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| | 3-Fluoro-4-hydroxybenzoic acid Basic information |
| | 3-Fluoro-4-hydroxybenzoic acid Chemical Properties |
| Melting point | 154-158 °C (lit.) | | Boiling point | 311.9±27.0 °C(Predicted) | | density | 1.492±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | pka | 4.23±0.10(Predicted) | | form | Powder or Crystalline Powder | | color | Off-white to brown | | Water Solubility | Slightly soluble in water. | | BRN | 2829823 | | InChI | 1S/C7H5FO3/c8-5-3-4(7(10)11)1-2-6(5)9/h1-3,9H,(H,10,11) | | InChIKey | IUSDEKNMCOUBEE-UHFFFAOYSA-N | | SMILES | OC(=O)c1ccc(O)c(F)c1 | | CAS DataBase Reference | 350-29-8(CAS DataBase Reference) |
| Hazard Codes | Xi,C | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | Hazard Note | Corrosive | | TSCA | N | | HazardClass | IRRITANT | | HS Code | 29163990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
| | 3-Fluoro-4-hydroxybenzoic acid Usage And Synthesis |
| Chemical Properties | Yellow solid | | Uses | 3-Fluoro-4-hydroxybenzoic acid may be used in the preparation of (S)-2-methylbutyl-3-fluoro-4-hydroxy benzoate and 4-n-alkoxy-3-fluorobenzoic acids. It may also be used in the synthesis of bis 3-fluoro-4-hydroxybenzoates, which are potent KCa2/3 pan-inhibitors. | | General Description | 3-Fluoro-4-hydroxybenzoic acid is a halo-substituted 4-hydroxybenzoic acid that can be prepared from 3-fluoro-4-methoxybenzoic acid via demethylation. |
| | 3-Fluoro-4-hydroxybenzoic acid Preparation Products And Raw materials |
| Raw materials | 1,3-Benzodioxole-5-carboxylic acid, hexahydro-5,7-dihydroxy-2,2-dimethyl-, (3aR,5R,7R,7aS)--->1,3-Benzodioxole-5-carboxylic acid, hexahydro-5,7-dihydroxy-2,2-dimethyl-, methyl ester, (3aR,5R,7R,7aS)--->3-Fluoro-4-hydroxybenzonitrile-->3-Fluoro-4-methoxybenzoic acid-->4-Bromo-2-fluoroanisole-->4-Bromo-2-fluorophenol-->3,5-Difluoro-4-hydroxybenzoic acid-->3-Fluoro-2-hydroxybenzoic acid-->Quinic acid-->4-Hydroxybenzoic acid-->2-Fluoroanisole | | Preparation Products | 3-Fluoro-4-hydroxybenzamide |
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