|
|
| | Thiazole-5-carboxaldehyde Basic information |
| | Thiazole-5-carboxaldehyde Chemical Properties |
| Melting point | 229 °C (decomp) | | Boiling point | 92-94 °C/16 mmHg | | density | 1.304 g/mL at 25 °C | | refractive index | 1.5874 | | Fp | 98 °C | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to lump to clear liquid | | pka | 0.94±0.10(Predicted) | | color | White or Colorless to Yellow | | InChIKey | ZXRLWHGLEJGMNO-UHFFFAOYSA-N | | CAS DataBase Reference | 1003-32-3(CAS DataBase Reference) |
| | Thiazole-5-carboxaldehyde Usage And Synthesis |
| Chemical Properties | White to brown liquid or solid | | Uses | Thiazole-5-carboxaldehyde is used in the synthesis of imidazoles with cardiomyocyte proliferation activity for heart disease treatments. | | Synthesis Reference(s) | Synthetic Communications, 25, p. 4081, 1995 DOI: 10.1080/00397919508011485
Synthesis, p. 998, 1987 DOI: 10.1055/s-1987-28146 | | Purification Methods | Dry the aldehyde over Na2SO4 and fractionate it in a vacuum. The 2,4-dinitrophenylhydrazone forms red crystals from MeOH with m 238-240o, and the semicarbazone has m 210-212o (from MeOH). [Erne et al. Helv Chim Acta 34 148 1951, Beilstein 27 III/IV 2615.] |
| | Thiazole-5-carboxaldehyde Preparation Products And Raw materials |
|