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DOXEPIN

DOXEPIN Suppliers list
Company Name: BOC Sciences
Tel: 1-631-619-7922
Email: inquiry@bocsci.com
Products Intro: Product Name:Doxepin
CAS:1668-19-5
Purity:>95%
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Email: sales@alchempharmtech.com
Products Intro: Product Name:3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine
CAS:1668-19-5
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-46179
Company Name: career henan chemical co
Tel: 0086-371-86658258
Email: factory@coreychem.com
Products Intro: Product Name:DOXEPIN
CAS:1668-19-5
Purity:99% Package:1KG;7USD
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801
Email: 3bsc@sina.com
Products Intro: Product Name:Doxepin hydrochloride;11-(3-diMethylaMinopropylidene)-6,11-dihydrodibenz[b,e]oxepinhydrochloride
CAS:1668-19-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: LGM Pharma  
Tel: 1-(800)-881-8210
Email: inquiries@lgmpharma.com
Products Intro: Product Name:Doxepin
CAS:1668-19-5
Purity:Typically NLT 98%

Lastest Price from DOXEPIN manufacturers

  • DOXEPIN
  • US $7.00 / KG
  • 2020-01-10
  • CAS:1668-19-5
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
DOXEPIN Basic information
Product Name:DOXEPIN
Synonyms:3-Dibenz[b,e]oxepin-(6H)-ylidene-N,N-dimethyl-1-propanamine;3-Dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-1-propanamine;Aponal;Curatin;Dibenz(b,e)oxepin-delta11(6H),gamma-propylamine, N,N-dimethyl-;Docepin;Doxepine;e)oxepin-delta(11(6h),gamma)-propylamine,n,n-dimethyl-dibenz(
CAS:1668-19-5
MF:C19H21NO
MW:279.38
EINECS:214-966-8
Product Categories:Heterocyclic Compounds;Neurochemicals
Mol File:1668-19-5.mol
DOXEPIN Structure
DOXEPIN Chemical Properties
Melting point 187-189°C
Boiling point bp0.03 154-157°; bp0.2 260-270°
density 1.0594 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. Store at RT
pka9.40±0.28(Predicted)
Water Solubility 31.57mg/L(25 ºC)
EPA Substance Registry SystemDoxepin (1668-19-5)
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 36/37/39-45
ToxicityLD50 in mice, rats (mg/kg): 26, 16 i.v.; 79, 182 i.p.; 135, 147 orally (Ribbentrop, Schaumann)
MSDS Information
DOXEPIN Usage And Synthesis
UsesUsed clinically to treat anxiety and depression. Antidepressant
DefinitionChEBI: A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Brand nameApo-doxepin;Co dox;Deptran;Doksapan;Dolat;Doxal;Doxedyn;Doxepin hcl;Gilex;Novo-doxepin;Novoxapin;Sinequan;Sinquan concentrate;Sinquane;Tolllluan;Triadapin;Zonalon.
World Health Organization (WHO)Doxepin, a tricyclic antidepressant was introduced in 1964 for the management of endogenous depression. Much of the adverse effects are caused by its antimuscarinic actions. These include dry mouth, cardiac arrhythmias, central nervous system disturbances, blood disorders and risk of suicide. The risk of suicide and dangers related to overdosage led the Norwegian Medicines Control Authority to put the higher strength formulation under prescribing restriction in 1992. The risk of death following overdosage is apparently higher for products containing tricyclic compounds as compared with nontricyclic products.
Biological ActivityHighly potent H 1 histamine receptor antagonist (K d = 310 pM) and tricyclic antidepressant. Also binds to the H 4 histamine receptor (pK i = 6.79).
Contact allergensThis benzoxepin tricylcic drug has antidepressant, anticholinergic, antiitching, and antihistamine properties. After oral use, it has been developed as a topical antiitching agent. Allergic contact dermatitis is not infrequent.
DOXEPIN Preparation Products And Raw materials
Raw materialsTriphenylphosphine-->Dimethylamine-->Bromobenzene-->1-Bromopropane-->1,3-Dibromopropane-->hydracide
Tag:DOXEPIN(1668-19-5) Related Product Information
5-Hydroxytryptophan Penfluridol Doxepin hydrochloride DOXEPIN INTERMEDIATES Pinoxepin Olopatadine DOXEPIN-D3 HCL (N-METHYL-D3) DOXEPIN HYDROCHLORIDE [N-METHYL-3H] DOXEPIN