- Oxindole
-
- $29.00
-
2026-08-08
- CAS:59-48-3
- Purity: 99.65%
- Supply Ability: 10g
- Oxindole
-
- $29.00
-
2026-08-08
- CAS:59-48-3
- Purity: 99.65%
- Supply Ability: 10g
- Oxindole
-
- $9.00
-
2026-05-28
- CAS:59-48-3
- Min. Order: 1KG
- Purity: 99.9
- Supply Ability: 1 ton
Related articles - Synthesis of 2-Oxindole
- 2-Oxindole is a bicyclic nitrogen heterocycle with a carbonyl function at position 2 of the fused pyrrole ring, having two pos....
- Jan 24，2022
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| | Oxindole Basic information |
| | Oxindole Chemical Properties |
| Melting point | 123-128 °C(lit.) | | Boiling point | 227 °C73 mm Hg(lit.) | | density | 1.1475 (rough estimate) | | refractive index | 1.5282 (estimate) | | Fp | 194-196°C/17mm | | storage temp. | Sealed in dry,Room Temperature | | solubility | 9.1g/l | | pka | 14.77±0.20(Predicted) | | form | Solid | | color | Light Brown | | Water Solubility | insoluble | | BRN | 114692 | | InChI | 1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10) | | InChIKey | JYGFTBXVXVMTGB-UHFFFAOYSA-N | | SMILES | O=C1Cc2ccccc2N1 | | CAS DataBase Reference | 59-48-3(CAS DataBase Reference) | | NIST Chemistry Reference | 2H-Indol-2-one, 1,3-dihydro-(59-48-3) | | EPA Substance Registry System | Oxindol (59-48-3) |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 22-24/25 | | RIDADR | 2811 | | WGK Germany | 3 | | RTECS | NM2080500 | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29337900 | | Storage Class | 11 - Combustible Solids |
| | Oxindole Usage And Synthesis |
| Chemical Properties | beige to yellowish-orange or pinkish-brown powder | | Uses | Indole analogue; shows pharmacological activity | | Uses | Oxindole is considered as indole analogue, which shows pharmacological activity. | | Definition | ChEBI:
Indolin-2-one is an indolinone carrying an oxo group at position 2. It is an indolinone and a gamma-lactam. | | Hazard | Causes flaccid paralysis without anesthesia (usually neuromuscular blockage), changes in motor activity, and ataxia in oral and intraperitoneal lethal-dose studies of mice; May cause irritation; Harmful by ingestion. | | Solubility in organics | Oxindole is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide (DMF), which should be purged with an inert gas. The solubility of oxindole in ethanol and DMF is approximately 10 mg/ml and approximately 3 mg/ml in DMSO. Oxindole is sparingly soluble in aqueous buffers. |
| | Oxindole Preparation Products And Raw materials |
| Raw materials | 4-chlorobenzo[d]oxazol-2(3H)-one-->2',6'-Dichloroformanilide-->1-(2,6-Dichlorophenyl)-2-hydroindole-->Benzene, 1,3-dichloro-2-isocyano- (9CI)-->Diclofenac sodium-->2,6-Dichlorophenyl isocyanate-->9(10H)-Acridinone, 4-chloro--->2,6-Dichloronitrobenzene-->2,6-Dichlorodiphenylamine | | Preparation Products | 5-Bromo-2-oxindole-->5-Acetyloxindole-->10,15-Dihydro-5H-diindolo[3,2-a:3',2'-c]carbazole-->3-[(2,4-Dimethylpyrrol-5-yl)methylidenyl]-2-indolinon-->5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl) indolin-2-one-->1-Methyl-2-indolinone |
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