((4-chlorophenyl);Levocetirizine Impurity 6
CAS:109806-71-5
MF:C19H23ClN2O
MW:330.85
EINECS:
Product Categories:(intermediate of cetirizine dihydrochloride)
Mol File:109806-71-5.mol
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Structure
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Chemical Properties
Boiling point 205-208 °C(Press: 0.1 Torr)
density 1.191±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Ethyl Acetate (Slightly), Methanol (Slightly)
form Solid
pka14.96±0.10(Predicted)
color White to Off-White
Stability:Very Hygroscopic
InChIInChI=1S/C19H23ClN2O/c20-18-8-6-17(7-9-18)19(16-4-2-1-3-5-16)22-12-10-21(11-13-22)14-15-23/h1-9,19,23H,10-15H2
InChIKeyZJQSBXXYLQGZBR-UHFFFAOYSA-N
SMILESN1(CCO)CCN(C(C2=CC=C(Cl)C=C2)C2=CC=CC=C2)CC1
CAS DataBase Reference109806-71-5(CAS DataBase Reference)
Safety Information
MSDS Information
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Usage And Synthesis
Chemical PropertiesOff-White Solid
Uses2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethanol is an impurity of (R)-Cetirizine (C281106).
Uses4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materialsTetrahydrofuran-->Dichloromethane-->Thionyl chloride-->Toluene-->Triethylamine-->Benzene-->1,4-Dioxane-->Sodium borohydride-->Isopropyl alcohol-->Piperazine-->Calcium chloride-->2-Bromoethanol-->4-Chlorobenzophenone-->1-(4-Chlorobenzhydryl)piperazine
Preparation Products1-Piperazineacetaldehyde-->Cetirizine
Tag:4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE(109806-71-5) Related Product Information
Ethanol Levocetirizine Hydrochloride Impurity F Acetic acid, 2-[2-[2-[4-[(4- chlorophenyl)phenylMethyl]-1-piperazinyl]ethoxy]ethoxy]- 4-[(4-chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride (intermediate of cetirizine dihydrochloride) Hydroxyzine-D8 Dihydrochloride Cetirizine (S)-Cetirizine Acetamide, 2-(2-(4-((2-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy )-, dihydrochloride Hydroxyzine dihydrochloride Levocetirizine 4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE