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| | Pyridazine Chemical Properties |
| Melting point | −8 °C(lit.)
| | Boiling point | 208 °C(lit.)
| | density | 1.103 g/mL at 25 °C(lit.)
| | refractive index | n20/D 1.524(lit.)
| | Fp | 185 °F
| | storage temp. | Refrigerator | | pka | 2.24(at 20℃) | | form | Liquid | | color | Clear yellow-brown | | Water Solubility | MISCIBLE | | Merck | 14,7969 | | BRN | 103906 | | CAS DataBase Reference | 289-80-5(CAS DataBase Reference) | | NIST Chemistry Reference | Pyridazine(289-80-5) |
| Hazard Codes | Xn | | Risk Statements | 36/37/38-22 | | Safety Statements | 23-24/25 | | RIDADR | NA 1993 / PGIII | | WGK Germany | 3
| | RTECS | UR5267000
| | F | 8-10 | | TSCA | Yes |
| | Pyridazine Usage And Synthesis |
| Heterocyclic compound | Pyridazine refers to a heterocyclic azine compound containing a nitrogen hexaheterocyclic , it and pyrimidine, pyrazine are isomers of each other , it is insoluble in petroleum ether, soluble in methanol, ethanol and ether, and it can be miscible with water, benzene and dimethyl formamide immiscibility. Pyridazine is a weak base, which can form salts with picric acid, and hydrochloric acid; pyridazine is not prone to nucleophilic and electrophilic aromatic substitution reaction; it is stable to potassium permanganate; sodium or alcohols may be reduced open-chain , and converted to 1,4-diaminobutane.
Pyridazine is widely used as pharmaceutical raw materials, such as long-term sulfa SMP which is pyridazine derivative, 4-amino-cinnoline which belongs to antimalarials, blood pressure drug hydralazine, etc. all use pyridazine as raw materials; it can also be used as raw material of pesticides, for the production of herbicides, "herbicide-sensitive", "Milstem", "bromine herbicide-sensitive", "Kusakira," "maleic hydrazide", "Norflurazon", "pyridate "" insecticide "," imputed phosphorus "and so on.
The above information is edited by the chemicalbook of Tian Ye.
| | Chemical Properties | Clear yellowish-brown liquid |
| | Pyridazine Preparation Products And Raw materials |
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